The column of heavy double turret five-axis horizontal milling complex machining center is taken as the object of study. Solidworks is used to establish three-dimensional model of milling machining center column, the established modal is be imported into ANSYS Workbench for static and dynamic characteristics analysis. First, by comparing the column deformation, the stress and strain under no-load and load conditions, which is concluded that column design is too conservative and be optimized. Secondly, the modal analysis was carried out on the column, which provides a theoretical basis for the optimization of the column by getting the first six natural frequencies and mode shapes of cloud.