Inhibition of Growth Hormone Receptor Activation by Pegvisomant may Increase Bone Density in Acromegaly

2010 ◽  
Vol 43 (01) ◽  
pp. 55-61 ◽  
Author(s):  
C. Jimenez ◽  
M. Ayala-Ramirez ◽  
J. Liu ◽  
R. Nunez ◽  
R. F. Gagel
Keyword(s):  
Growth Hormone ◽  
Bone Density ◽  
Hormone Receptor ◽  
Growth Hormone Receptor ◽  
Receptor Activation ◽  
Inhibition Of Growth

scholarly journals Endotoxin-Induced Inhibition of Growth Hormone Receptor Signaling in Rat Liver in Vivo1

Endocrinology ◽  
1999 ◽  
Vol 140 (12) ◽  
pp. 5505-5515 ◽  
Author(s):  
Yilei Mao ◽  
Pei-Ra Ling ◽  
Timothy P. Fitzgibbons ◽  
Karen C. McCowen ◽  
G. Peter Frick ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Rat Liver ◽  
Hormone Receptor ◽  
Growth Hormone Receptor ◽  
Receptor Signaling ◽  
Inhibition Of Growth

Model for growth hormone receptor activation based on subunit rotation within a receptor dimer

2005 ◽  
Vol 12 (9) ◽  
pp. 814-821 ◽  
Author(s):  
Richard J Brown ◽  
Julian J Adams ◽  
Rebecca A Pelekanos ◽  
Yu Wan ◽  
William J McKinstry ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Hormone Receptor ◽  
Growth Hormone Receptor ◽  
Receptor Activation ◽  
Subunit Rotation ◽  
Receptor Dimer

Laron syndrome – A case Report

JMS SKIMS ◽  
2017 ◽  
Vol 20 (2) ◽  
pp. 104-106
Author(s):  
Javaid Ahmad Bhat ◽  
Moomin Hussain Bhat ◽  
Hilal Bhat ◽  
Mona Sood ◽  
Shariq Rashid Masoodi
Keyword(s):  
Growth Hormone ◽  
Case Report ◽  
Hormone Receptor ◽  
Growth Hormone Receptor ◽  
Genetic Disorder ◽  
Female Child ◽  
Receptor Signaling ◽  
Laron Syndrome ◽  
Rare Genetic Disorder ◽  
Igf I

Background : Laron & colleagues (1966) reported a rare genetic disorder in Israliei Jewish sublings which was characterized by insensitivity to growth hormone due to abnormality in growth hormone receptor or post receptor signaling pathway.Case Report: We hereby report a case of a 5 year old female child who presented to us with features similar to Laron syndrome. The diagnosis was made & confirmed by various Lab. investigations like low IGF-I levels and managed accordingly. JMS 2017; 20 (2):104-106  

Three novel Growth Hormone Receptor (GHR) splicing mutations causing a spectrum of Growth Hormone Insensitivity

2019 ◽  
Author(s):  
Emily Cottrell ◽  
Avinaash Maharaj ◽  
Tasneem Ladha ◽  
Sumana Chatterjee ◽  
Anna Grandone ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Hormone Receptor ◽  
Growth Hormone Receptor ◽  
Splicing Mutations ◽  
Growth Hormone Insensitivity

Isolation of two types of cDNA encoding growth hormone receptor-like genes in the Japanese eel, Anguilla japonica

2002 ◽  
Vol 68 (sup1) ◽  
pp. 959-960 ◽  
Author(s):  
YUICHI OZAKI ◽  
HARUHISA FUKADA ◽  
YUKINORI KAZETO ◽  
SHINJI ADACHI ◽  
AKIHIKO HARA ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Hormone Receptor ◽  
Growth Hormone Receptor ◽  
Anguilla Japonica ◽  
Japanese Eel
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