scholarly journals Separation of the arterial wall from blood contact using hydrogel barriers reduces intimal thickening after balloon injury in the rat: The roles of medial and luminal factors in arterial healing

1996 ◽  
Vol 93 (23) ◽  
pp. 13188-13193 ◽  
Author(s):  
J. L. West ◽  
J. A. Hubbell
2008 ◽  
Vol 22 (4) ◽  
pp. 506-510 ◽  
Author(s):  
Fenye Liu ◽  
Jidong Zhang ◽  
Shudong Yu ◽  
Rong Wang ◽  
Bo Wang ◽  
...  

1979 ◽  
Author(s):  
A.K. Horsch ◽  
P. Klaiber ◽  
K. Dennig ◽  
W. Hofmann

Early atherosclerotic lesions in rat aortas were produced by synergy of cholesterol feeding (4 g cholesterol and 2 g cholate in Ioo g pellets) and immunological injury (5 repeated immunizations with 1 mg of horse-radishperoxidase). Cholesterol feeding and immunization was started the same day and resulted after 6 weeks in endothelial injury, intimal thickening and edema, in proliferation of intimal smooth muscle cells and in deposition of lipids and immune complexes in the arterial wall.100 rats were studied and no lesions were detected in the control group, minimal changes were seen in the animals receiving cholesterol or immunization alone, but lesions were constantly present in the group receiving both regimens. One group of cholesterol fed and immunized rats was given sulfinpyrazone from the beginning of the experiment (160 mg/kg/d) over the 6 weeks and a significant reduction in lesion formation was observed compared to the non treated animals. These results suggest a protection of the arterial wall by sulfinpyrazone in experimental atherosclerosis.


2020 ◽  
Vol 49 ◽  
pp. 107230
Author(s):  
Yonghong Li ◽  
Junjie Guo ◽  
Haichu Yu ◽  
Jingwei Zhou ◽  
Xianming Chu ◽  
...  

2020 ◽  
Vol 72 (1) ◽  
pp. e265
Author(s):  
Samuel Röhl ◽  
Valeriy Vavilov ◽  
Kenneth Caidahl ◽  
Ulf Hedin ◽  
Claes-Goran Ostenson ◽  
...  

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