Left ventricular remodeling, mechanics, and tissue characterization in congenital aortic stenosis

2003 ◽  
Vol 16 (3) ◽  
pp. 214-220 ◽  
Author(s):  
Giuseppe Pacileo ◽  
Paolo Calabrò ◽  
Giuseppe Limongelli ◽  
Maria Giovanna Russo ◽  
Carlo Pisacane ◽  
...  
Keyword(s):  
Aortic Stenosis ◽  
Tissue Characterization ◽  
Ventricular Remodeling ◽  
Left Ventricular Remodeling ◽  
Left Ventricular ◽  
Congenital Aortic Stenosis

scholarly journals Aortic stenosis with abnormal eccentric left ventricular remodeling secondary to hypothyroidism in a Bourdeaux Mastiff

2017 ◽  
Vol 47 (9) ◽  
Author(s):  
Guilherme Augusto Minozzo ◽  
Simone Tostes de Oliveira Stedile ◽  
Marlos Gonçalves Sousa
Keyword(s):  
Left Ventricular Hypertrophy ◽  
Aortic Stenosis ◽  
Ventricular Hypertrophy ◽  
Ventricular Remodeling ◽  
Left Ventricular Remodeling ◽  
Skin Lesions ◽  
Left Ventricular ◽  
The Body ◽  
Congenital Aortic Stenosis ◽  
Eccentric Hypertrophy

ABSTRACT: This paper describes a case of congenital aortic stenosis with eccentric left ventricular hypertrophy associated with hypothyroidism in a 1-year-old Bourdeaux Mastiff dog. The dog had ascites, apathy, alopecic and erythematous skin lesions in different parts of the body. A two-dimensional echocardiogram revealed aortic valve stenosis, with poststenotic dilation in the ascending aorta. The same exam showed eccentric hypertrophy and dilation of the left ventricle during systole and diastole. Aortic stenosis usually results in concentric left ventricular hypertrophy instead of eccentric hypertrophy; and therefore, this finding was very unusual. Hypothyroidism, which is uncommon in young dogs, may be incriminated as the cause of ventricular dilation, making this report even more interesting. Because hypothyroidism would only result in dilatation, the eccentric hypertrophy was attributed to pressure overload caused by aortic stenosis. Thus, cardiac alterations of this case represent a paradoxical association of both diseases.

scholarly journals Epicardial fat amount is associated with the magnitude of left ventricular remodeling in aortic stenosis

2018 ◽  
Vol 35 (2) ◽  
pp. 267-273 ◽  
Author(s):  
Augustin Coisne ◽  
Sandro Ninni ◽  
Staniel Ortmans ◽  
Laurent Davin ◽  
Kevin Kasprzak ◽  
...  
Keyword(s):  
Aortic Stenosis ◽  
Ventricular Remodeling ◽  
Left Ventricular Remodeling ◽  
Left Ventricular ◽  
Epicardial Fat

scholarly journals Evaluation of Aortic Blood Flow and Wall Shear Stress in Aortic Stenosis and Its Association With Left Ventricular Remodeling

2016 ◽  
Vol 9 (3) ◽  
Author(s):  
Florian von Knobelsdorff-Brenkenhoff ◽  
Achudhan Karunaharamoorthy ◽  
Ralf Felix Trauzeddel ◽  
Alex J. Barker ◽  
Edyta Blaszczyk ◽  
...  
Keyword(s):  
Blood Flow ◽  
Shear Stress ◽  
Wall Shear Stress ◽  
Aortic Stenosis ◽  
Ventricular Remodeling ◽  
Left Ventricular Remodeling ◽  
Left Ventricular ◽  
Aortic Blood Flow ◽  
Aortic Blood ◽  
Wall Shear

ROLE OF WINGLESS-REGULATORY MOLECULES DICKKOPF-RELATED PROTEIN 1 AND PODOCAN ON LEFT VENTRICULAR REMODELING IN PATIENTS WITH AORTIC STENOSIS

2019 ◽  
Vol 73 (9) ◽  
pp. 958
Author(s):  
Kanjit Leungsuwan ◽  
Saeeda Fatima ◽  
Abdullah Shahid ◽  
Jennifer Victory ◽  
Harish Raj Seetha Rammohan ◽  
...  
Keyword(s):  
Aortic Stenosis ◽  
Ventricular Remodeling ◽  
Left Ventricular Remodeling ◽  
Left Ventricular ◽  
Related Protein

scholarly journals Coronary Microcirculation in Aortic Stenosis: Pathophysiology, Invasive Assessment, and Future Directions

2020 ◽  
Vol 2020 ◽  
pp. 1-13
Author(s):  
Jo M. Zelis ◽  
Pim A. L. Tonino ◽  
Nico H. J. Pijls ◽  
Bernard De Bruyne ◽  
Richard L. Kirkeeide ◽  
...  
Keyword(s):  
Aortic Stenosis ◽  
Ventricular Remodeling ◽  
Left Ventricular Remodeling ◽  
Myocardial Dysfunction ◽  
Clinical Care ◽  
Microvascular Dysfunction ◽  
Left Ventricular ◽  
Link Type ◽  
Microcirculatory Function ◽  
Epicardial Stenosis

With the increasing prevalence of aortic stenosis (AS) due to a growing elderly population, a proper understanding of its physiology is paramount to guide therapy and define severity. A better understanding of the microvasculature in AS could improve clinical care by predicting left ventricular remodeling or anticipate the interplay between epicardial stenosis and myocardial dysfunction. In this review, we combine five decades of literature regarding microvascular, coronary, and aortic valve physiology with emerging insights from newly developed invasive tools for quantifying microcirculatory function. Furthermore, we describe the coupling between microcirculation and epicardial stenosis, which is currently under investigation in several randomized trials enrolling subjects with concomitant AS and coronary disease. To clarify the physiology explained previously, we present two instructive cases with invasive pressure measurements quantifying coexisting valve and coronary stenoses. Finally, we pose open clinical and research questions whose answers would further expand our knowledge of microvascular dysfunction in AS. These trials were registered with NCT03042104, NCT03094143, and NCT02436655.

Effect of Candesartan Treatment on Left Ventricular Remodeling After Aortic Valve Replacement for Aortic Stenosis

2010 ◽  
Vol 106 (5) ◽  
pp. 713-719 ◽  
Author(s):  
Jordi S. Dahl ◽  
Lars Videbaek ◽  
Mikael K. Poulsen ◽  
Patricia A. Pellikka ◽  
Karsten Veien ◽  
...  
Keyword(s):  
Aortic Valve ◽  
Aortic Stenosis ◽  
Aortic Valve Replacement ◽  
Valve Replacement ◽  
Ventricular Remodeling ◽  
Left Ventricular Remodeling ◽  
Left Ventricular
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