scholarly journals Genetics of Resistance to Tetraethyllead

1979 ◽  
Vol 32 (1) ◽  
pp. 127 ◽  
Author(s):  
R Nassar

A Drosophila melanogaster population was exposed for 25 generations to 60 pg tetraethyllead per gram of medium. Selection over this period resulted in an increase in fecundity, hatchability and larva-to-adult viability. Chromosome assay showed that response in these traits was generally under additive genetic control in conformity with existing results in the literature on the genetics of resistance to acute environmental stress in D. melanogaster.

1985 ◽  
Vol 20 (3-4) ◽  
pp. 171-177 ◽  
Author(s):  
Malcolm B. Baird ◽  
Joseph Liszczynskyj

1971 ◽  
Vol 62 (6) ◽  
pp. 345-348 ◽  
Author(s):  
THOMAS J. MIZIANTY ◽  
STEVEN T. CASE

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Fei Zhang ◽  
Jinfeng Wu ◽  
Nir Sade ◽  
Si Wu ◽  
Aiman Egbaria ◽  
...  

Abstract Background Drought is a major environmental disaster that causes crop yield loss worldwide. Metabolites are involved in various environmental stress responses of plants. However, the genetic control of metabolomes underlying crop environmental stress adaptation remains elusive. Results Here, we perform non-targeted metabolic profiling of leaves for 385 maize natural inbred lines grown under well-watered as well as drought-stressed conditions. A total of 3890 metabolites are identified and 1035 of these are differentially produced between well-watered and drought-stressed conditions, representing effective indicators of maize drought response and tolerance. Genetic dissections reveal the associations between these metabolites and thousands of single-nucleotide polymorphisms (SNPs), which represented 3415 metabolite quantitative trait loci (mQTLs) and 2589 candidate genes. 78.6% of mQTLs (2684/3415) are novel drought-responsive QTLs. The regulatory variants that control the expression of the candidate genes are revealed by expression QTL (eQTL) analysis of the transcriptomes of leaves from 197 maize natural inbred lines. Integrated metabolic and transcriptomic assays identify dozens of environment-specific hub genes and their gene-metabolite regulatory networks. Comprehensive genetic and molecular studies reveal the roles and mechanisms of two hub genes, Bx12 and ZmGLK44, in regulating maize metabolite biosynthesis and drought tolerance. Conclusion Our studies reveal the first population-level metabolomes in crop drought response and uncover the natural variations and genetic control of these metabolomes underlying crop drought adaptation, demonstrating that multi-omics is a powerful strategy to dissect the genetic mechanisms of crop complex traits.


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