The incremental yield of endoscopic ultrasound over endobronchial ultrasound and CT for detection of extrathoracic metastases in lung cancer

Endoscopy ◽  
2006 ◽  
Vol 39 (S 1) ◽  
Author(s):  
J Conway ◽  
G Silvestri ◽  
C Reed ◽  
J Romagnuolo ◽  
R Hawes ◽  
...  
2017 ◽  
Vol 50 (5) ◽  
pp. 1701102 ◽  
Author(s):  
Paul Leong ◽  
Sheetal Deshpande ◽  
Louis B. Irving ◽  
Philip G. Bardin ◽  
Michael W. Farmer ◽  
...  

Endobronchial ultrasound transbronchial needle aspiration (EBUS TBNA) is an established, minimally invasive way to sample intrathoracic abnormalities. The EBUS scope can be passed into the oesophagus to perform endoscopic ultrasound with bronchoscope-guided fine-needle aspiration (EUS-B-FNA). In cases of suspected lung cancer, a combination of the two techniques is now recommended by consensus guidelines. EBUS TBNA is usually performed by pulmonologists; however, the learning curve for EUS-B-FNA, which may be performed during the same procedure, has not been described.A multicentre, observational Australian study, using prospectively collected data from three experienced pulmonologists was conducted. Cumulative sum (cusum) analysis was used to generate visual learning curves.A total of 152 target lesions were sampled in 137 patients, with an overall sensitivity for malignancy of 94.8%. The sensitivity for malignant lesions outside of the 2009 International Association for the Study of Lung Cancer lymph node map (largely intraparenchymal lesions) was 92.9%. All three operators were competent by conventional cusum criteria. There was one case of pneumothorax, and no episodes of mediastinitis or oesophageal perforation were observed.Our data suggest that experienced pulmonologists can safely and accurately perform EUS-B-FNA, with a high diagnostic sensitivity for both lymph node and non-nodal lesions.


2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
Koen Creemers ◽  
Olaf van der Heiden ◽  
Jan Los ◽  
Joost van Esser ◽  
David Newhall ◽  
...  

In recent years, endoscopic ultrasound techniques with Fine Needle Aspiration (FNA) have become an increasingly used diagnostic aid in the differentiation of mediastinal lymphadenopathy. Endobronchial ultrasound (EBUS) and endoesophageal ultrasound (EUS) are now available for clinicians to reach mediastinal and paramediastinal masses using a minimally invasive approach. These techniques are an established component for diagnosing and staging lung cancer and their benefit in the diagnosis of lymphoma's has been highlighted in a number of case studies. However, the lack of tissue architecture obtained by cytological FNA specimens decreases the diagnostic accuracy for benign causes of thoracic lymphadenopathies, lymphomas, and histopathological subtyping of lung cancer. Accordingly, our study group have adapted the FNA sampling technique, resulting in tissue fragments that can be used for histopathological examinations. As an illustration, we report a case of follicular non-Hodgkin lymphoma, diagnosed on tissue fragments obtained by adjusted EUS FNA. We believe that this relatively simple adjustment to routine FNA sampling can help to overcome the diagnostic limitations inherent in cytology obtained by routine FNA.


CHEST Journal ◽  
2007 ◽  
Vol 132 (4) ◽  
pp. 470B
Author(s):  
Michael B. Wallace ◽  
Jorge Pascual ◽  
Massimo Raimondo ◽  
Timothy A. Woodward ◽  
Barbara McComb ◽  
...  

2010 ◽  
Vol 42 (3) ◽  
pp. 157-162 ◽  
Author(s):  
Muhammad K. Hasan ◽  
Kanwar R.S. Gill ◽  
Michael B. Wallace ◽  
Massimo Raimondo

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