The Relation between Staphylocoagulase Reacting Factor and Proteins Induced by Vitamin K Absence

1975 ◽  
Author(s):  
B. M. Bas ◽  
A. D. Muller ◽  
H. G. Hemker
Keyword(s):  
Vitamin K ◽  
Vitamin K Antagonists ◽  
The Other ◽  
Two Stage ◽  
One Stage ◽  
Echis Carinatus ◽  
The Difference ◽  
The One ◽  
Factor Assay

Five different ways of estimating prothrombin are applied to the plasma of persons receiving vitamin K antagonists, to know: the one-stage assay, the two-stage assay, the Echis Carinatus Venom assay, the coagulase-reacting factor assay and the immunological assay. The Protein Induced by Vitamin K Absence analogous to prothrombin (PIVKA-II) can be shown to be co-estimated in all but the one-stage assay. There are minor differences, however, between the other four tests. The most practical way to assess both prothrombin and PIVKA-II seems to be the coagulase-reacting factor assay. The difference between the one-stage assay and the others can be explained on basis of the new data on the role of vitamin K in prothrombin biosynthesis. The differences between the other tests are smaller and remain to be explained.

scholarly journals The role of focus marking in disjunctive questions: A QUD-based approach

2021 ◽  
Vol 30 ◽  
pp. 654
Author(s):  
Morwenna Hoeks
Keyword(s):  
The Other ◽  
Congruence Condition ◽  
Contrastive Topic ◽  
Structural Differences ◽  
Alternative Questions ◽  
The Difference ◽  
The One ◽  
The Right ◽  
Focus Marking

Disjunctive questions are ambiguous: they can either be interpreted as polar questions (PolQs), as open disjunctive questions (OpenQs), or as closed alternative questions (ClosedQ). The goal of this paper is to show that the difference in interpretation between these questions can be derived via effects of focus marking directly. In doing so, the proposal brings out the striking parallel between the prosody of questions with foci/contrastive topics on the one hand and that of alternative questions on the other. Unlike previous approaches, this proposal does not rely on structural differences between AltQs and PolQs derived via ellipsis or syntactic movement. To show how this works out, an account of focus and contrastive topic marking in questions is put forward in which f-marking in questions determines what constitutes a possible answer by signaling what the speaker's QUD is like. By imposing a congruence condition between f-marked questions and their answers that requires answers to resolve the question itself as well as its signaled QUD, we predict the right answerhood conditions for disjunctive questions.

The role of language in television news violence

1991 ◽  
Vol 14 (1) ◽  
pp. 3-16
Author(s):  
Paul Paridaen
Keyword(s):  
Television News ◽  
The Other ◽  
News Stories ◽  
The Difference ◽  
The One

Abstract This paper analyzes the role of language in the perception of violence in television news stories. 240 people were asked to watch and/or listen to news stories and then to record their perception of the information. The difference between perceived violence from pictures only on the one hand, and spoken narrative with or without pictures on the other, was highly significant, indicating that the spoken narrative was responsible for the perception of violence in the stories.

scholarly journals A Note on the Role of Mean Flows in Doppler-Shifted Frequencies

2013 ◽  
Vol 43 (2) ◽  
pp. 432-441 ◽  
Author(s):  
Theo Gerkema ◽  
Leo R. M. Maas ◽  
Hans van Haren
Keyword(s):  
Doppler Shift ◽  
Wave Dispersion ◽  
The Other ◽  
Mean Flow ◽  
Fixed Position ◽  
Doppler Shifts ◽  
The Mean ◽  
The Difference ◽  
The One

Abstract The purpose of this paper is to resolve a confusion that may arise from two quite distinct definitions of “Doppler shifts”: both are used in the oceanographic literature but they are sometimes conflated. One refers to the difference in frequencies measured by two observers, one at a fixed position and one moving with the mean flow—here referred to as “quasi-Doppler shifts.” The other definition is the one used in physics, where the frequency measured by an observer is compared to that of the source. In the latter sense, Doppler shifts occur only if the source and observer move with respect to each other; a steady mean flow alone cannot create a Doppler shift. This paper rehashes the classical theory to straighten out some misconceptions. It is also discussed how wave dispersion affects the classical relations and their application.

