scholarly journals Thiopyridone-Derived Reagents for Peptide Coupling Reactions

Synfacts ◽  
2021 ◽  
Vol 17 (05) ◽  
pp. 0587
Keyword(s):  
Coupling Reactions ◽  
Peptide Coupling

Total syntheses of smenothiazoles A and B

2017 ◽  
Vol 15 (34) ◽  
pp. 7196-7203 ◽  
Author(s):  
Xiao Ma ◽  
Yajie Chen ◽  
Sigui Chen ◽  
Zhengshuang Xu ◽  
Tao Ye
Keyword(s):  
Total Synthesis ◽  
Vinyl Chloride ◽  
Coupling Reactions ◽  
Stille Reaction ◽  
Total Syntheses ◽  
Peptide Coupling ◽  
Diene System

Stereocontrolled installation of vinyl chloride and the 2,5-diene system via silastannation, Stille reaction and desilylchlorination, and the final peptide coupling reactions led to the concise total synthesis of smenothiazoles A (1) and B (2).

Glycolamide esters of N-acylamino acids and peptides

1965 ◽  
Vol 18 (7) ◽  
pp. 1089 ◽  
Author(s):  
FHC Stewart
Keyword(s):  
Peptide Synthesis ◽  
Coupling Reactions ◽  
Peptide Coupling ◽  
Model Experiments ◽  
Mild Conditions

The glycolamide esters, RNHCHR'CO2CH2CONH2, of several N-acylamino acids have been prepared. Model experiments indicate that the glycolamide group possesses weak acylating ability in simple peptide coupling reactions, but that it can be dehydrated under mild conditions with formation of cyanomethyl esters, which are known to be active acylating agents. The possible application of the glycolamide derivatives in peptide synthesis is considered. A number of protected dipeptide glycolamide esters were also synthesized.

Enhancement of peptide coupling reactions by 4-dimethylaminopyridine

2009 ◽  
Vol 18 (5) ◽  
pp. 459-467 ◽  
Author(s):  
S.S. Wang ◽  
J.P. Tam ◽  
B.S.H. Wang ◽  
R.B. Merripield
Keyword(s):  
Coupling Reactions ◽  
Peptide Coupling
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