Polymer impregnation vs. surface coating for targeted manipulation of biocompatibility and mechanical properties of xenogenic decellularized heart valves

2005 ◽  
Vol 53 (S 01) ◽  
Author(s):  
N Grabow ◽  
K Schmohl ◽  
A Kaminski ◽  
A Haubold ◽  
A Liebold ◽  
...  
Author(s):  
Sarah C. Vigmostad ◽  
Brian D. Jeffrey ◽  
Sreedevi Krishnan ◽  
H. S. Udaykumar ◽  
K. B. Chandran

Bioprosthetic heart valves are valve replacements constructed from animal tissue. They are deformable and offer similar mechanical properties to their native counterpart. While tearing of these valves is frequently observed, it is still not fully understood, but may be the result of high induced bending and shear stresses in the valve leaflets[1].


RSC Advances ◽  
2016 ◽  
Vol 6 (86) ◽  
pp. 83482-83492 ◽  
Author(s):  
Guangxiang Zhu ◽  
Shaoming Dong ◽  
Dewei Ni ◽  
Chengying Xu ◽  
Dengke Wang

SiCf/BNNTs–SiC hierarchical composites were fabricated via firstly in situ growth of BNNTs on SiC fibers using boron powder as a raw material and then matrix densification by chemical vapor infiltration and polymer impregnation/pyrolysis methods.


Author(s):  
F. I. Panteleenko ◽  
V. V. Zakharenko ◽  
M. V. Spetsian

The paper presents the results of experimental studies on the surface coating of powder EuTroLoy 16006.04 with the help of plasma-powder overlaying. Analysis of the macro-structure made it possible to establish a partial absence of pores, fusions and cracks between the sub-spoon and the deposited layer. Differences in the phase composition and in the mechanical properties of the coatings were established. In places of application of plasma-powder overlaying an increase in hardness has been revealed. 


2019 ◽  
Vol 9 (22) ◽  
pp. 4773 ◽  
Author(s):  
Evgeny Ovcharenko ◽  
Maria Rezvova ◽  
Pavel Nikishau ◽  
Sergei Kostjuk ◽  
Tatiana Glushkova ◽  
...  

Superior polymers represent a promising alternative to mechanical and biological materials commonly used for manufacturing artificial heart valves. The study is aimed at assessing poly(styrene-block-isobutylene-block-styrene) (SIBS) properties and comparing them with polytetrafluoroethylene (Gore-texTM, a reference sample). Surface topography of both materials was evaluated with scanning electron microscopy and atomic force microscopy. The mechanical properties were measured under uniaxial tension. The water contact angle was estimated to evaluate hydrophilicity/hydrophobicity of the study samples. Materials’ hemocompatibility was evaluated using cell lines (Ea.hy 926), donor blood, and in vivo. SIBS possess a regular surface relief. It is hydrophobic and has lower strength as compared to Gore-texTM (3.51 MPa vs. 13.2/23.8 MPa). SIBS and Gore-texTM have similar hemocompatibility (hemolysis, adhesion, and platelet aggregation). The subcutaneous rat implantation reports that SIBS has a lower tendency towards calcification (0.39 mg/g) compared with Gore-texTM (1.29 mg/g). SIBS is a highly hemocompatible material with a promising potential for manufacturing heart valve leaflets, but its mechanical properties require further improvements. The possible options include the reinforcement with nanofillers and introductions of new chains in its structure.


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