Proteinase-activated Receptor-2 Transactivation of Epidermal Growth Factor Receptor and Transforming Growth Factor-β Receptor Signaling Pathways Contributes to Renal Fibrosis

Hyunjae Chung; Rithwik Ramachandran; Morley D. Hollenberg; Daniel A. Muruve

doi:10.1074/jbc.m113.492793

Proteinase-activated Receptor-2 Transactivation of Epidermal Growth Factor Receptor and Transforming Growth Factor-β Receptor Signaling Pathways Contributes to Renal Fibrosis

Journal of Biological Chemistry ◽

10.1074/jbc.m113.492793 ◽

2013 ◽

Vol 288 (52) ◽

pp. 37319-37331 ◽

Cited By ~ 52

Author(s):

Hyunjae Chung ◽

Rithwik Ramachandran ◽

Morley D. Hollenberg ◽

Daniel A. Muruve

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Signaling Pathways ◽

Renal Fibrosis ◽

Transforming Growth Factor ◽

Growth Factor Receptor ◽

Transforming Growth Factor Β ◽

Epidermal Growth ◽

Β Receptor

Download Full-text

Ligand release-independent transactivation of epidermal growth factor receptor by transforming growth factor-β involves multiple signaling pathways

Oncogene ◽

10.1038/sj.onc.1210649 ◽

2007 ◽

Vol 27 (5) ◽

pp. 614-628 ◽

Cited By ~ 35

Author(s):

C-K Joo ◽

H-S Kim ◽

J-Y Park ◽

Y Seomun ◽

M-J Son ◽

...

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Signaling Pathways ◽

Transforming Growth Factor ◽

Growth Factor Receptor ◽

Transforming Growth Factor Β ◽

Epidermal Growth ◽

Multiple Signaling

Download Full-text

Faculty Opinions recommendation of Amphiregulin, an epidermal growth factor receptor ligand, plays an essential role in the pathogenesis of transforming growth factor-β-induced pulmonary fibrosis.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717961086.793463969 ◽

2012 ◽

Author(s):

Darryl Knight

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Pulmonary Fibrosis ◽

Essential Role ◽

Transforming Growth Factor ◽

Growth Factor Receptor ◽

Transforming Growth Factor Β ◽

Receptor Ligand ◽

Epidermal Growth

Download Full-text

Loss of EMILIN-1 Enhances Arteriolar Myogenic Tone Through TGF-β (Transforming Growth Factor-β)–Dependent Transactivation of EGFR (Epidermal Growth Factor Receptor) and Is Relevant for Hypertension in Mice and Humans

Arteriosclerosis Thrombosis and Vascular Biology ◽

10.1161/atvbaha.118.311115 ◽

2018 ◽

Vol 38 (10) ◽

pp. 2484-2497 ◽

Cited By ~ 8

Author(s):

Daniela Carnevale ◽

Nicola Facchinello ◽

Daniele Iodice ◽

Dario Bizzotto ◽

Marialuisa Perrotta ◽

...

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Transforming Growth Factor ◽

Growth Factor Receptor ◽

Transforming Growth Factor Β ◽

Myogenic Tone ◽

Epidermal Growth

Download Full-text

Transforming Growth Factor β Regulation of Epidermal Growth Factor Receptor in Ectocervical Epithelial Cells

Experimental Cell Research ◽

10.1006/excr.1995.1330 ◽

1995 ◽

Vol 220 (2) ◽

pp. 390-396 ◽

Cited By ~ 14

Author(s):

James W. Jacoeberger ◽

Nywana Sizemore ◽

George Gorodeski ◽

Ellen A. Rorke

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Epithelial Cells ◽

Transforming Growth Factor ◽

Growth Factor Receptor ◽

Transforming Growth Factor Β ◽

Epidermal Growth

Download Full-text

New mechanism of transforming growth factor-β signaling in hepatoma: Dramatic up-regulation of tumor initiating cells and epidermal growth factor receptor expression

Hepatology Research ◽

10.1111/j.1872-034x.2008.00480.x ◽

2009 ◽

Vol 39 (5) ◽

pp. 501-509 ◽

Cited By ~ 4

Author(s):

Takeshi Nishimura ◽

Toshifumi Azuma ◽

Akiko Yokoyama ◽

Hiromi Ochiai ◽

Hidetsugu Saito ◽

...

