The Role and Place of Endoscopic Endonasal Transsphenoidal Technique in Pituitary Surgery

Skull Base ◽  
2009 ◽  
Vol 19 (01) ◽  
Author(s):  
Pavel Kalinin ◽  
Dmitry Fomichev ◽  
Boris Kadashev ◽  
Maxim Kutin ◽  
Ravshan Faizullaev ◽  
...  
2020 ◽  
Vol 47 (2) ◽  
pp. 227-232 ◽  
Author(s):  
Fumihiko Kuwata ◽  
Masahiro Kikuchi ◽  
Masaaki Ishikawa ◽  
Masahiro Tanji ◽  
Tatsunori Sakamoto ◽  
...  

2020 ◽  
Vol 28 ◽  
pp. 131-150
Author(s):  
Zhen Shen ◽  
Yi Xie ◽  
Xiuqin Shang ◽  
Gang Xiong ◽  
Shi Chen ◽  
...  

2014 ◽  
Vol 37 (5) ◽  
pp. E7 ◽  
Author(s):  
Nancy McLaughlin ◽  
Neil A. Martin ◽  
Pooja Upadhyaya ◽  
Ausaf A. Bari ◽  
Farzad Buxey ◽  
...  

Object Knowledge of the costs incurred through the delivery of neurosurgical care has been lagging, making it challenging to design impactful cost-containment initiatives. In this report, the authors describe a detailed cost analysis for pituitary surgery episodes of care and demonstrate the importance of such analyses in helping to identify high-impact cost activities and drive value-based care. Methods This was a retrospective study of consecutively treated patients undergoing an endoscopic endonasal procedure for the resection of a pituitary adenoma after implementation and maturation of quality-improvement initiatives and the implementation of cost-containment initiatives. Results The cost data pertaining to 27 patients were reviewed. The 2 most expensive cost activities during the index hospitalization were the total operating room (OR) and total bed-assignment costs. Together, these activities represented more than 60% of the cost of hospitalization. Although value-improvement initiatives contributed to the reduction of variation in the total cost of hospitalization, specific cost activities remained relatively variable, namely the following: 1) OR charged supplies, 2) postoperative imaging, and 3) use of intraoperative neuromonitoring. These activities, however, each contributed to less than 10% of the cost of hospitalization. Bed assignment was the fourth most variable cost activity. Cost related to readmission/reoperation represented less than 5% of the total cost of the surgical episode of care. Conclusions After completing a detailed assessment of costs incurred throughout the management of patients undergoing pituitary surgery, high-yield opportunities for cost containment should be identified among the most expensive activities and/or those with the highest variation. Strategies for safely reducing the use of the targeted resources, and related costs incurred, should be developed by the multidisciplinary team providing care for this patient population.


2010 ◽  
Vol 143 (2_suppl) ◽  
pp. P278-P278
Author(s):  
Daniel Flis ◽  
Carl Heilman ◽  
Elie Rebeiz

2007 ◽  
Vol 23 (3) ◽  
pp. 1-8 ◽  
Author(s):  
Amir R. Dehdashti ◽  
Fred Gentili

Object Transsphenoidal pituitary surgery is the primary therapy for Cushing disease because of its potential to produce lasting remission without the need for long-term drug or hormone replacement therapy. The authors evaluated the current role of pure endoscopic endonasal pituitary surgery in the treatment of Cushing disease. Methods Twenty-five patients underwent pure endoscopic surgery for confirmed Cushing disease. Thirteen patients had microadenomas and seven had macroadenomas; magnetic resonance images obtained in five patients were only suspicious or nondiagnostic, and thus they underwent inferior petrosal sinus sampling. Two patients had evidence of cavernous sinus involvement. Final histological results were consistent with adrenocorticotropin hormone (ACTH)–secreting adenoma in 20 patients. Results Twenty patients (80%) had clinical remission and laboratory confirmation of hypocortisolemia (serum cortisol < 100 nmol/L requiring substitution therapy), suppression to low-dose dexamethasone, and normal 24-hour urinary free cortisol. The median follow-up period was 17 months (range 3–32 months). There was no recurrence at the time of the last follow-up. Three patients presented with new anterior pituitary deficiency, but no one had permanent diabetes insipidus. In one patient a cerebrospinal fluid leak developed but later resolved following lumbar drainage. Treatment failure was attributable to involvement of the cavernous sinus in two patients, incomplete tumor removal in one, negative exploration in one, and nodular corticotroph hyperplasia of the pituitary gland in one. Conclusions Early results indicated that endoscopic endonasal surgery is a safe and effective treatment for ACTH-producing adenomas. The rate of remission in this study is comparable to those in previous series, and the rate of major postoperative complications is extremely low. Further studies with a larger number of patients and longer follow-ups are required to determine whether this more minimally invasive pure endoscopic approach should become the standard of care for the surgical treatment of Cushing disease.


2019 ◽  
Vol 23 (4) ◽  
Author(s):  
ZUBAIR AHMED KHAN ◽  
HABIB SULTAN ◽  
MUHAMMAD WAQAS ◽  
SARFRAZ KHAN ◽  
TOQEER AHMED ◽  
...  

Objective: To evaluate the frequency of improved visual acuity after Endoscopic Endonasal Transsphenoidal excision of pituitary gland tumor.Study Design: Descriptive case series.Materials and Methods: In our study, Pre-operative visual acuity was noted by using the Snellen’s chart. Then patients underwent pituitary gland excision though Endoscopic Endonasal Transsphenoidal approach under general anesthesia. After surgery, patients were shifted in postsurgical wards and then will be discharged from there and were examinedfor 3 months in OPD. Snellen’s chart was used to evaluate patents for visual acuity after 3 months by an experienced ophthalmologist having at least 4 years residency experience If visual acuity increased ≥ 1 line, then improved visual acuity was labeled.Results: Improved visual acuity after pituitary gland tumor excision was seen in 59(89.39%) patients. Age and gender of patients did not show any statistically significant association for improved visual acuity.Conclusions: Results of this study showed that pituitary gland tumor excision through Endoscopic Endonasal Transsphenoidal approach is effective in terms of visual acuity improvement. Our main objectives in pituitary surgery are protection and reinstatement of vision and this surgical approach give maximum cover to vision restoration.


2020 ◽  
Author(s):  
Joseph Domino ◽  
Domenico Gattozzi ◽  
Megan Jack ◽  
Charoo Iyer ◽  
Nick Harn ◽  
...  

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