scholarly journals Imaging of hemoglobin oxygen saturation variations in single vesselsin vivousing photoacoustic microscopy

2007 ◽  
Vol 90 (5) ◽  
pp. 053901 ◽  
Author(s):  
Hao F. Zhang ◽  
Konstantin Maslov ◽  
Mathangi Sivaramakrishnan ◽  
Gheorghe Stoica ◽  
Lihong V. Wang
Keyword(s):  
Oxygen Saturation ◽  
Photoacoustic Microscopy ◽  
Hemoglobin Oxygen Saturation

Excess oxygen delivery during muscle contractions in spontaneously hypertensive rats

1995 ◽  
Vol 78 (1) ◽  
pp. 101-111 ◽  
Author(s):  
J. M. Lash ◽  
H. G. Bohlen
Keyword(s):  
Blood Flow ◽  
Oxygen Saturation ◽  
Oxygen Delivery ◽  
Spontaneously Hypertensive Rats ◽  
Muscle Contractions ◽  
Hypertensive Rats ◽  
Hemoglobin Oxygen Saturation ◽  
Spontaneously Hypertensive ◽  
Tissue Po2 ◽  
Wistar Kyoto

These experiments determined whether a deficit in oxygen supply relative to demand could account for the sustained decrease in tissue PO2 observed during contractions of the spinotrapezius muscle in spontaneously hypertensive rats (SHR). Relative changes in blood flow were determined from measurements of vessel diameter and red blood cell velocity. Venular hemoglobin oxygen saturation measurements were performed by using in vivo spectrophotometric techniques. The relative dilation [times control (xCT)] of arteriolar vessels during contractions was as large or greater in SHR than in normotensive rats (Wistar-Kyoto), as were the increases in blood flow (2 Hz, 3.50 +/- 0.69 vs. 3.00 +/- 1.05 xCT; 4 Hz, 10.20 +/- 3.06 vs. 9.00 +/- 1.48 xCT; 8 Hz, 16.40 +/- 3.95 vs. 10.70 +/- 2.48 xCT). Venular hemoglobin oxygen saturation was lower in the resting muscle of SHR than of Wistar-Kyoto rats (31.0 +/= 3.0 vs. 43.0 +/- 1.9%) but was higher in SHR after 4- and 8-Hz contractions (4 Hz, 52.0 +/- 4.8 vs. 43.0 +/- 3.6%; 8 Hz, 51.0 +/- 4.6 vs. 41.0 +/- 3.6%). Therefore, an excess in oxygen delivery occurs relative to oxygen use during muscle contractions in SHR. The previous and current results can be reconciled by considering the possibility that oxygen exchange is limited in SHR by a decrease in anatomic or perfused capillary density, arteriovenular shunting of blood, or decreased transit time of red blood cells through exchange vessels.

scholarly journals Surgical component of lateral and central breast cancer treatment

2021 ◽  
Vol 102 (4) ◽  
pp. 479-485
Author(s):  
Z M Abdurakhmanova ◽  
M R Ramazanov ◽  
E I Sigal
Keyword(s):  
Breast Cancer ◽  
Lymph Nodes ◽  
Oxygen Saturation ◽  
Cancer Treatment ◽  
Comparison Group ◽  
Breast Cancer Treatment ◽  
Main Group ◽  
Regional Lymph Nodes ◽  
Hemoglobin Oxygen Saturation ◽  
Arterial Blood

Aim. To improve the results of the surgical component in the treatment of a nodular form of breast cancer with lateral and central localization by analyzing hemoglobin oxygen saturation of arterial blood in the foci of breast cancer, regional lymph nodes and resection line of the breast. Methods. The study involved 175 patients with a nodular form of breast cancer with lateral and central localization (T23N12M0), including 86 in the main group and 89 in the comparison group. In the main group, hemoglobin oxygen saturation in arterial blood of the foci of breast cancer, parenchyma, pectoral muscles and regional lymph nodes was examined for spread of cancer during surgery for nodular breast cancer by using a device developed by us (patent RU 2581266). This examination was not performed in the comparison group. Histopathological examination of resection specimens revealed confirmation of the main foci of breast cancer and the presence of metastases in the regional lymph nodes and pectoral muscles of the breast. Statistical analysis of the data was performed by using the Statistica 10 software. The arithmetic mean, the standard error of the mean and the standard deviation were calculated for the quantitative indicators. Results. In the main group, 86 patients had no recurrence and metastases in the follow-up, while in the comparison group, cancer recurrence was identified in 89 patients and metastases was found during cytological and histological studies in 9 patients. Conclusion. Determination of hemoglobin oxygen saturation of arterial blood during surgery in the subclavian, axillary and subscapular lymph nodes as well as in the pectoralis major and minor muscles allows clarifying the distribution of breast cancer, specifying the scope of the operation and improving the results of the surgical component of breast cancer treatment (T23N12M0).

Repeatability and accuracy of fingertip pulse oximeters for measurement of hemoglobin oxygen saturation in arterial blood and pulse rate in anesthetized dogs breathing 100% oxygen

2021 ◽  
Vol 82 (4) ◽  
pp. 268-273
Author(s):  
Tamas D. Ambrisko ◽  
Stephanie C. Dantino ◽  
Stephanie C. J. Keating ◽  
Danielle E. Strahl-Heldreth ◽  
Adrianna M. Sage ◽  
...  
Keyword(s):  
Oxygen Saturation ◽  
Pulse Rate ◽  
Hemoglobin Oxygen Saturation ◽  
Arterial Blood ◽  
Anesthetized Dogs ◽  
Pulse Oximeters

Oxygen exchange in the microcirculation of hamster retractor muscle

1989 ◽  
Vol 256 (1) ◽  
pp. H247-H255 ◽  
Author(s):  
D. P. Swain ◽  
R. N. Pittman
Keyword(s):  
Blood Cell ◽  
Oxygen Saturation ◽  
Oxygen Tension ◽  
Red Blood Cell ◽  
Unit Length ◽  
Retractor Muscle ◽  
Tissue Oxygen ◽  
Hemoglobin Oxygen Saturation ◽  
First Order ◽  
Weighted Values

We determined percent hemoglobin oxygen saturation (SO2) in arterioles and venules of the hamster retractor muscle at rest. We found that SO2 decreased from 69.9 +/- 1.4% (SE) in large input arterioles (first order, 1A, ID = 60 +/- 3 micron) to flow-weighted values of 56.7% in small arterioles (4A, ID = 20 +/- 1 micron), 51.3% in small venules (4V, ID = 28 +/- 1 micron), and to 50.6 +/- 1.0% in large venules (1V, ID = 147 +/- 13 micron). Thus approximately two-thirds of the net decline in SO2 for this tissue occurred by diffusion of oxygen from arterioles, whereas only about one-third occurred by diffusion from capillaries. Furthermore, no net shunting of oxygen from the arterioles to the venules was detected as evidenced by the absence of any significant change in venular SO2. By determining the SO2 at upstream and downstream ends of arterioles in four consecutive branching orders (1A-4A), we found that the decrease in SO2 per unit length (delta SO2/L) increased approximately 20-fold from 1A to 4A. This increase in delta SO2/L was directly proportional to estimated luminal minus tissue oxygen tension and inversely proportional to red blood cell flow.

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