Single Amino Acid Substitutions in α-Conotoxin PnIA Shift Selectivity for Subtypes of the Mammalian Neuronal Nicotinic Acetylcholine Receptor

Single Amino Acid ◽

Amino Acid Substitutions ◽

Amino acid residues forming the interface of a neuronal nicotinic acetylcholine receptor with κ-bungarotoxin: A study using single residue substituted peptide analogs

Biochemical and Biophysical Research Communications ◽

10.1016/0006-291x(91)90882-8 ◽

1991 ◽

Vol 176 (1) ◽

pp. 11-17 ◽

Cited By ~ 9

Author(s):

Kathryn E. McLane ◽

Xiadong Wu ◽

Bianca M. Conti-Tronconi

Keyword(s):

Amino Acid ◽

Acetylcholine Receptor ◽

Amino Acid Residues ◽

Nicotinic Acetylcholine ◽

Peptide Analogs

Single Amino Acid Substitution in α-Conotoxin TxID Reveals a Specific α3β4 Nicotinic Acetylcholine Receptor Antagonist

Journal of Medicinal Chemistry ◽

10.1021/acs.jmedchem.8b00967 ◽

2018 ◽

Vol 61 (20) ◽

pp. 9256-9265 ◽

Cited By ~ 11

Author(s):

Jinpeng Yu ◽

Xiaopeng Zhu ◽

Peta J. Harvey ◽

Quentin Kaas ◽

Dongting Zhangsun ◽

...

Keyword(s):

Amino Acid ◽

Receptor Antagonist ◽

Acetylcholine Receptor ◽

Amino Acid Substitution ◽

Single Amino Acid Substitution ◽

Single Amino Acid ◽

A single amino acid polymorphism in theDrosophila melanogasterDα1 (ALS) subunit enhances neonicotinoid efficacy at Dα1-chicken β2 hybrid nicotinic acetylcholine receptor expressed inXenopus laevisoocytes

Bioscience Biotechnology and Biochemistry ◽

10.1080/09168451.2014.891928 ◽

2014 ◽

Vol 78 (4) ◽

pp. 543-549 ◽

Cited By ~ 3

Author(s):

Makoto Ihara ◽

Naoya Shimazu ◽

Mai Utsunomiya ◽

Miki Akamatsu ◽

David B. Sattelle ◽

...

Keyword(s):

Amino Acid ◽

Acetylcholine Receptor ◽

Single Amino Acid ◽

Amino Acid Polymorphism ◽

Nicotinic Acetylcholine ◽

Single Amino Acid Polymorphism

Structural determinants of .alpha.-bungarotoxin binding to the sequence segment 181-200 of the muscle nicotinic acetylcholine receptor .alpha. subunit: effects of cysteine/cystine modification and species-specific amino acid substitutions

Biochemistry ◽

10.1021/bi00234a013 ◽

1991 ◽

Vol 30 (20) ◽

pp. 4925-4934 ◽

Cited By ~ 35

Author(s):

Kathryn E. McLane ◽

Xiadong Wu ◽

Brenda Diethelm ◽

Bianca M. Conti-Tronconi

Keyword(s):

Amino Acid ◽

Acetylcholine Receptor ◽

Alpha Subunit ◽

Amino Acid Substitutions ◽

Structural Determinants ◽

Nicotinic Acetylcholine ◽

Specific Amino Acid ◽

Species Specific ◽

Alpha Bungarotoxin

An .alpha.-Bungarotoxin-Binding Sequence on the Torpedo Nicotinic Acetylcholine Receptor .alpha.-Subunit: Conservative Amino Acid Substitutions Reveal Side-Chain Specific Interactions

Biochemistry ◽

10.1021/bi00175a029 ◽

1994 ◽

Vol 33 (9) ◽

pp. 2576-2585 ◽

Cited By ~ 13

Author(s):

Kathryn E. McLane ◽

Xiadong Wu ◽

Bianca M. Conti-Tronconi

Keyword(s):

Amino Acid ◽

Acetylcholine Receptor ◽

Alpha Subunit ◽

Side Chain ◽

Amino Acid Substitutions ◽

Specific Interactions ◽

Nicotinic Acetylcholine ◽

Alpha Bungarotoxin ◽

Binding Sequence

Identification of polypeptides associated with a putative neuronal nicotinic acetylcholine receptor.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)33771-2 ◽

1982 ◽

Vol 257 (19) ◽

pp. 11390-11394

Author(s):

H Betz ◽

D Graham ◽

H Rehm

Keyword(s):

Acetylcholine Receptor ◽

5371188 Neuronal nicotinic acetylcholine receptor compositions

Biotechnology Advances ◽

10.1016/0734-9750(96)84630-1 ◽

1995 ◽

Vol 13 (4) ◽

pp. 716

Keyword(s):

Acetylcholine Receptor ◽

Genetic association analysis of tagging SNPs in alpha4 and beta2 subunits of neuronal nicotinic acetylcholine receptor genes (CHRNA4 and CHRNB2) with schizophrenia in the Japanese population

Journal of Neural Transmission ◽

10.1007/s00702-008-0114-8 ◽

2008 ◽

Vol 115 (10) ◽

pp. 1457-1461 ◽

Cited By ~ 8

Author(s):

Taro Kishi ◽

Masashi Ikeda ◽

Tsuyoshi Kitajima ◽

Yoshio Yamanouchi ◽

Yoko Kinoshita ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Genetic Association ◽

Association Analysis ◽

Japanese Population ◽

Genetic Association Analysis ◽

Analysis of specificity of antibodies against synthetic fragments of different neuronal nicotinic acetylcholine receptor subunits

Biochemistry (Moscow) ◽

10.1134/s0006297906070078 ◽

2006 ◽

Vol 71 (7) ◽

pp. 749-758 ◽

Cited By ~ 7

Author(s):

I. V. Shelukhina ◽

E. V. Kryukova ◽

M. V. Skok ◽

E. Yu. Lykhmus ◽

M. N. Zhmak ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Functional Properties of the Neuronal Nicotinic Acetylcholine Receptor β3 Promoter in the Developing Central Nervous System

Journal of Biological Chemistry ◽

10.1074/jbc.273.24.15131 ◽

1998 ◽

Vol 273 (24) ◽

pp. 15131-15137 ◽

Cited By ~ 11

Author(s):

Tomas Roztocil ◽

Lidia Matter-Sadzinski ◽

Marie Gomez ◽

Marc Ballivet ◽

Jean-Marc Matter

Keyword(s):

Central Nervous System ◽

Nervous System ◽

Acetylcholine Receptor ◽

Functional Properties ◽