Repeatability and accuracy of fingertip pulse oximeters for measurement of hemoglobin oxygen saturation in arterial blood and pulse rate in anesthetized dogs breathing 100% oxygen

Aim. To improve the results of the surgical component in the treatment of a nodular form of breast cancer with lateral and central localization by analyzing hemoglobin oxygen saturation of arterial blood in the foci of breast cancer, regional lymph nodes and resection line of the breast. Methods. The study involved 175 patients with a nodular form of breast cancer with lateral and central localization (T23N12M0), including 86 in the main group and 89 in the comparison group. In the main group, hemoglobin oxygen saturation in arterial blood of the foci of breast cancer, parenchyma, pectoral muscles and regional lymph nodes was examined for spread of cancer during surgery for nodular breast cancer by using a device developed by us (patent RU 2581266). This examination was not performed in the comparison group. Histopathological examination of resection specimens revealed confirmation of the main foci of breast cancer and the presence of metastases in the regional lymph nodes and pectoral muscles of the breast. Statistical analysis of the data was performed by using the Statistica 10 software. The arithmetic mean, the standard error of the mean and the standard deviation were calculated for the quantitative indicators. Results. In the main group, 86 patients had no recurrence and metastases in the follow-up, while in the comparison group, cancer recurrence was identified in 89 patients and metastases was found during cytological and histological studies in 9 patients. Conclusion. Determination of hemoglobin oxygen saturation of arterial blood during surgery in the subclavian, axillary and subscapular lymph nodes as well as in the pectoralis major and minor muscles allows clarifying the distribution of breast cancer, specifying the scope of the operation and improving the results of the surgical component of breast cancer treatment (T23N12M0).

Download Full-text

Measurement of Carboxyhemoglobin and Methemoglobin by Pulse Oximetry

Anesthesiology ◽

10.1097/00000542-200611000-00008 ◽

2006 ◽

Vol 105 (5) ◽

pp. 892-897 ◽

Cited By ~ 137

Author(s):

Steven J. Barker ◽

Jeremy Curry ◽

Daniel Redford ◽

Scott Morgan

Keyword(s):

Carbon Monoxide ◽

Oxygen Saturation ◽

Pulse Oximetry ◽

Sodium Nitrite ◽

Pulse Oximeter ◽

Hemoglobin Oxygen Saturation ◽

Arterial Blood ◽

Human Volunteers ◽

Oxygenation Monitoring ◽

Intravenous Sodium

Background A new eight-wavelength pulse oximeter is designed to measure methemoglobin and carboxyhemoglobin, in addition to the usual measurements of hemoglobin oxygen saturation and pulse rate. This study examines this device's ability to measure dyshemoglobins in human volunteers in whom controlled levels of methemoglobin and carboxyhemoglobin are induced. Methods Ten volunteers breathed 500 ppm carbon monoxide until their carboxyhemoglobin levels reached 15%, and 10 different volunteers received intravenous sodium nitrite, 300 mg, to induce methemoglobin. All were instrumented with arterial cannulas and six Masimo Rad-57 (Masimo Inc., Irvine, CA) pulse oximeter sensors. Arterial blood was analyzed by three laboratory CO-oximeters, and the resulting carboxyhemoglobin and methemoglobin measurements were compared with the corresponding pulse oximeter readings. Results The Rad-57 measured carboxyhemoglobin with an uncertainty of +/-2% within the range of 0-15%, and it measured methemoglobin with an uncertainty of 0.5% within the range of 0-12%. Conclusion The Masimo Rad-57 is the first commercially available pulse oximeter that can measure methemoglobin and carboxyhemoglobin, and it therefore represents an expansion of our oxygenation monitoring capability.

Download Full-text

Some problems involved in using hemoglobin oxygen saturation in arterial blood to detect hypoxemia and hyperoxemia in newborn infants

Scandinavian Journal of Clinical and Laboratory Investigation ◽

10.1080/00365518809168188 ◽

1988 ◽

Vol 48 (sup189) ◽

pp. 45-48 ◽

Cited By ~ 3

Author(s):

P. D Wimberley ◽

N. R. Helledie ◽

B. Friis-Hansen ◽

O. Siggaard-Andersen ◽

N. Fogh-Andersen

Keyword(s):

Oxygen Saturation ◽

Newborn Infants ◽

Hemoglobin Oxygen Saturation ◽

Arterial Blood

Download Full-text

Intraoperative intestinal viability assessment in acute bowel obstruction

Kazan medical journal ◽

10.17750/kmj2015-161 ◽

2015 ◽

Vol 96 (2) ◽

pp. 161-165 ◽

Cited By ~ 1

Author(s):

