scholarly journals A Rare Case of Bilateral Tubal Ectopic Pregnancy Following Intracytoplasmic Sperm Injection-Embryo Transfer (ICSI-ET)

2020 ◽  
Vol 42 (03) ◽  
pp. 165-168
Author(s):  
Ferruh Acet ◽  
Ege Nazan Tavmergen Goker ◽  
Ismet Hortu ◽  
Gulnaz Sahin ◽  
Erol Tavmergen
Keyword(s):  
Ectopic Pregnancy ◽  
Embryo Transfer ◽  
Tubal Pregnancy ◽  
Serum Progesterone ◽  
Tubal Ectopic Pregnancy ◽  
Vitro Fertilization ◽  
Reproductive Techniques ◽  
History Of ◽  
Β Hcg

AbstractBilateral tubal ectopic pregnancy is a very rare form of ectopic pregnancy. The incidence is higher in women undergoing assisted reproductive techniques or ovulation induction. We report the case of bilateral tubal ectopic pregnancy. The patient was 30 years old and had a 3-year history of infertility; she was referred to the in-vitro fertilization (IVF) program because of tubal factor infertility. A pregnancy resulted from the transfer of two embryos during an artificial cycle. Despite the increase in β-hCG values during the follow-up, 22 days after the embryo transfer, the β-hCG levels were 2,408 U/L and the serum progesterone (P4) level was 10.53 ng/ml. After application with methotrexate, β-hCG levels did not decrease effectively. Moreover, the sonographic screening revealed a suspicious bilateral tubal focus for ectopic pregnancy. A mini-laparotomy was performed and a bilateral tubal pregnancy was found. In the case of unilateral tubal pregnancy after the transfer of two embryos, the situation of the other tube should be systematically checked and β-hCG levels should be monitored.

scholarly journals Luteal phase serum progesterone level as a predictor of vaginal bleeding or adverse pregnancy outcome in patients undergoing assisted reproductive techniques

2018 ◽  
Vol 7 (8) ◽  
pp. 3152
Author(s):  
Ashish Kale ◽  
Ashwini Kale
Keyword(s):  
Pregnancy Outcome ◽  
Embryo Transfer ◽  
Vaginal Bleeding ◽  
Adverse Pregnancy Outcome ◽  
Progesterone Level ◽  
Serum Progesterone ◽  
Vitro Fertilization ◽  
Reproductive Techniques ◽  
Adverse Pregnancy

Background: With advances in assisted reproductive techniques its becoming increasingly important to identify pregnancies having a potential of adverse outcome in the form of per vaginal bleeding or early pregnancy loss. The objective of this study was to find out whether the value of luteal phase progesterone can be used as a marker to predict the possibility of per vaginal bleeding and early pregnancy loss in cases conceived by in vitro fertilization (IVF) and embryo transfer (ET).Methods: A total of 40 women of age less than or equal to 40 years undergoing IVF and ET were included in this study depending upon inclusion criteria. Patients were excluded if they had any factor defined as exclusion criteria. on D14 after embryo transfer B-hCG was done in all the patients. If B-hCG levels were found to be ≥ 100 mIU/ml then serum progesterone levels were also done. B-hCG levels were repeated after 48 hours. Pregnancies were followed up and correlation between suboptimal rise in serum progesterone levels and adverse pregnancy outcome was studied.Results: Mean Beta-hCG and Serum progesterone levels on D14 of embryo transfer were found to be 388.86±34 mIU/ml and 54.24±4.32 ng/ml respectively. A repeat B-hCG and serum progesterone level 48 hours after initial estimation showed mean B-hCG and serum progesterone level to be 598.80±52.12 mIU/ml and 72. 24±5.24 ng/ml respectively. Out of 40 patients 26 patients showed >30% rise in serum progesterone level while 14 patients showed less than 30% rise in serum progesterone level.Conclusions: Suboptimal rise in serum progesterone level (<30%) was associated with increased incidence of adverse pregnancy outcome in women conceived after in vitro fertilization and embryo transfer.

scholarly journals Abdominal ectopic pregnancy following a frozen embryo transfer cycle: a case report

