Diagnostic Accuracy of EUS-FNA for Pancreatic tumors Smaller than 20mm

Endoscopy ◽  
2011 ◽  
Vol 43 (S 03) ◽  
Author(s):  
Kaneko Maki
2016 ◽  
Vol 5 (4) ◽  
pp. 225 ◽  
Author(s):  
Atsushi Irisawa ◽  
Akane Yamabe ◽  
ManoopS Bhutani ◽  
Goro Shibukawa ◽  
Mariko Fujisawa ◽  
...  

2020 ◽  
Vol 3 (Supplement_1) ◽  
pp. 146-147
Author(s):  
A Almudaires ◽  
G Williams ◽  
S E Gruchy ◽  
A Morgenthau

Abstract Background Endoscopic ultrasound-guided fine-needle aspiration with Rapid On Site Evaluation (ROSE EUS-FNA) and endoscopic ultrasound-guided core-needle biopsy (EUS-CNB) are widely used for the diagnosis of pancreatic tumors. There is no known published randomized control trial that compares between the two modalities. Given the aggressive nature of pancreatic cancer, it is crucial to make a prompt diagnosis in order to initiate treatment in a timely fashion. Aims This study compares the diagnostic performance of ROSE EUS-FNA and EUS-CNB for diagnosis of pancreatic cancer. Methods A retrospective review was performed for patients who underwent ROSE EUS-FNA and/ or EUS-CNB for solid pancreatic lesion. Diagnostic yield (defined as percentage of diagnostic samples), diagnostic accuracy (defined as percentage of correct diagnosis), sensitivity and specificity for malignancy were compared between ROSE EUS- FNA and EUS- CNB. Baseline characteristics for both patients and lesions were also obtained. Results A total of 82 patients with solid pancreatic lesions were reviewed. 84 EUS with 61 FNA and 74 CNB were performed. The diagnostic yield was 42/61 (69%) and 59/74 (79.7%) for FNA and CNB respectively (P 0.166). The diagnostic accuracy was 33/61 (54%) and 53/74 (71%) for FNA and CNB respectively (P 0.0326). 50 patients underwent both FNA and CNB during the same EUS. The calculated diagnostic yield among this subgroup was 33/50 (66%) and 39/50 (78%) for FNA and CNB respectively (P 0.265); with diagnostic accuracy of 26/50 (52%) for FNA and 34/50 (68%) for CNB (P 0.152). The diagnostic accuracy after combining both techniques was 40/50 (80%). The incremental increase in diagnostic yield by combining both methods was 12/50 (24%) and 6/50 (12%) relative to FNA and CNB respectively. The sensitivity for the diagnosis of malignancy for FNA and CNB was 60.8% and 92.7%, respectively. The specificity was 100% for both methods. Conclusions EUS-guided CNB is a superior method of assessing solid pancreatic lesion and pancreatic malignancy with better diagnostic yield and accuracy and higher sensitivity than ROSE EUS-FNA. Funding Agencies None


2017 ◽  
Vol 49 (11) ◽  
pp. 1286-1287
Author(s):  
Andrea Lisotti ◽  
Marta Serrani ◽  
Giancarlo Caletti ◽  
Pietro Fusaroli

Pancreatology ◽  
2018 ◽  
Vol 18 (4) ◽  
pp. S93
Author(s):  
Jose Lariño-Noia ◽  
Julio Iglesias-Garcia ◽  
Ihab Abdulkader-Nallib ◽  
Daniel De la Iglesia-García ◽  
Hector Lazare ◽  
...  

Author(s):  
Ling-Yu Guo ◽  
Phyllis Schneider ◽  
William Harrison

Purpose This study provided reference data and examined psychometric properties for clausal density (CD; i.e., number of clauses per utterance) in children between ages 4 and 9 years from the database of the Edmonton Narrative Norms Instrument (ENNI). Method Participants in the ENNI database included 300 children with typical language (TL) and 77 children with language impairment (LI) between the ages of 4;0 (years;months) and 9;11. Narrative samples were collected using a story generation task, in which children were asked to tell stories based on six picture sequences. CD was computed from the narrative samples. The split-half reliability, concurrent criterion validity, and diagnostic accuracy were evaluated for CD by age. Results CD scores increased significantly between ages 4 and 9 years in children with TL and those with LI. Children with TL produced higher CD scores than those with LI at each age level. In addition, the correlation coefficients for the split-half reliability and concurrent criterion validity of CD scores were all significant at each age level, with the magnitude ranging from small to large. The diagnostic accuracy of CD scores, as revealed by sensitivity, specificity, and likelihood ratios, was poor. Conclusions The finding on diagnostic accuracy did not support the use of CD for identifying children with LI between ages 4 and 9 years. However, given the attested reliability and validity for CD, reference data of CD from the ENNI database can be used for evaluating children's difficulties with complex syntax and monitoring their change over time. Supplemental Material https://doi.org/10.23641/asha.13172129


1956 ◽  
Vol 31 (5) ◽  
pp. 551-565 ◽  
Author(s):  
Frank B. McGlone ◽  
Donald S. Robertson ◽  
John M. Grogan
Keyword(s):  

2007 ◽  
Vol 177 (4S) ◽  
pp. 649-649
Author(s):  
Ponnambalam Chandrasekar ◽  
Jeremy Raynard ◽  
Abdul Sayed ◽  
Faiyaz Kapasi ◽  
Jaspal S. Virdi ◽  
...  

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