Myocardial perfusion SPECT with dipyridamole stress test in cardiac syndrome X

2006 ◽  
Vol 45 (03) ◽  
pp. 111-114 ◽  
Author(s):  
I. Smolarek ◽  
D. Rogacka ◽  
M. Kazmiercźak ◽  
H. Wysocki ◽  
J. Sowiński ◽  
...  
Keyword(s):  
Myocardial Perfusion ◽  
Stress Test ◽  
Myocardial Perfusion Spect ◽  
Syndrome X ◽  
Cardiac Syndrome X ◽  
Cardiac Syndrome ◽  
Significant Difference ◽  
Perfusion Spect ◽  
99Mtc Mibi ◽  
Dipyridamole Stress

SummaryCardiac syndrome X defines patients with typical anginal chest pain, a positive exercise ECG stress test and angiographically normal coronary arteries. Aim of this study was to evaluate the role of myocardial perfusion SPECT with dipyridamole stress in the diagnosis of cardiac syndrome X. Patients, methods: 68 patients with syndrome X aged 32 to 60 years were subjected to myocardial imaging using 99mTc-MIBI according to the two-days protocol: at rest and after dipyridamole infusion. Semiquantitative evaluation of the images was based on the assessment of 99mTc-MIBI uptake in 17 myocardial segments using a 5-points scale (0 point – normal uptake, 4 points – no uptake). Scores obtained in each segment were summed up, constituting the summed rest score (SRS) and summed stress score (SSS). Results: Mean SRS was 7.9 ± 4.8 and mean SSS was 7.2 ± 4.4 (non-significant difference). Individual comparison of SRS and SSS values revealed three patterns of scintigraphic images: 1) in 25 patients (36.8%), a paradoxical improvement of perfusion at stress images was found, 2) in 23 patients (33.8%), the myocardial perfusion deteriorated after dipyridamole, 3) in 20 patients (29.4%), no significant change of the myocardial perfusion between rest and stress images occurred. Conclusions: In cardiac syndrome X, myocardial SPECT with dipyridamole stress shows different patterns of myocardial perfusion that reflects heterogeneity of this pathology.

scholarly journals Frequency and severity of myocardial perfusion abnormalities using Tc-99m MIBI SPECT in cardiac syndrome X

2006 ◽  
Vol 6 (1) ◽  
Author(s):  
Mohsen Saghari ◽  
Majid Assadi ◽  
Mohammad Eftekhari ◽  
Mohammad Yaghoubi ◽  
Armaghan Fard-Esfahani ◽  
...  
Keyword(s):  
Myocardial Perfusion ◽  
Syndrome X ◽  
Cardiac Syndrome X ◽  
Cardiac Syndrome ◽  
Mibi Spect

scholarly journals Magnetic Resonance Imaging in Cardiac Syndrome X

JMS SKIMS ◽  
2011 ◽  
Vol 14 (2) ◽  
pp. 46-51
Author(s):  
Syed Maqbool Ahmad ◽  
Hilal Rather ◽  
Khurshid Iqbal ◽  
Nisar A Tramboo ◽  
Vicar Jan ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Chest Pain ◽  
Magnetic Resonance ◽  
Myocardial Perfusion ◽  
Perfusion Index ◽  
Syndrome X ◽  
Resonance Imaging ◽  
Cardiac Syndrome X ◽  
Subendocardial Ischemia ◽  
Cardiac Syndrome

BACKGROUND: Cardiac syndrome X is a subject with yet unsettled etiology and management. Conventional investigations have not been able to establish that chest pain is due to myocardial ischemia. Magnetic resonance imaging has higher resolution and is more accurate for detecting ischemia. AIMS AND OBJECTIVES: To establish subendocardial ischemia as the cause of chest pain in cardiac syndrome X by virtue of stress perfusion cardiac MRI. METHODS: Contrast enhanced cardiac MRI was performed in 15 cases and 7 matched controls both at rest and during a six minute infusion of adenosine. Both visual and quantitive analysis were performed. In quantitative analysis both myocardial perfusion index and myocardial perfusion reserve index was measured. RESULTS: There was a significant increase in myocardial perfusion in both subendocardium as well as in subepicardium in both cases as well as in controls upon stress with adenosine. In controls the subendocardial perfusion index rose from 0.13 0.3 to 0.18 .03 and in the subepicardium from 0.12 .02 to 0.18 .03. In patients with cardiac syndrome X subendocardial perfusion index rose from 0.14 .03 to 0.19 .03 and subepicardial perfusion index rose from 0.13+.03 to 0.19 .03. Visual analysis showed short lasting subendocardial dark rim artificats in both cases and controls which lasted for only 3 to 5 beats. CONCLUSION: Our cardiovascular MR study of patients with cardiac syndrome X demonstrated significant and almost similar magnitude adenosine induced increase in both subendocardial and subepicardial myocardial perfusion indices in both study as well as control group. We found no evidence of subendocardial ischemia in patients with cardiac syndrome X. JMS 2011;14(2):46-51