M I Nesterov ◽

M R Ramazanov ◽

M M Ramazanov ◽

E A Aliev

Keyword(s):

Oxygen Saturation ◽

Bowel Obstruction ◽

Peripheral Blood ◽

Intestinal Resection ◽

Suture Line ◽

Hemoglobin Oxygen Saturation ◽

New Device ◽

Arterial Blood ◽

Blood Hemoglobin ◽

Peripheral Blood Circulation

Aim. To improve the results of surgical treatment of acute bowel obstruction by introducing a new device and a method for intraoperative assessment of intestinal viability and further choice of resection and enteroenteroanastomosis level.Methods. Our team has designed a new device for checking the arterial blood hemoglobin oxygen saturation, pulse rate, perfusion and intramural pressure in intestinal wall. A novel method for checking peripheral blood circulation was used for choosing the resection level during the surgery and for enteroenterostomy in 50 patients of the main group. Suture line viability index was also calculated using the formula proposed by M.R. Ramazanov (2008), suture line arterial blood hemoglobin oxygen saturation was also determined. Control group included 44 patients, in whom intestinal resection and enteroenterostomy for acute bowel obstruction were performed without examining the peripheral blood circulation before the device was introduced.Results.Intramural pressure in bowel obstruction area in 10 patients was significantly lower (48.4±0.6/36.3±0.6 mm Hg at arterial blood pressure of 120.2±0.8/80±0.6 mm Hg) compared to the similar parameter in 15 healthy patients (86.5±0,9/60.3±0,5 mm Hg, pConclusion. The developed device allows to adequately access the peripheral blood flow in bowel obstruction, intestinal viability index and arterial blood hemoglobin oxygen saturation might be used in bowel obstruction to specify the intestinal resection level during surgery.

Download Full-text

Simultaneous, noninvasive, in vivo, continuous monitoring of hematocrit, vascular volume, hemoglobin oxygen saturation, pulse rate and breathing rate in humans and other animal models using a single light source

Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XVI ◽

10.1117/12.2290231 ◽

2018 ◽

Cited By ~ 2

Author(s):

James Mostrom ◽

Richard Steinmann ◽

J. Chaiken ◽

Paul Dent ◽

Sai Han Tun ◽

...

Keyword(s):

Animal Models ◽

Oxygen Saturation ◽

Light Source ◽

Pulse Rate ◽

Continuous Monitoring ◽

Breathing Rate ◽

Saturation Pulse ◽

Hemoglobin Oxygen Saturation ◽

Vascular Volume

Download Full-text

Pulse Oximetry Advantages in Infants With Bronchopulmonary Dysplasia

PEDIATRICS ◽

10.1542/peds.78.5.844 ◽

1986 ◽

Vol 78 (5) ◽

pp. 844-849 ◽

Cited By ~ 1

Author(s):

Alfonso J. Solimano ◽

John A. Smyth ◽

Tejinder K. Mann ◽

Susan G. Albersheim ◽

Gillian Lockitch

Keyword(s):

Oxygen Saturation ◽

Pulse Oximetry ◽

Bronchopulmonary Dysplasia ◽

Regression Line ◽

Arterial Catheter ◽

Radiologic Diagnosis ◽

Hemoglobin Oxygen Saturation ◽

Data Points ◽

Pulse Oximeters ◽

Inspiratory Oxygen

We studied 12 infants with a clinical and radiologic diagnosis of bronchopulmonary dysplasia who were oxygen dependent and older than 30 days. Simultaneous readings of hemoglobin oxygen saturation (Sao2) determined by two pulse oximeters (Nellcor 100, BTI Biox III) and transcutaneous (tc) Po2 (Sensor Medics, Transend) were correlated with Sao2 (Radiometer, OSM 2 Hemoximeter) and Pao2 (Corning 178) measured on blood from an indwelling arterial catheter. For each infant, the fractional inspiratory oxygen (Fio2) was adjusted to obtain three to five sets of data in the range of 70% to 95% Sao2. Fifty-three data points were generated and pooled for analysis. The slope of the regression line generated for the Nellcor 100 was .86; for the BTI Biox III, it was .91; and for the Sensor Medics Transend, it was .55, resulting in average errors of +2.5%, +1.0%, and –29%, respectively, when comparing corresponding transcutaneous and arterial values. When Sao2 was equal to or less than 95%, no infants were hyperoxic. These data confirm reports by others that tcPO2 values do not accurately represent Pao2 values in older infants with bronchopulmonary dysplasia. Pulse oximeters do not require user calibration, and their sensor is unheated so they will not cause skin burns. We conclude that pulse oximetry offers major advantages over tcPo2 measurements in the management of infants with bronchopulmonary dysplasia.

Download Full-text