Phosphorylation of eukaryotic initiation factor-2 promotes the extracellular survival of obligate intracellular parasite Toxoplasma gondii

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.1007610107 ◽

2010 ◽

Vol 107 (40) ◽

pp. 17200-17205 ◽

Author(s):

B. R. Joyce ◽

S. F. Queener ◽

R. C. Wek ◽

W. J. Sullivan

Keyword(s):

Toxoplasma Gondii ◽

Initiation Factor ◽

Eukaryotic Initiation Factor ◽

Intracellular Parasite ◽

Obligate Intracellular ◽

Obligate Intracellular Parasite ◽

Eukaryotic Initiation Factor 2 ◽

Initiation Factor 2

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Isolation of eukaryotic initiation factor 2 from yeast Saccharomyces cerevisiae.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)69920-5 ◽

1981 ◽

Vol 256 (3) ◽

pp. 1063-1066

Author(s):

R.A. Baan ◽

P.B. Keller ◽

A.E. Dahlberg

Keyword(s):

Saccharomyces Cerevisiae ◽

Initiation Factor ◽

Eukaryotic Initiation Factor ◽

Yeast Saccharomyces Cerevisiae ◽

Eukaryotic Initiation Factor 2 ◽

Initiation Factor 2

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Evidence that the primary effect of phosphorylation of eukaryotic initiation factor 2(alpha) in rabbit reticulocyte lysate is inhibition of the release of eukaryotic initiation factor-2.GDP from 60 S ribosomal subunits.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)39391-2 ◽

1985 ◽

Vol 260 (16) ◽

pp. 9491-9500 ◽

Author(s):

M Gross ◽

R Redman ◽

D A Kaplansky

Keyword(s):

Initiation Factor ◽

Primary Effect ◽

Rabbit Reticulocyte Lysate ◽

Eukaryotic Initiation Factor ◽

Ribosomal Subunits ◽

Eukaryotic Initiation Factor 2 ◽

Initiation Factor 2 ◽

Reticulocyte Lysate

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Characterization of eukaryotic initiation factor 2 containing two polypeptide chains of Mr = 48,000 and 38,000.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)69556-6 ◽

1981 ◽

Vol 256 (8) ◽

pp. 3988-3994 ◽

Author(s):

A. Chaudhuri ◽

E.A. Stringer ◽

D. Valenzuela ◽

U. Maitra

Keyword(s):

Initiation Factor ◽

Eukaryotic Initiation Factor ◽

Eukaryotic Initiation Factor 2 ◽

Initiation Factor 2 ◽

Polypeptide Chains

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Characteristics of eukaryotic initiation factor 2 and its subunits.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)86161-6 ◽

1980 ◽

Vol 255 (3) ◽

pp. 1189-1193 ◽

Author(s):

M.A. Lloyd ◽

J.C. Osborne ◽

B. Safer ◽

G.M. Powell ◽

W.C. Merrick

Keyword(s):

Initiation Factor ◽

Eukaryotic Initiation Factor ◽

Eukaryotic Initiation Factor 2 ◽

Initiation Factor 2

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Nonidentity of the 48,000-dalton protein of mRNA-protein particles and the beta subunit of eukaryotic initiation factor 2.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)86852-7 ◽

1979 ◽

Vol 254 (17) ◽

pp. 8087-8090

Author(s):

A. Barrieux ◽

M.G. Rosenfeld

Keyword(s):

Beta Subunit ◽

Initiation Factor ◽

Eukaryotic Initiation Factor ◽

Eukaryotic Initiation Factor 2 ◽

Initiation Factor 2 ◽

Protein Particles

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Phosphorylation of Plant Eukaryotic Initiation Factor-2 by the Plant-encoded Double-stranded RNA-dependent Protein Kinase, pPKR, and Inhibition of Protein Synthesisin Vitro

Journal of Biological Chemistry ◽

10.1074/jbc.271.8.4539 ◽

1996 ◽

Vol 271 (8) ◽

pp. 4539-4544 ◽

Author(s):

Jeffrey O. Langland ◽

Lisa A. Langland ◽

Karen S. Browning ◽

Don A. Roth

Keyword(s):

Protein Kinase ◽

Initiation Factor ◽

Eukaryotic Initiation Factor ◽

Dependent Protein Kinase ◽

Double Stranded Rna ◽

Eukaryotic Initiation Factor 2 ◽

Initiation Factor 2 ◽

Dependent Protein

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The Interaction between Viral Messenger RNA and Eukaryotic Initiation Factor 2, a Protein Involved in Translational Control

Viral Messenger RNA ◽

10.1007/978-1-4613-2585-7_2 ◽

1985 ◽

pp. 21-48

Author(s):

Raymond Kaempfer

Keyword(s):

Translational Control ◽

Messenger Rna ◽

Initiation Factor ◽

Eukaryotic Initiation Factor ◽

Eukaryotic Initiation Factor 2 ◽

Initiation Factor 2

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Nuclear Factor 90 Is a Substrate and Regulator of the Eukaryotic Initiation Factor 2 Kinase Double-stranded RNA-activated Protein Kinase

Journal of Biological Chemistry ◽

10.1074/jbc.m104408200 ◽

2001 ◽

Vol 276 (35) ◽

pp. 32522-32530 ◽

Author(s):

Lisa M. Parker ◽

Ivo Fierro-Monti ◽

Michael B. Mathews

Keyword(s):

Protein Kinase ◽

Initiation Factor ◽

Nuclear Factor ◽

Eukaryotic Initiation Factor ◽

Double Stranded Rna ◽

Eukaryotic Initiation Factor 2 ◽

Initiation Factor 2

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The N-terminal lysine residue-rich domain II and the 340–430 amino acid segment of eukaryotic initiation factor 2-associated glycoprotein p67 are the binding sites for the γ-subunit of eIF2

Experimental Cell Research ◽

10.1016/j.yexcr.2006.03.034 ◽

2006 ◽

Vol 312 (16) ◽

pp. 3184-3203 ◽

Author(s):

Arnab Ghosh ◽

Rekha Datta ◽

Avijit Majumdar ◽

Mahasweta Bhattacharya ◽

Bansidhar Datta

Keyword(s):

Binding Sites ◽

Lysine Residue ◽

Initiation Factor ◽

Eukaryotic Initiation Factor ◽

Rich Domain ◽

Eukaryotic Initiation Factor 2 ◽

Initiation Factor 2 ◽

Amino Acid Segment

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[20] RNA-affinity chromatography: Its use in purification of eukaryotic initiation factor 2

Methods in Enzymology - Nucleic Acids and Protein Synthesis Part H ◽

10.1016/s0076-6879(79)60022-8 ◽

1979 ◽

pp. 247-255 ◽

Author(s):

Raymond Kaempfer

Keyword(s):

Affinity Chromatography ◽

Initiation Factor ◽

Eukaryotic Initiation Factor ◽

Eukaryotic Initiation Factor 2 ◽

Initiation Factor 2

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