scholarly journals (Re)conceptualizing Difference in the Context of the Acting Subject’s Identity

2021 ◽  
Vol 13 (2) ◽  
pp. 88-108
Author(s):  
Anna Walczak
Keyword(s):  
Jacques Derrida ◽  
The Other ◽  
Social Discourse ◽  
Main Theme ◽  
Other Hand ◽  
The Subject ◽  
The Difference ◽  
The One

What is the source and the effect of the acting subject’s identity? This question refers to difference, but not in its usual conceptualization, synonymous with a border and the need to maintain or transcend it. By reconceptualizing difference, which I see as “re-creating” the meaning and linking it with “added” meanings, this article restores its original load (importance) in being an acting subject, mediated in otherness. For this purpose, the différance of Jacques Derrida is invoked and his statements about it combined with those of other philosophers, in whom I found what is related and/or complementary and extends not only Derrida's thought, but that which constitutes the main theme of this article. On the one hand, otherness is an impulse to the “work” of the difference, and on the other hand, it is its effect. What is the role of the “work” of the difference in creating the identity of the acting subject? In connection with the “shift” of the effect of its work – otherness, into the area of the identity of the acting subject, can this subject say about itself: this is still me? In this context, what is responsive ethics, which, I believe, should be included in the contemporary humanistic and social discourse about the subject?

4. Asking Questions: How to Find and Formulate Research Questions

2020 ◽  
pp. 93-122
Author(s):  
Sandra Halperin ◽  
Oliver Heath
Keyword(s):  
Literature Review ◽  
Research Question ◽  
Research Process ◽  
The Other ◽  
General Question ◽  
Asking Questions ◽  
Research Questions ◽  
The Difference ◽  
The One

This chapter deals with the first step of the research process: the formulation of a well-crafted research question. It explains why political research should begin with a research question and how a research question structures the research process. It discusses the difference between a topic or general question, on the one hand, and a focused research question, on the other. It also considers the question of where to find and how to formulate research questions, the various types of questions scholars ask, and the role of the ‘literature review’ as a source and rationale for research questions. Finally, it describes a tool called the ‘research vase’ that provides a visualization of the research process, along with different types of questions: descriptive, explanatory, predictive, prescriptive, and normative.

4. Asking Questions

2017 ◽  
Author(s):  
Sandra Halperin ◽  
Oliver Heath
Keyword(s):  
Research Question ◽  
Research Process ◽  
The Other ◽  
General Question ◽  
Different Types ◽  
Asking Questions ◽  
Research Questions ◽  
The Difference ◽  
The One

This chapter deals with the first step of the research process: the formulation of a well-crafted research question. It explains why political research should begin with a research question and how a research question structures the research process. It discusses the difference between a topic or general question, on the one hand, and a focused research question, on the other. It also considers the question of where to find and how to formulate research questions, the various types of questions scholars ask, and the role of the ‘literature review’ as a source and rationale for research questions. Finally, it describes a tool called the ‘research vase’ that provides a visualization of the research process, along with different types of questions: descriptive question, explanatory question, predictive question, prescriptive question and normative question.

scholarly journals Crowdsourcing: A Critical Discussion on Some Issues of a Challenging New Practice in the Digitization of Photographic Heritage

2016 ◽  
Vol 42 ◽  
Author(s):  
Jan Baetens
Keyword(s):  
Belief Systems ◽  
Critical Discussion ◽  
The Other ◽  
Photographic Material ◽  
Other Hand ◽  
Creative Tension ◽  
The Difference ◽  
The One

This article deals with a certain number of issues raised by the use of crowdsourcing in the management of photographic archives. Although crowdsourcing is (and should remain) a vital instrument in the description and analysis of photographic material, it does not really take into account certain problems such as the difference between information and knowledge, the reduction of knowledge to merely cognitive elements (at the expense of social, political, and ideological belief systems) and the creative tension between the unique artefact on the one hand and serialization on the other hand. Relying on the work by Yves Citton and his plea for the role of interpretation in humanist research, this article will offer a new way of "framing" the technique of crowdsourcing in a larger interpretive context.

