The CYP4A Isoforms Hydroxylate Epoxyeicosatrienoic Acids to Form High Affinity Peroxisome Proliferator-activated Receptor Ligands

Journal of Biological Chemistry ◽

10.1074/jbc.m201575200 ◽

2002 ◽

Vol 277 (38) ◽

pp. 35105-35112 ◽

Author(s):

L. Ashley Cowart ◽

Shouzuo Wei ◽

Mei-Hui Hsu ◽

Eric F. Johnson ◽

Murali U. Krishna ◽

...

Keyword(s):

Epoxyeicosatrienoic Acids ◽

Peroxisome Proliferator ◽

Receptor Ligands ◽

Peroxisome Proliferator Activated Receptor ◽

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Peroxisome proliferator-activated receptor ligands negatively regulate the expression of the high-affinity IgE receptor FcεRI in human basophilic KU812 cells

Biochemical and Biophysical Research Communications ◽

10.1016/s0006-291x(02)02139-3 ◽

2002 ◽

Vol 297 (2) ◽

pp. 193-201 ◽

Author(s):

Yoshinori Fujimura ◽

Hirofumi Tachibana ◽

Koji Yamada

Keyword(s):

Peroxisome Proliferator ◽

Receptor Ligands ◽

Ige Receptor ◽

Peroxisome Proliferator Activated Receptor ◽

High Affinity ◽

Ku812 Cells ◽

High Affinity Ige Receptor

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Faculty Opinions recommendation of Fatty acid transduction of nitric oxide signaling: multiple nitrated unsaturated fatty acid derivatives exist in human blood and urine and serve as endogenous peroxisome proliferator-activated receptor ligands.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1029820.347601 ◽

2005 ◽

Author(s):

John Helmann

Keyword(s):

Nitric Oxide ◽

Human Blood ◽

Unsaturated Fatty Acid ◽

Peroxisome Proliferator ◽

Receptor Ligands ◽

Peroxisome Proliferator Activated Receptor ◽

Nitric Oxide Signaling ◽

Fatty Acid Derivatives ◽

Human Blood And Urine

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Effects of Peroxisome Proliferator-Activated Receptor Ligands in Modulating Tissue Factor and Tissue Factor Pathway Inhibitor in Acutely Symptomatic Carotid Atheromas

Stroke ◽

10.1161/strokeaha.106.474791 ◽

2007 ◽

Vol 38 (5) ◽

pp. 1501-1508 ◽

Author(s):

Jonathan Golledge ◽

Simone Mangan ◽

Paula Clancy

Keyword(s):

Tissue Factor ◽

Tissue Factor Pathway Inhibitor ◽

Peroxisome Proliferator ◽

Receptor Ligands ◽

Peroxisome Proliferator Activated Receptor ◽

Symptomatic Carotid ◽

Tissue Factor Pathway

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Anti-Atherogenic Role of Peroxisome Proliferator-Activated Receptor Ligands

Current Cardiology Reviews ◽

10.2174/1573403054021654 ◽

2005 ◽

Vol 1 (2) ◽

pp. 89-102 ◽

Author(s):

Julie Nigro ◽

Mandy Ballinger ◽

Narin Osman ◽

Anthony Dart ◽

Peter Little

Keyword(s):

Peroxisome Proliferator ◽

Receptor Ligands ◽

Peroxisome Proliferator Activated Receptor

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An update about the crucial role of stereochemistry on the effects of Peroxisome Proliferator-Activated Receptor ligands

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2019.05.012 ◽

2019 ◽

Vol 176 ◽

pp. 326-342 ◽

Author(s):

Antonio Laghezza ◽

Luca Piemontese ◽

Paolo Tortorella ◽

Fulvio Loiodice

Keyword(s):

Crucial Role ◽

Peroxisome Proliferator ◽

Receptor Ligands ◽

Peroxisome Proliferator Activated Receptor

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An Antidiabetic Thiazolidinedione Is a High Affinity Ligand for Peroxisome Proliferator-activated Receptor γ (PPARγ)

Journal of Biological Chemistry ◽

10.1074/jbc.270.22.12953 ◽

1995 ◽

Vol 270 (22) ◽

pp. 12953-12956 ◽

Cited By ~ 2366

Author(s):

Jürgen M. Lehmann ◽

Linda B. Moore ◽

Tracey A. Smith-Oliver ◽

William O. Wilkison ◽

Timothy M. Willson ◽

...

Keyword(s):

Peroxisome Proliferator ◽

Peroxisome Proliferator Activated Receptor ◽

High Affinity ◽

Affinity Ligand ◽

High Affinity Ligand

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Very-Long-Chain and Branched-Chain Fatty Acyl-CoAs Are High Affinity Ligands for the Peroxisome Proliferator-Activated Receptor α (PPARα)†

Biochemistry ◽

10.1021/bi060198l ◽

2006 ◽

Vol 45 (24) ◽

pp. 7669-7681 ◽

Author(s):

Heather A. Hostetler ◽

Ann B. Kier ◽

Friedhelm Schroeder

Keyword(s):

Peroxisome Proliferator ◽

Peroxisome Proliferator Activated Receptor ◽

Affinity Ligands ◽

High Affinity ◽

Branched Chain ◽

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Retinoic Acid Is a High Affinity Selective Ligand for the Peroxisome Proliferator-activated Receptor β/δ

Journal of Biological Chemistry ◽

10.1074/jbc.c300368200 ◽

2003 ◽

Vol 278 (43) ◽

pp. 41589-41592 ◽

Author(s):

Natacha Shaw ◽

Morten Elholm ◽

Noa Noy

Keyword(s):

Retinoic Acid ◽

Peroxisome Proliferator ◽

Peroxisome Proliferator Activated Receptor ◽

High Affinity ◽

Selective Ligand

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Activation of Mitogen-Activated Protein Kinases by Peroxisome Proliferator-Activated Receptor Ligands: An Example of Nongenomic Signaling

Molecular Pharmacology ◽

10.1124/mol.105.012260 ◽

2005 ◽

Vol 68 (4) ◽

pp. 933-941 ◽

Author(s):

Olivia S. Gardner ◽

Brian J. Dewar ◽

Lee M. Graves

Keyword(s):

Protein Kinases ◽

Peroxisome Proliferator ◽

Receptor Ligands ◽

Peroxisome Proliferator Activated Receptor ◽

Mitogen Activated Protein Kinases ◽

Mitogen Activated Protein

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Pulmonary Administration of GW0742, a High-Affinity Peroxisome Proliferator-Activated Receptor Agonist, Repairs Collapsed Alveoli in an Elastase-Induced Mouse Model of Emphysema

Biological and Pharmaceutical Bulletin ◽

10.1248/bpb.b15-00909 ◽

2016 ◽

Vol 39 (5) ◽

pp. 778-785 ◽

Author(s):

Chihiro Ozawa ◽

Michiko Horiguchi ◽

Tomomi Akita ◽

Yuki Oiso ◽

Kaori Abe ◽

...

Keyword(s):

Mouse Model ◽

Receptor Agonist ◽

Peroxisome Proliferator ◽

Peroxisome Proliferator Activated Receptor ◽

Pulmonary Administration ◽

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