Abdominal ectopic pregnancy following a frozen embryo transfer cycle: a case report

Abstract Background Abdominal ectopic pregnancy (AEP) is a rare form of ectopic pregnancy. As the number of in-vitro fertilization (IVF) procedures continues to increase, the incidence of AEP will also rise. However, the rarity and atypical presentation of AEP make early diagnosis challenging. Case presentation Herein, we report an AEP following frozen-thawed embryo transfer (FET) in an artificial cycle. The patient was misdiagnosed with implantation failure when the serum human chorionic gonadotropin (hCG) level was detected as 2.59mIU/ml at fourteenth day after embryo transfer. Therefore, she was suggested to stop luteal phase support. However, a ruptured AEP was developed 33 days following embryo transfer, which was diagnosed by laparoscopic surgery. Conclusions The case highlighted the delayed serum β-hCG and massive intraperitoneal hemorrhage may be clues to make early diagnosis of AEP. Clinicians must attach great importance to close monitoring and bear in mind the possibility of abdominal pregnancy.

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Serum progesterone and estradiol concentrations in the early diagnosis of ectopic pregnancy after in vitro fertilization-embryo transfer

Fertility and Sterility ◽

10.1016/s0015-0282(16)55818-x ◽

1993 ◽

Vol 59 (3) ◽

pp. 668-670 ◽

Cited By ~ 10

Author(s):

Maria Bustillo ◽

J. Jaroslav Stern ◽

Dixie King ◽

Carolyn B. Coulam

Keyword(s):

In Vitro Fertilization ◽

Early Diagnosis ◽

Ectopic Pregnancy ◽

Embryo Transfer ◽

Serum Progesterone ◽

Vitro Fertilization

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A Rare Case of Bilateral Tubal Ectopic Pregnancy Following Intracytoplasmic Sperm Injection-Embryo Transfer (ICSI-ET)

Revista Brasileira de Ginecologia e Obstetrícia / RBGO Gynecology and Obstetrics ◽

10.1055/s-0040-1708093 ◽

2020 ◽

Vol 42 (03) ◽

pp. 165-168

Author(s):

Ferruh Acet ◽

Ege Nazan Tavmergen Goker ◽

Ismet Hortu ◽

Gulnaz Sahin ◽

Erol Tavmergen

Keyword(s):

Ectopic Pregnancy ◽

Embryo Transfer ◽

Tubal Pregnancy ◽

Serum Progesterone ◽

Tubal Ectopic Pregnancy ◽

Vitro Fertilization ◽

Reproductive Techniques ◽

History Of ◽

Β Hcg

AbstractBilateral tubal ectopic pregnancy is a very rare form of ectopic pregnancy. The incidence is higher in women undergoing assisted reproductive techniques or ovulation induction. We report the case of bilateral tubal ectopic pregnancy. The patient was 30 years old and had a 3-year history of infertility; she was referred to the in-vitro fertilization (IVF) program because of tubal factor infertility. A pregnancy resulted from the transfer of two embryos during an artificial cycle. Despite the increase in β-hCG values during the follow-up, 22 days after the embryo transfer, the β-hCG levels were 2,408 U/L and the serum progesterone (P4) level was 10.53 ng/ml. After application with methotrexate, β-hCG levels did not decrease effectively. Moreover, the sonographic screening revealed a suspicious bilateral tubal focus for ectopic pregnancy. A mini-laparotomy was performed and a bilateral tubal pregnancy was found. In the case of unilateral tubal pregnancy after the transfer of two embryos, the situation of the other tube should be systematically checked and β-hCG levels should be monitored.

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Fresh Autologous In Vitro Fertilization is Associated with Increased Incidence of Ectopic Pregnancy when Compared with Oocyte Donation and Frozen-Thawed Embryo Transfer Cycles

Fertility and Sterility ◽

10.1016/j.fertnstert.2010.01.026 ◽

2010 ◽

Vol 93 (5) ◽

pp. S5-S6

Author(s):

B.S. Shapiro ◽

S.T. Daneshmand ◽

F.C. Garner ◽

M. Aguirre ◽

C. Hudson ◽

...

Keyword(s):

In Vitro Fertilization ◽

Ectopic Pregnancy ◽

Embryo Transfer ◽

Oocyte Donation ◽

Vitro Fertilization ◽

Frozen Thawed Embryo Transfer ◽

Thawed Embryo Transfer

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Administration of oxytocin antagonist at the same time as using a Foley catheter with cotton swab before embryo transfer for cervical stenosis

BMC Women s Health ◽

10.1186/s12905-021-01409-y ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Heesuk Chae

Keyword(s):

Embryo Transfer ◽

Foley Catheter ◽

Cervical Canal ◽

Cervical Stenosis ◽

Cotton Swab ◽

Case Presentation ◽

Vitro Fertilization ◽

Oxytocin Antagonist ◽

Frozen Thawed Embryo Transfer

Abstract Background Embryo transfer without difficulty in a patient with cervical stenosis can be a great challenge for in vitro fertilization (IVF). We report a successful pregnancy following a frozen thawed embryo transfer after administration of an oxytocin antagonist at the same time as using a Foley catheter with cotton swab in a patient with refractory cervical stenosis. Case presentation A 40-year-old woman undergoing IVF. The patient’s previous embryo transfers were difficult. For every transfer, uterine manipulation was needed, force was required, and dilatation was necessary. A Foley catheter with a cotton swab was inserted into the cervical canal, atosiban was administered at the same time, and the Foley catheter was removed immediately before embryo transfer. A smooth transfer was performed without bleeding, force, uterine manipulation, or cervical dilator. The patient became pregnant and delivered by cesarean section at term. Conclusion This method is effective in performing atraumatic embryo transfer in patients with cervical stenosis.

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