scholarly journals Tense morphology and verb-second in Swedish L1 children, L2 children and children with SLI

2001 ◽  
Vol 4 (1) ◽  
pp. 85-99 ◽  
Author(s):  
Gisela Håkansson
Keyword(s):  
Language Impairment ◽  
Specific Language Impairment ◽  
The Other ◽  
Intermediate Step ◽  
Verb Second ◽  
Specific Language ◽  
Significant Difference ◽  
The Difference ◽  
The One

This paper compares the development of tense morphology and verb-second in different learner populations. Three groups of Swedish pre-school children are investigated longitudinally; ten L1 children, ten L2 children and ten children diagnosed with Specific Language Impairment (SLI). Data was collected twice, with an interval of six months. The results at Time I reveal a significant difference between normally developing L1 children on the one hand and L2 children and children with SLI on the other. The L1 children use verb-second correctly in topicalized declaratives, whereas both L2 children and children with SLI use structures with the verb in third position (XSV structures) as an intermediate step towards verb-second. There is a clear development between the two data collection sessions for the L2 children and the children with SLI, diminishing the difference between them and the unimpaired L1 children. The similarity that is found between L2 children and children with SLI in this study bears important implications for the discussion of the role of transfer in L2 research and for the question of a defective linguistic representation in SLI research.

A Tentative Cause of Discrepancy Between FVIII:C Estimation

1979 ◽  
Author(s):  
M.J. Seghatchian
Keyword(s):  
Molecular Size ◽  
Molecular Forms ◽  
Factor X ◽  
Two Stage ◽  
One Stage ◽  
Preferential Adsorption ◽  
The One ◽  
Molecular Nature ◽  
Similar Peak

Biochemical analysis based on the molecular size and change was performed on normal, patient plasmas and clinical concentrate to differentiate various molecular forms of FVIII:C. Assay of the effluent fractions by one stage, two stage and chromogenic methods revealed two major peaks of activities, measured to differing extents by various methods. Thromboplastin generation methods (two stage clotting and chromogenic) were particularly sensitive to smaller forms, which had a faster electrophoresis mobility and eluted in the gamma globulin region. The one stage method measured mainly the aggregated forms (MW> 300.000), with the slower electrophoretic mobility.A discrepancy of about 30% between the two methods could account for the detection of the smaller form, which predominated in plasma rather than concentrate. This had a preferential adsorption on Al(OH)3 and some FVIII.C neutralising activity. A similar peak of activity was identified in haemophilia and V.Wd. plasma isolated on sepharose suggesting that the whole plasma contained an inhibitory factor acting on the clotting activity. Excess factor X and traces or thrombin-like enzymes could be identified in this region. Thus the role of these factors in accelerating the rate of FXa generation by activating FVIII can not be excluded.Regardless of the molecular nature of this form of FVIII, this activity may play an important role in controlling haemstasis via VIII activation and may explain the discrepancy between assay of plasma versus concentrate.

The Formation of Intermediate Product I in a Purified System The Role of Factor IX or of its Precursor and of a Hageman Factor-PTA Fraction

1961 ◽  
Vol 6 (02) ◽  
pp. 224-234 ◽  
Author(s):  
E. T Yin ◽  
F Duckert
Keyword(s):  
Intermediate Product ◽  
Factor Ix ◽  
Assay Method ◽  
Lag Phase ◽  
Factor X ◽  
Haemophilia B ◽  
Hageman Factor ◽  
One Stage ◽  
The One

Summary1. The role of two clot promoting fractions isolated from either plasma or serum is studied in a purified system for the generation of intermediate product I in which the serum is replaced by factor X and the investigated fractions.2. Optimal generation of intermediate product I is possible in the purified system utilizing fractions devoid of factor IX one-stage activity. Prothrombin and thrombin are not necessary in this system.3. The fraction containing factor IX or its precursor, no measurable activity by the one-stage assay method, controls the yield of intermediate product I. No similar fraction can be isolated from haemophilia B plasma or serum.4. The Hageman factor — PTA fraction shortens the lag phase of intermediate product I formation and has no influence on the yield. This fraction can also be prepared from haemophilia B plasma or serum.

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