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Transforming Growth Factor ◽

Growth Factor Receptor ◽

Transforming Growth Factor Β ◽

Receptor Expression ◽

Tumor Initiating Cells ◽

Epidermal Growth

Download Full-text

Downregulation of Epidermal Growth Factor Receptor in hepatocellular carcinoma facilitates Transforming Growth Factor-β-induced epithelial to amoeboid transition

Cancer Letters ◽

10.1016/j.canlet.2019.08.011 ◽

2019 ◽

Vol 464 ◽

pp. 15-24 ◽

Cited By ~ 3

Author(s):

Judit López-Luque ◽

Esther Bertran ◽

Eva Crosas-Molist ◽

Oscar Maiques ◽

Andrea Malfettone ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Transforming Growth Factor ◽

Growth Factor Receptor ◽

Transforming Growth Factor Β ◽

Epidermal Growth

Download Full-text

Amphiregulin, an Epidermal Growth Factor Receptor Ligand, Plays an Essential Role in the Pathogenesis of Transforming Growth Factor-β-induced Pulmonary Fibrosis

Journal of Biological Chemistry ◽

10.1074/jbc.m112.356824 ◽

2012 ◽

Vol 287 (50) ◽

pp. 41991-42000 ◽

Cited By ~ 79

Author(s):

Yang Zhou ◽

Jae-Young Lee ◽

Chang-Min Lee ◽

Won-Kyung Cho ◽

Min-Jong Kang ◽

...

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Pulmonary Fibrosis ◽

Essential Role ◽

Transforming Growth Factor ◽

Growth Factor Receptor ◽

Transforming Growth Factor Β ◽

Receptor Ligand ◽

Epidermal Growth

Download Full-text

Epidermal Growth Factor Receptor and Transforming Growth Factor-β Signaling Contributes to Variation for Wing Shape inDrosophila melanogaster

Genetics ◽

10.1534/genetics.105.053868 ◽

2006 ◽

Vol 173 (3) ◽

pp. 1417-1431 ◽

Cited By ~ 67

Author(s):

Ian Dworkin ◽

Greg Gibson

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Transforming Growth Factor ◽

Growth Factor Receptor ◽

Transforming Growth Factor Β ◽

Wing Shape ◽

Epidermal Growth

Download Full-text

Angiotensin II–Induced Transactivation of Epidermal Growth Factor Receptor Regulates Fibronectin and Transforming Growth Factor-β Synthesis via Transcriptional and Posttranscriptional Mechanisms

Circulation Research ◽

10.1161/01.res.84.9.1073 ◽

1999 ◽

Vol 84 (9) ◽

pp. 1073-1084 ◽

Cited By ~ 69

Author(s):

Yasutaka Moriguchi ◽

Hiroaki Matsubara ◽

Yasukiyo Mori ◽

Satoshi Murasawa ◽

Hiroya Masaki ◽

...

Keyword(s):

Epidermal Growth Factor Receptor ◽

Angiotensin Ii ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Transforming Growth Factor ◽

Growth Factor Receptor ◽

Transforming Growth Factor Β ◽

Epidermal Growth

Download Full-text

Endothelin-1 Stimulates Cyclooxygenase-2 Expression in Ovarian Cancer Cells Through Multiple Signaling Pathways: Evidence for Involvement of Transactivation of the Epidermal Growth Factor Receptor

Journal of Cardiovascular Pharmacology ◽

10.1097/01.fjc.0000166255.12229.0d ◽

2004 ◽

Vol 44 (Supplement 1) ◽

pp. S140-S143 ◽

Cited By ~ 18

Author(s):

Francesca Spinella ◽

Laura Rosan?? ◽

Giacomo Elia ◽

Valeriana Di Castro ◽

Pier Giorgio Natali ◽

...

Keyword(s):

Ovarian Cancer ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Cancer Cells ◽

Signaling Pathways ◽

Growth Factor Receptor ◽

Ovarian Cancer Cells ◽

Epidermal Growth ◽

Multiple Signaling

Download Full-text