Consolidating HIV testing in a public health laboratory for efficient and sustainable early infant diagnosis (EID) in Uganda

2015 ◽  
Vol 36 (2) ◽  
pp. 153-169 ◽  
Author(s):  
Charles Kiyaga ◽  
Hakim Sendagire ◽  
Eleanor Joseph ◽  
Jeff Grosz ◽  
Ian McConnell ◽  
...  
Keyword(s):  
Public Health ◽  
Hiv Testing ◽  
Public Health Laboratory ◽  
Early Infant Diagnosis ◽  
Early Infant

scholarly journals Associations of Sociodemographic and Clinical Factors with Late Presentation for Early Infant HIV Diagnosis (EID) Services in Kenya

2021 ◽  
Vol 10 (2) ◽  
pp. 210-220
Author(s):  
Agnes Langat ◽  
Tegan Callahan ◽  
Isabella Yonga ◽  
Boniface Ochanda ◽  
Anthony Waruru ◽  
...  
Keyword(s):  
Global Health ◽  
Hiv Testing ◽  
Late Presentation ◽  
Health Facilities ◽  
Inpatient Setting ◽  
Sociodemographic Characteristics ◽  
Early Infant Diagnosis ◽  
Hiv Diagnosis ◽  
Positive Polymerase Chain Reaction ◽  
Early Infant

Background: Understanding the missed opportunities in early infant HIV testing within the PMTCT program is essential to address any gaps. The study set out to describe the clinical and sociodemographic characteristics of the infants presenting late for early infant diagnosis in Kenya. Methods: We abstracted routinely collected clinical and sociodemographic characteristics, in a cross-sectional study, on all HIV-infected infants with a positive polymerase chain reaction (PCR) test from 1,346 President’s Emergency Plan for AIDS Relief (PEPFAR) supported health facilities for the period October 2016 to September 2018. We used multivariate logistic regression to examine the association of sociodemographic and clinical characteristics with late (>2 months after birth) presentation for infant HIV testing. Results: Of the 4,011 HIV-infected infants identified, the median infant age at HIV diagnosis was 3 months [interquartile range (IQR), 1-16 months], and two-thirds [2,669 (66.5%)] presented late for infant HIV testing. Factors that were associated with late presentation for infant testing were: maternal ANC non-attendance, adjusted odds ratio (aOR) 1.41 (95% confidence interval (CI) 1.18 -1.69); new maternal HIV diagnosis, aOR 1.45, (95%CI 1.24 -1.7); and lack of maternal antiretroviral therapy(ART), aOR 1.94, (95% CI 1.64 - 2.30). There was a high likelihood of identifying HIV-infected infants among infants who presented for medical services in the outpatient setting (aOR 18.9; 95% CI 10.2 - 34.9) and inpatient setting (aOR 12.2; 95% CI 6.23-23.9) compared to the infants who presented late in maternity. Conclusion and Global Health Implications: Gaps in early infant HIV testing suggest the need to increase maternal pre-pregnancy HIV diagnosis, timely antenatal care, early infant diagnosis services, early identification of mothers who seroconvert during pregnancy or breastfeeding and improved HIV screening in outpatient and inpatient settings. Early referral from the community and access to health facilities should be strengthened by the implementation of national PMTCT guidelines.   Copyright © 2021 Langat et al. Published by Global Health and Education Projects, Inc. This is an open-access article distributed under the terms of the Creative Commons Attribution License CC BY 4.0.

scholarly journals Universal HIV Screening at Postnatal Points of Care: Which Public Health Approach for Early Infant Diagnosis in Côte d'Ivoire?

PLoS ONE ◽  
2013 ◽  
Vol 8 (8) ◽  
pp. e67996 ◽  
Author(s):  
Camille Ndondoki ◽  
Hermann Brou ◽  
Marguerite Timite-Konan ◽  
Maxime Oga ◽  
Clarisse Amani-Bosse ◽  
...  
Keyword(s):  
Public Health ◽  
Cote D'ivoire ◽  
Côte D’Ivoire ◽  
Public Health Approach ◽  
Hiv Screening ◽  
Early Infant Diagnosis ◽  
Cote D’Ivoire ◽  
Early Infant ◽  
Côte D'ivoire

scholarly journals Point-of-care HIV testing best practice for early infant diagnosis: an implementation study

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Elizabeth Spooner ◽  
Kerusha Govender ◽  
Tarylee Reddy ◽  
Gita Ramjee ◽  
Noxolo Mbadi ◽  
...  
Keyword(s):  
Hiv Testing ◽  
Best Practice ◽  
Point Of Care ◽  
Implementation Study ◽  
Early Infant Diagnosis ◽  
Early Infant

Universal HIV testing of infants at immunization clinics: an acceptable and feasible approach for early infant diagnosis in high HIV prevalence settings

AIDS ◽  
2009 ◽  
Vol 23 (14) ◽  
pp. 1851-1857 ◽  
Author(s):  
Nigel Rollins ◽  
Similo Mzolo ◽  
Tammy Moodley ◽  
Tonya Esterhuizen ◽  
Heidi van Rooyen
Keyword(s):  
Hiv Testing ◽  
Hiv Prevalence ◽  
Early Infant Diagnosis ◽  
Early Infant
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