scholarly journals Chemically Modified DNA Aptamers Bind Interleukin-6 with High Affinity and Inhibit Signaling by Blocking Its Interaction with Interleukin-6 Receptor

2014 ◽  
Vol 289 (12) ◽  
pp. 8706-8719 ◽  
Author(s):  
Shashi Gupta ◽  
Masao Hirota ◽  
Sheela M. Waugh ◽  
Ikuo Murakami ◽  
Tomoki Suzuki ◽  
...  
Keyword(s):  
Interleukin 6 ◽  
Dna Aptamers ◽  
Chemically Modified ◽  
High Affinity ◽  
Modified Dna ◽  
Interleukin 6 Receptor

scholarly journals Pyrene-Modified DNA Aptamers with High Affinity to Wild-Type EGFR and EGFRvIII

2020 ◽  
Vol 30 (3) ◽  
pp. 175-187 ◽  
Author(s):  
Elena Zavyalova ◽  
Askar Turashev ◽  
Anastasia Novoseltseva ◽  
Valeriia Legatova ◽  
Olga Antipova ◽  
...  
Keyword(s):  
Dna Aptamers ◽  
Wild Type ◽  
High Affinity ◽  
Modified Dna

scholarly journals High affinity interleukin-6 receptor is a hexameric complex consisting of two molecules each of interleukin-6, interleukin-6 receptor, and gp-130.

1994 ◽  
Vol 269 (37) ◽  
pp. 23286-23289 ◽  
Author(s):  
L.D. Ward ◽  
G.J. Howlett ◽  
G. Discolo ◽  
K. Yasukawa ◽  
A. Hammacher ◽  
...  
Keyword(s):  
Interleukin 6 ◽  
High Affinity ◽  
Interleukin 6 Receptor

The N-Terminus of gp130 is Critical for the Formation of the High-Affinity Interleukin-6 Receptor Complex

1999 ◽  
Vol 16 (4) ◽  
pp. 265-278 ◽  
Author(s):  
Robert L. Moritz ◽  
Larry D. Ward ◽  
Guo-Fen Tu ◽  
Louis J. Fabri ◽  
Hong Ji ◽  
...  
Keyword(s):  
Interleukin 6 ◽  
Receptor Complex ◽  
High Affinity ◽  
N Terminus ◽  
Interleukin 6 Receptor

The effect of tocilizumab - an interleukin-6 receptor antagonist - on lipid levels in rheumatoid arthritis

2017 ◽  
Author(s):  
Ifigenia Kostoglou-Athanassiou ◽  
Lambros Athanassiou ◽  
Aikaterini Tzanavari ◽  
Charoula Katsavouni ◽  
Markos Kostopoulos ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Receptor Antagonist ◽  
Interleukin 6 ◽  
Lipid Levels ◽  
Interleukin 6 Receptor

A synthetic corticosteroid, dexamethasone regulates generation of soluble form of interleukin-6 receptor of human lymphocytes, in vitro

2002 ◽  
Vol 53 (3) ◽  
pp. 307-315 ◽  
Author(s):  
Anna Polgár ◽  
Márta Brózik ◽  
Sára Tóth ◽  
Marcsilla Holub ◽  
A. Falus
Keyword(s):  
Interleukin 6 ◽  
Human Lymphocytes ◽  
Soluble Form ◽  
Interleukin 6 Receptor
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