Recent Advances in Cobalt-Catalyzed Csp2 and Csp3 Cross-Couplings

Synthesis ◽  
2017 ◽  
Vol 49 (17) ◽  
pp. 3887-3894 ◽  
Author(s):  
Jeffrey Hammann ◽  
Maximilian Hofmayer ◽  
Ferdinand Lutter ◽  
Lucie Thomas ◽  
Paul Knochel
Keyword(s):  
Transition Metal ◽  
Recent Progress ◽  
Cross Coupling ◽  
Short Review ◽  
Review Article ◽  
Transition Metal Catalysis ◽  
Coupling Reactions ◽  
Metal Catalysis ◽  
Cross Coupling Reactions ◽  
Recent Advances

The present short review article highlights recent progress in the field of transition-metal catalysis. An overview on recent work involving cobalt-catalyzed cross-coupling reactions and some recent advances from our laboratories are given.1 Introduction2 Csp2–Csp2 Cobalt-Catalyzed Cross-Couplings3 Csp2–Csp3 Cobalt-Catalyzed Cross-Couplings4 Conclusion

Recent Advances in Metal-Catalyzed, Electrochemical Coupling Reactions of sp2 Halides/Boronic Acids and sp3 Centers

Synthesis ◽  
2020 ◽  
Author(s):  
Zachary J. Gale-Day
Keyword(s):  
Cross Coupling ◽  
Short Review ◽  
Boronic Acids ◽  
Coupling Reactions ◽  
Cross Coupling Reactions ◽  
Organic Electrochemistry ◽  
Recent Advances ◽  
Electrochemical Coupling ◽  
Metal Catalyzed

AbstractTraditionally, metal-catalyzed cross-coupling reactions rely on stable but expensive metals, such as palladium. However, the recent development of synthetic organic electrochemistry allows for in situ redox manipulations, expanding the use of cheaper, abundant and sustainable metals, such as nickel and copper as efficient cross-coupling catalysts. This short review covers the recent advances in metal-catalyzed electrochemical coupling reactions, with a focus on reactions of sp2 electrophiles and nucleophiles with sp3 coupling partners to form both C–C and C–heteroatom bonds.1 Introduction2 Nickel-Catalyzed C–C sp2–sp3 Coupling Reactions3 Coupling of Aryl Groups with Heteroatomic Nuclei4 Conclusion

Recent Advances in Csp3−Csp3 Cross-Coupling via Metallaphotoredox Strategy

Synthesis ◽  
2020 ◽  
Author(s):  
Weiming Yuan ◽  
Songlin Zheng ◽  
Yuanyuan Hu
Keyword(s):  
Organic Molecules ◽  
Cross Coupling ◽  
Short Review ◽  
Coupling Reactions ◽  
Organometallic Reagents ◽  
Cross Coupling Reactions ◽  
Recent Advances ◽  
Indispensable Tool ◽  
Metal Catalyzed ◽  
Important Progress

Transition metal-catalyzed carbon-carbon cross-coupling reactions have emerged the tremendous achievements in modern synthetic chemistry and to date explored as an indispensable tool for organic molecules construction. Despite important progress in this area, the theme of joining two C(sp3)-hybridized alkyl fragments remains yet elusive. So far, the existing methods have largely relied on using organometallic reagents as the nucleophilic coupling partners, thereby inevitably limiting functional groups compatibility. Although cross-electrophile coupling may alleviate the pain somewhat, it is necessary to add stoichiometric amounts of reductant to complete the catalytic cycle. Recently, the emergence of photoredox mediated single-electron transmetallation strategy evoked an ideal paradigm for selectively manipulating C(sp3)‒C(sp3) cross-coupling with unprecedented applying native C(sp3)-functionalities instead of organometallic reagents, thus opens a new window for C(sp3)‒C(sp3) bond creation. This short review will highlight the recent advances of the exciting subfield.

Recent Advances in Decarboxylative Conversions of Cyclic Carbonates and Beyond

Synthesis ◽  
2021 ◽  
Author(s):  
Biwei Yan ◽  
Wusheng Guo
Keyword(s):  
Transition Metal ◽  
Catalytic System ◽  
Research Work ◽  
Building Blocks ◽  
Short Review ◽  
Transition Metal Catalysis ◽  
Cyclic Carbonates ◽  
Metal Catalysis ◽  
Recent Advances ◽  
Metal Catalyzed

Functionalized cyclic organic carbonates have emerged as valuable building blocks for the construction of interesting and useful molecules upon decarboxylation under transition metal catalysis in recent years. With suitable catalytic system, the development of chemo-, regio-, stereo- and enantioselective methods for the synthesis of useful and interesting compounds has advanced greatly. On the basis of previous research work on this topic, this short review will highlight the synthetic potential of cyclic carbonates under transition metal catalysis in last two years. 1 Introduction 2 Transition metal catalyzed decarboxylation of vinyl cyclic carbonates 3 Zwitterionic enolate chemistry based on transition metal catalysis 4 Decarboxylation of alkynyl cyclic carbonates and dioxazolones 5 Conclusions and perspectives

Homogeneous Gold-Catalyzed Aryl–Aryl Coupling Reactions

Synthesis ◽  
2020 ◽  
Vol 52 (14) ◽  
pp. 2017-2030 ◽  
Author(s):  
Søren Kramer
Keyword(s):  
Natural Products ◽  
Transition Metal ◽  
Palladium Catalysis ◽  
Cross Coupling ◽  
Functional Materials ◽  
Research Field ◽  
Transition Metal Catalysis ◽  
Coupling Reactions ◽  
Metal Catalysis

Synthesis of biaryl motifs are crucial for the development and synthesis of pharmaceuticals, natural products, and functional materials. During the last decade, gold-catalyzed aryl–aryl coupling reactions have evolved from a curiosity to a well-established research field. This review summarizes the field from early examples up to the latest developments. Facile C–H functionalization and orthogonal reactivity compared to many other types of transition metal catalysis, for example, palladium catalysis, makes gold-catalyzed aryl–aryl coupling reactions highly appealing and valuable.1 Introduction2 Early Examples3 Cross-Coupling with External Oxidants4 Cross-Coupling without External Oxidants5 Conclusions

Sign in / Sign up

Export Citation Format

Share Document