scholarly journals Phenylalanyl-tRNA synthetase from baker's yeast: role of 3'-terminal adenosine of tRNA-Phe in enzyme-substrate interaction studied with 3'-modified tRNA-Phe species.

1975 ◽  
Vol 72 (4) ◽  
pp. 1378-1382 ◽  
Author(s):  
F. Von Der Haar ◽  
E. Gaertner
1977 ◽  
Vol 76 (1) ◽  
pp. 263-267 ◽  
Author(s):  
Friedrich HAAR ◽  
Friedrich CRAMER ◽  
Fritz ECKSTEIN ◽  
Kurt-Wilhelm STAHL

Biochimie ◽  
1983 ◽  
Vol 65 (7) ◽  
pp. 379-388 ◽  
Author(s):  
N HOUNWANOU ◽  
Y BOULANGER ◽  
J REINBOLT

2013 ◽  
Vol 2013 ◽  
pp. 1-9 ◽  
Author(s):  
V. Franssens ◽  
T. Bynens ◽  
J. Van den Brande ◽  
K. Vandermeeren ◽  
M. Verduyckt ◽  
...  

Over the past decade, the baker’s yeastSaccharomyces cerevisiaehas proven to be a useful model system to investigate fundamental questions concerning the pathogenic role of human proteins in neurodegenerative diseases such as Parkinson’s disease (PD). These so-called humanized yeast models for PD initially focused onα-synuclein, which plays a key role in the etiology of PD. Upon expression of this human protein in the baker’s yeastSaccharomyces cerevisiae, the events leading to aggregation and the molecular mechanisms that result in cellular toxicity are faithfully reproduced. More recently, a similar model to study the presumed pathobiology of theα-synuclein interaction partner synphilin-1 has been established. In this review we will discuss recent advances using these humanized yeast models, pointing to new roles for cell wall integrity signaling, Ca2+homeostasis, mitophagy, and the cytoskeleton.


1980 ◽  
Vol 616 (1) ◽  
pp. 82-88 ◽  
Author(s):  
Masataka Yoshino ◽  
Keiko Murakami

FEBS Letters ◽  
1989 ◽  
Vol 242 (2) ◽  
pp. 351-356 ◽  
Author(s):  
F. Fasiolo ◽  
A. Sanni ◽  
S. Potier ◽  
J.P. Ebel ◽  
Y. Boulanger

Sign in / Sign up

Export Citation Format

Share Document