Structure-guided Inhibitor Design for Human Acetyl-coenzyme A Carboxylase by Interspecies Active Site Conversion

Journal of Biological Chemistry ◽

10.1074/jbc.m111.275396 ◽

2011 ◽

Vol 286 (48) ◽

pp. 41510-41519 ◽

Author(s):

Francis Rajamohan ◽

Eric Marr ◽

Allan R. Reyes ◽

James A. Landro ◽

Marie D. Anderson ◽

...

Keyword(s):

Active Site ◽

Inhibitor Design ◽

Acetyl Coenzyme A ◽

Acetyl Coenzyme ◽

Acetyl Coenzyme A Carboxylase

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A Comparative Study of Drug Resistance Mechanism Associated with Active Site and Non-Active Site Mutations: I388N and D425G Mutants of Acetyl-Coenzyme-A Carboxylase

Current Computer - Aided Drug Design ◽

10.2174/157340912799218480 ◽

2012 ◽

Vol 8 (1) ◽

pp. 62-69 ◽

Author(s):

Xiao-Lei Zhu ◽

Guang-Fu Yang

Keyword(s):

Drug Resistance ◽

Comparative Study ◽

Active Site ◽

Resistance Mechanism ◽

Acetyl Coenzyme A ◽

Acetyl Coenzyme ◽

Acetyl Coenzyme A Carboxylase ◽

Active Site Mutations

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Dietary whole and cracked linseed increases the proportion of oleic and α-linolenic acids in adipose tissues and decreases stearoyl-coenzyme A desaturase, acetyl-coenzyme A carboxylase, and fatty acid synthase gene expression in the longissimus thoracis muscle of Yanbian Yellow cattle

Journal of Animal Science ◽

10.2527/jas2016.1050 ◽

2017 ◽

Vol 95 (2) ◽

pp. 718

Author(s):

X. Z. Li ◽

C. G. Yan ◽

J. Yu ◽

Q. S. Gao ◽

S. H. Choi ◽

...

Keyword(s):

Gene Expression ◽

Fatty Acid Synthase ◽

Adipose Tissues ◽

Acetyl Coenzyme A ◽

Acetyl Coenzyme ◽

Yellow Cattle ◽

Acetyl Coenzyme A Carboxylase ◽

Fatty Acid Synthase Gene

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Faculty Opinions recommendation of Novel bacterial acetyl coenzyme A carboxylase inhibitors with antibiotic efficacy in vivo.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1033853.506623 ◽

2006 ◽

Author(s):

Kim Lewis

Keyword(s):

Acetyl Coenzyme A ◽

Acetyl Coenzyme ◽

Antibiotic Efficacy ◽

Acetyl Coenzyme A Carboxylase

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Age-Related Changes in Rat Hepatic Acetyl-Coenzyme A Carboxylase

Proceedings of The Society for Experimental Biology and Medicine ◽

10.1046/j.1525-1373.2000.22515.x ◽

2000 ◽

Vol 225 (2) ◽

pp. 123-127 ◽

Author(s):

K. George Thampy ◽

Michael J. Haas ◽

Arshag D. Mooradian

Keyword(s):

Acetyl Coenzyme A ◽

Acetyl Coenzyme ◽

Age Related ◽

Acetyl Coenzyme A Carboxylase ◽

Age Related Changes

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Computational exploration and anti-mycobacterial activity of potential inhibitors of Mycobacterium tuberculosis acetyl coenzyme A carboxylase as anti-tubercular agents

SAR and QSAR in Environmental Research ◽

10.1080/1062936x.2021.1882563 ◽

2021 ◽

Vol 32 (3) ◽

pp. 191-205

Author(s):

J. Kuldeep ◽

S.K. Sharma ◽

B.N. Singh ◽

M.I. Siddiqi

Keyword(s):

Mycobacterium Tuberculosis ◽

Acetyl Coenzyme A ◽

Acetyl Coenzyme ◽

Computational Exploration ◽

Potential Inhibitors ◽

Acetyl Coenzyme A Carboxylase

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Acetyl Coenzyme A Carboxylase

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)63531-8 ◽

1969 ◽

Vol 244 (22) ◽

pp. 6254-6262 ◽

Author(s):

Philip W. Majerus ◽

Elisabeth Kilburn

Keyword(s):

Acetyl Coenzyme A ◽

Acetyl Coenzyme ◽

Acetyl Coenzyme A Carboxylase

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Acetyl coenzyme A carboxylase. Rapid purification of the chick liver enzyme and steady state kinetic analysis of the carboxylase-catalyzed reaction.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)68288-8 ◽

1982 ◽

Vol 257 (2) ◽

pp. 924-929 ◽

Author(s):

N.B. Beaty ◽

M.D. Lane

Keyword(s):

Steady State ◽

Kinetic Analysis ◽

Liver Enzyme ◽

Acetyl Coenzyme A ◽

Acetyl Coenzyme ◽

Steady State Kinetic ◽

Rapid Purification ◽

Acetyl Coenzyme A Carboxylase ◽

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Interaction of the fluorescent analogue stearoyl-(1,N6)-etheno coenzyme A with chicken liver acetyl coenzyme A carboxylase.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)85706-x ◽

1980 ◽

Vol 255 (8) ◽

pp. 3348-3351

Author(s):

K. Sreekrishna ◽

S. Gunsberg ◽

S.J. Wakil ◽

V.C. Joshi

Keyword(s):

Chicken Liver ◽

Acetyl Coenzyme A ◽

Acetyl Coenzyme ◽

Acetyl Coenzyme A Carboxylase

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Identification of the cyclic AMP and ATP binding sites of acetyl coenzyme A carboxylase by use of 5'-p-fluorosulfonylbenzoyladenosine.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)33969-3 ◽

1982 ◽

Vol 257 (17) ◽

pp. 9953-9957

Author(s):

S L Chen ◽

K H Kim

Keyword(s):

Binding Sites ◽

Atp Binding ◽

Acetyl Coenzyme A ◽

Acetyl Coenzyme ◽

Acetyl Coenzyme A Carboxylase

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Acetyl Coenzyme A Carboxylase

Journal of Biological Chemistry ◽

10.1016/s0021-9258(20)81801-8 ◽

1972 ◽

Vol 247 (24) ◽

pp. 8005-8015

Author(s):

R. Ray Fall ◽

P. Roy Vagelos

Keyword(s):

Acetyl Coenzyme A ◽

Acetyl Coenzyme ◽

Acetyl Coenzyme A Carboxylase

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