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Yan Li ◽  
Jiaxuan Geng ◽  
Qiaohua He ◽  
Jin Lu ◽  
Jin Xu ◽  
...  
Keyword(s):  
Early Diagnosis ◽  
Ectopic Pregnancy ◽  
Embryo Transfer ◽  
Close Monitoring ◽  
Case Presentation ◽  
Vitro Fertilization ◽  
Β Hcg ◽  
Frozen Thawed Embryo Transfer ◽  
Artificial Cycle

Abstract Background Abdominal ectopic pregnancy (AEP) is a rare form of ectopic pregnancy. As the number of in-vitro fertilization (IVF) procedures continues to increase, the incidence of AEP will also rise. However, the rarity and atypical presentation of AEP make early diagnosis challenging. Case presentation Herein, we report an AEP following frozen-thawed embryo transfer (FET) in an artificial cycle. The patient was misdiagnosed with implantation failure when the serum human chorionic gonadotropin (hCG) level was detected as 2.59mIU/ml at fourteenth day after embryo transfer. Therefore, she was suggested to stop luteal phase support. However, a ruptured AEP was developed 33 days following embryo transfer, which was diagnosed by laparoscopic surgery. Conclusions The case highlighted the delayed serum β-hCG and massive intraperitoneal hemorrhage may be clues to make early diagnosis of AEP. Clinicians must attach great importance to close monitoring and bear in mind the possibility of abdominal pregnancy.

scholarly journals Spontaneous pregnancy following post in vitro fertilization ruptured tubal ectopic pregnancy

2020 ◽  
Vol 9 (11) ◽  
pp. 4738
Author(s):  
Kirty Nahar ◽  
Nikita Nahar
Keyword(s):  
In Vitro Fertilization ◽  
Ectopic Pregnancy ◽  
Polycystic Ovary ◽  
Exploratory Laparotomy ◽  
Assisted Reproductive Techniques ◽  
Obstetric Outcome ◽  
Tubal Ectopic Pregnancy ◽  
Vitro Fertilization ◽  
Reproductive Techniques

Ectopic pregnancy (EP) is a dramatic life threatening event in a woman’s reproductive life, especially after a long, expensive and difficult course of treatment for infertility. EP accounts around 1–2% of all natural conceptions, and this prevalence increases following assisted reproductive techniques, to range between 2.1% and 8.6% and it can reach up to 11% in women with tubal factors infertility history. A 32 year old female, primigravida presented at emergency department of Apollo Hospitals, Ahmedabad with complaints of amenorrhoea 2 months, severe pain abdomen associated with vomiting, difficulty in breathing and bleeding per vagina on and off. She was a case of primary infertility with polycystic ovary syndrome (PCOS) who had conceived after difficulty with in vitro fertilization (IVF), resulted in ruptured right tubal ectopic pregnancy. She underwent exploratory laparotomy followed by removal of right ectopic pregnancy, right salpingectomy and peritoneal lavage. Early diagnosis, timely intervention and prompt surgical management could save the patient’s life. Later on she conceived spontaneously and had an eventful and complicated pregnancy. She presented at 35 weeks of pregnancy with preterm labour pain and underwent emergency caesarean section for fetal distress. She delivered a healthy male child and had a successful obstetric outcome. Diagnosis of ruptured tubal ectopic pregnancy is made based on patient’s history, clinical acumen, serum beta human chorionic gonadotropin (hCG) levels and pelvic ultrasound. Ectopic pregnancy should be suspected in patients with an adnexal mass even in absence of risk factors. Clinicians must be alert to the fact that assisted reproductive techniques as a treatment for infertility can result into ectopic pregnancy. This case highlights the fact that patient who underwent IVF treatment resulting in ruptured tubal ectopic pregnancy can have spontaneous conception and a successful obstetric outcome.

Unilateral triplet ectopic pregnancy after in vitro fertilization and embryo transfer

2008 ◽  
Vol 90 (5) ◽  
pp. 2003.e17-2003.e20 ◽  
Author(s):  
Eniko Berkes ◽  
Gyorgy Szendei ◽  
Laszlo Csabay ◽  
Zsuzsanna Sipos ◽  
Jozsef Gabor Joo ◽  
...  
Keyword(s):  
In Vitro Fertilization ◽  
Ectopic Pregnancy ◽  
Embryo Transfer ◽  
Vitro Fertilization
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