Myocardial Perfusion SPECT 2018 in Germany: Results of the 8th Survey

2019 ◽  
Vol 58 (06) ◽  
pp. 425-433 ◽  
Author(s):  
Oliver Lindner ◽  
Wolfgang Burchert ◽  
Ronny Buechel ◽  
Wolfgang Michael Schäfer ◽  
Keyword(s):  
Myocardial Perfusion ◽  
Gated Spect ◽  
Stress Test ◽  
Myocardial Perfusion Spect ◽  
Positive Development ◽  
University Hospitals ◽  
Pharmacological Stress ◽  
Perfusion Spect ◽  
Pharmacological Stress Test ◽  
Current Guidelines

Abstract Aim This paper presents the results of the 8th survey of myocardial perfusion SPECT (MPS) from the reporting year 2018. Methods 291 questionnaires (184 practices (PR), 77 hospitals (HO), 30 university hospitals (UH)) were evaluated. Results of the last survey from 2015 are set in squared brackets. Results MPS of 145 930 [121 939] patients were reported (+ 19.6 %). 76 % [78 %] of all patients were studied in PR, 16 % [14 %] in HO, and 8 % [8 %] in UH, mostly with a 2-day-protocol 48 % [50 %]. 99.96 % [98 %] of all MPS were performed with Tc-99 m radiopharmaceuticals and in 0.04 % with Tl-201.A pharmacological stress test was applied in 49 % [43 %] (23 % [22 %] adenosine, 26 % [20 %] regadenoson, dipyridamole or dobutamine together < 1 % [1 %]). Attenuation correction was performed in 26 % [25 %] of all MPS, gated SPECT in 86 % [80 %] of stress MPS, in 87 % [78 %] of rest and in 83 % [76 %] of all stress and rest MPS. 67 % [53 %] of the departments performed MPS scoring by default, whereas 16 % [24 %] did not apply this feature at all.69 % [60 %] reported an increase or no changes in their MPS patient numbers. One hundred twenty-six departments which participated in the surveys from 2009 to 2018 reported an increase in MPS by 44 %. 69 % [70 %] of the MPS were requested by ambulatory care cardiologists. Conclusion The 2018 MPS survey reveals a high-grade adherence of routine MPS practice to current guidelines. The positive development in MPS performance and MPS numbers observed since 2012 remains ongoing.

scholarly journals Myocardial perfusion SPECT 2015 in Germany

2017 ◽  
Vol 56 (01) ◽  
pp. 31-38 ◽  
Author(s):  
Wolfgang Burchert ◽  
Wolfgang Schäfer ◽  
Marcus Hacker ◽  
Oliver Lindner
Keyword(s):  
Nuclear Medicine ◽  
Myocardial Perfusion ◽  
Stress Test ◽  
Myocardial Perfusion Spect ◽  
German Society ◽  
Positive Trend ◽  
University Hospitals ◽  
Educational Training ◽  
Pharmacological Stress ◽  
Perfusion Spect

SummaryAim: The working group Cardiovascular Nuclear Medicine of the German Society of Nuclear Medicine presents the results of the 7th survey of myocardial perfusion SPECT (MPS) of the reporting year 2015. Method: 268 guestionnaires (173 practices [PR], 67 hospitals [HO], 28 university hospitals ]UH[) were evaluated. Results of the last survey from 2012 are set in sguared brackets. Results: MPS of 121939 [105941] patients were reported. 98% [95 %] of all MPS were performed with Tc-99m radiopharmaceuticals and 2 % [5 %] with TI-201.78% [79%] of all patients were studied in PR, 14% [15%] in HO, and 8% [6%] in UH. A pharmacological stress test was performed in 43% [39%] (22 % [24 %] adenosine, 20 % [9 %] regade- noson, 1 % [6 %] dipyridamole or dobutamine). Attenuation correction was applied in 25 % [2009: 10 %] of MPS. Gated SPECT was performed in 78 % [70 %] of all rest MPS, in 80 % [73 %] of all stress and in 76 % [67 %] of all stress and rest MPS. 53 % [33 %] of all nuclear medicine departments performed MPS scoring by default, whereas 24% [41 %] did not apply any quantification. 31 % [26 %] of all departments noticed an increase in their counted MPS and 29% [29%] no changes. Data from 89 departments which participated in all surveys showed an increase in MPS count of 11.1 % (PR: 12.2 %, HO: 4.8%, UH: 18.4%). 70 % [60 %] of the MPS were reguested by ambulatory care cardiologists. Conclusion: The 2015 MPS survey reveals a high-grade adherence of routine MPS practice to current guidelines. The positive trend in MPS performance and number of MPS already observed in 2012 continues. Educational training remains necessary in the field of SPECT scoring.

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