The Nature of Small-Airway Obstruction in Chronic Obstructive Pulmonary Disease

2004 ◽  
Vol 351 (13) ◽  
pp. 1367-1367 ◽  
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Airway Obstruction ◽  
Pulmonary Disease ◽  
Small Airway ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Small Airway Obstruction

The Nature of Small-Airway Obstruction in Chronic Obstructive Pulmonary Disease

2004 ◽  
Vol 350 (26) ◽  
pp. 2645-2653 ◽  
Author(s):  
James C. Hogg ◽  
Fanny Chu ◽  
Soraya Utokaparch ◽  
Ryan Woods ◽  
W. Mark Elliott ◽  
...  
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Airway Obstruction ◽  
Pulmonary Disease ◽  
Small Airway ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Small Airway Obstruction

scholarly journals Small-Airway Obstruction and Emphysema in Chronic Obstructive Pulmonary Disease

2011 ◽  
Vol 365 (17) ◽  
pp. 1567-1575 ◽  
Author(s):  
John E. McDonough ◽  
Ren Yuan ◽  
Masaru Suzuki ◽  
Nazgol Seyednejad ◽  
W. Mark Elliott ◽  
...  
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Airway Obstruction ◽  
Pulmonary Disease ◽  
Small Airway ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Small Airway Obstruction

Sequelae of Childhood Respiratory Disease

1981 ◽  
Vol 2 (7) ◽  
pp. 196-212
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Air Pollution ◽  
Pulmonary Function ◽  
Airway Obstruction ◽  
Pulmonary Disease ◽  
Respiratory Disease ◽  
Chronic Obstructive ◽  
Elastic Recoil ◽  
Obstructive Pulmonary Disease ◽  
Small Airway Obstruction

Gurwitz and associates studied 17 children a decade after acute hydrocarbon pneumonitis at mean age 18 months. Eighty-two percent had pulmonary function abnormalities usually on the basis of either small airway obstruction and/or loss of elastic recoil. None of the children smoked but the pathophysiologic changes seen were similar to those of smokers. These children may be especially susceptible to the additional insults of smoking and air pollution. Comment: The implications of these studies are profound. Childhood respiratory insults may be much more significant than previously believed. Subsequent additional insults such as smoking may tip the balance toward chronic obstructive pulmonary disease.

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