Left Atrial Myxoma and Antiphospholipid Syndrome—A Case Report

Author(s):  
Mijo Meter ◽  
Diana Meter ◽  
Toni Ceprnja ◽  
Dijana Perkovic

AbstractCardiac myxoma (CM) is the most frequent type of primary cardiac neoplasm and is responsible for 58 to 80% of primary cardiac tumors. The antiphospholipid syndrome (APS) occurs most commonly in the systemic lupus erythematosus but it can be also found in other conditions. The coexistence of CM and APS is rarely described in the literature. We report an unusual case of the left atrial myxoma and concomitant APS in a female patient who presented with right-sided hemiplegia. Although rare, we must think about the CM in patients with a newly diagnosed APS and left atrial mass. Nevertheless, we must make a distinction from other possible cardiac structures, especially atrial thrombus. Transthoracic echocardiography is the most frequently used initial imaging modality to detect CM. The aim of this case report was to emphasize that additional imaging modalities and multidisciplinary approach are mandatory in making a proper diagnosis and to choose a further treatment strategy.

Pulse ◽  
2018 ◽  
Vol 10 (1) ◽  
pp. 29-33
Author(s):  
T Meher ◽  
SMAZN Palash ◽  
MK Hasan ◽  
TMNS Khan ◽  
NM Zahangir ◽  
...  

Atrial Myxoma is the most common primary cardiac tumors accounting for about 50% of benign primary cardiac tumors, with the majority located in the left atrium. This is a case of large left atrial (LA) myxoma presented with features of mitral stenosis associated with moderate left ventricular failure (LVF) and mild pulmonary artery hypertension (PAH) The patient improved markedly after tumor excision.Pulse Vol.10 January-December 2017 p.29-33


2021 ◽  
Author(s):  
Leonardo Daniel Reis Santos ◽  
Omar Pereira de Almeida Neto ◽  
Michelle Franco Macedo de Lima ◽  
Nathália Varano

Context: Cardiac tumors are rare and myxomas are the most prevalent between them. Although histologically benign, they may cause severe effects given their intracardiac location. Unspecific symptoms compromise the diagnosis, leading to complications such as changes in the cerebral vascular dynamics. Case report following the CARE guidelines. Case report: A 62-year-old woman was admitted to a high complexity hospital in Minas Gerais, with history of unstable angina, aphasia, right hemiparesis, dysarthria, claiming precordialgia with strong intensity. Complained hyporexia and weight loss during the last month. Medical history of 7 transient ischemic attacks (TIA) in the last two years. Physical examination with no abnormalities. Chest x-ray and transesophageal echocardiogram showed bilateral neovascularization and 4.9 x 2.9 cm dimension mass in the left atrium. Coronary angiography revealed proximal calcification and atherosclerotic plaque occluding 40% of the flux in the middle third of the anterior descending artery, pointing to the coexistence of coronary disease and left atrial myxoma. The occurrence of a TIA was determined and the prescription of an anticoagulant to avoid future embolic events. A surgical approach was necessary. Biopsy concluded myxoid and hyaline-rich stroma tumor, evident vascular system, star-shaped cells isolated or forming small groups, confirming myxoma diagnosis. After a ten-day hospitalization, the patient was clinically stable, and was discharged after health education. Conclusion: Cardiac tumors such as myxomas lead to important cerebral vascular consequences, so that the clinical investigation is essential to the differential diagnosis between a stroke and the TIA, to provide adequate treatment and disease prevention.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Sadegh Shabab ◽  
Majid Erfanzadeh ◽  
Shamsa Ahmadian ◽  
Maryam Mahmoudabady ◽  
Naser Mazloum

Abstract Background Primary cardiac tumors are rare, and approximately 90% of them are benign. Myxoma is the most common type of these tumors occurring in the left atrium in 75–85% of cases. The tumor can cause the left atrio-ventricular valve obstruction and embolization phenomenon. Case presentation We reported a case of 54-year-old man with complaints of dyspenea and amnesia. In our patient, transthoracic echocardiography revealed a mass of 28*63 mm attached to the upper intra-atrial septum, which was prolapsing through the mitral valve into the left ventricle during diastole, being indicative of the left atrial myxoma. On examination, he was alert and conversant, and no pathological abnormality was observed in the examination of cardiovascular, gastrointestinal, respiratory, hepatic, renal and nervous systems. After myxoma diagnosis, the tumor was removed under cardiac surgery and discharged under good conditions. In the telephone follow-up after discharge, the patient recovered and did not report the disease and surgery complications. Conclusions Patients with cardiac myxoma are usually asymptomatic, but they may have manifestations related to the embolism phenomenon or intracardiac obstruction. Therefore, myxoma may represent an emergency. Surgery should be performed as soon as possible. If surgery is delayed, the patient may suffer from serious and irreversible complications, such as stroke and cardiac arrest.


2019 ◽  
pp. 1-3
Author(s):  
Shaima A Alanqari ◽  
Ahmed ElSayed Mahmoud ◽  
Ashwaq F. Alfaqeer ◽  
Fayaz aahmed

Benign cardiac myxoma with glandular differentiation is an extremely rare subtype of cardiac tumors which can mimic myxosarcoma grossly and histologically. Primary cardiac tumors are extremely rare and account for less than 0.2% of all tumors. They are benign in 75% of cases and almost 50% of these are myxomas. The differentiation between benign and malignant cardiac tumors is challenging by echocardiography or histologically. We report a case of primary left atrial benign cardiac myxoma mimicking myxosarcoma grossly and histologically by its glandular differentiation. Only 39 such cases reported in the literature.


2021 ◽  
Vol 27 (5) ◽  
pp. 572-582
Author(s):  
О. Yu. Korennova ◽  
I. V. Druk ◽  
S. N. Starinskaya ◽  
J. V. Tereshchenko ◽  
Yu. T. Ignatiev ◽  
...  

Myxoma of the heart is the most common variant of a primary benign heart tumor, which is complicated in some cases by embolic complications. Myxoma of the heart is often a diagnostic puzzle in young patients due to a low-symptom or masked clinical manifestations. This case report presents a 37-year-old patient with the onset of left atrial myxoma with mitral valve obstruction manifested with syncope, associated traumatic brain injury, rightsided hemihypesthesia, and speech difficulties. The examination showed multiple lacunar ischemic brain lesions in the middle cerebral artery basin. Transthoracic echocardiography (TTE) showed a large left atrial myxoma with prolapse into the left ventricle. Myxoma was successfully removed. The case highlights the complexity of the diagnosis of cardiac myxoma, associated with the variable clinical manifestations from low-symptomatic cases to the development of cardioembolic complications. Considering recurrent embolic complications, a quick identification of the causes of ischemic stroke in patients without cardiovascular risk factors is important. TTE is a highly specific and sensitive method for the diagnosis of cardiac myxoma. Surgery is a priority treatment method, characterized by a good prognosis for sporadic single-chamber isolated myxomas.


Author(s):  
Zhimin Liao ◽  
Weijiang Huang ◽  
Qi Hu ◽  
Ziyi Wang ◽  
Lei Pan ◽  
...  

2016 ◽  
Vol 2016 ◽  
pp. 1-3 ◽  
Author(s):  
Marcos Danillo Peixoto Oliveira ◽  
Adriano Ossuna Tamazato ◽  
Fernando Roberto de Fazzio ◽  
Luiz J. Kajita ◽  
Expedito E. Ribeiro ◽  
...  

Primary cardiac tumors are rare and approximately half of them are atrial myxomas. They rarely remain asymptomatic, especially if large. The imaging of a myxoma by contrast dye during coronary angiography is an infrequent sign, which clarifies the vascular supply of the tumor. We report herein an interesting and rare case of a left atrial myxoma hypervascularized from the right coronary artery.


2013 ◽  
Vol 163 (3) ◽  
pp. S90
Author(s):  
M. Ugurlu ◽  
B. Ekici ◽  
E.A. Ercan ◽  
A.F. Erkan ◽  
H.F. Tore

2016 ◽  
Vol 5 (98) ◽  
pp. 7213-7215
Author(s):  
Naba Kumar Pattnaik ◽  
Prasanna Kumar Mishra

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