scholarly journals Comparison of methods to estimate non-milk extrinsic sugars and their application to sugars in the diet of young adolescents

2005 ◽  
Vol 94 (1) ◽  
pp. 114-124 ◽  
Author(s):  
Sarah A. M. Kelly ◽  
Carolyn Summerbell ◽  
Andrew J. Rugg-Gunn ◽  
Ashley Adamson ◽  
Emma Fletcher ◽  
...  
Keyword(s):  
Dietary Intake ◽  
Critical Appraisal ◽  
Human Nutrition ◽  
Research Centre ◽  
Food Groups ◽  
Nutrition Research ◽  
Human Nutrition Research ◽  
Significant Difference ◽  
Dietary Surveys ◽  
Consistent Information

Consistent information on the non-milk extrinsic sugars (NMES) content of foods and the NMES intake by the population is required in order to allow comparisons between dietary surveys. A critical appraisal of methods of NMES estimation was conducted to investigate whether the different published methods for estimating the NMES content of foods lead to significantly different values for the dietary intake of NMES by children and to consider the relative practicality of each method. NMES values of foods were calculated using three different published descriptions of methods of NMES estimation, and the values were compared within food groups. Dietary intake values for English children aged 11–12 years were calculated using each method and compared in terms of overall NMES intake and the contribution of different food groups to NMES intake. There was no significant difference in the dietary intake of NMES in children between the method used in the National Diet and Nutrition Surveys (NDNS) (81·9 g/d; 95 % CI 79·0, 84·7) and a method developed by the Human Nutrition Research Centre (84·3 g/d; 95 % CI 81·4, 87·2) at Newcastle University, UK, although the latter gave slightly higher values. An earlier method used by the Ministry of Agriculture, Food and Fisheries gave significantly higher values than the other two methods (102·5 g/d; 95 % CI 99·3, 105·6; P<0·05). The method used in the NDNS surveys and the method used by the Human Nutrition Research Centre at Newcastle University are both thorough and detailed methods that give consistent results. However, the method used in the NDNS surveys was more straightforward to apply in practice and is the best method for a single uniform approach to the estimation of NMES.

Twenty years of research in the Human Nutrition Research Centre, Newcastle University, 1994-2014

2014 ◽  
Vol 39 (3) ◽  
pp. 266-275
Author(s):  
J. C. Mathers ◽  
T. R. Hill ◽  
E. Foster ◽  
A. J. Adamson ◽  
R. Valentine ◽  
...  
Keyword(s):  
Human Nutrition ◽  
Research Centre ◽  
Nutrition Research ◽  
Human Nutrition Research

The Human Nutrition Research Center on Aging

1989 ◽  
Vol 8 (3-4) ◽  
pp. 97-100
Author(s):  
Haworth Continuing Features Submission
Keyword(s):  
Human Nutrition ◽  
Research Center ◽  
Nutrition Research ◽  
Human Nutrition Research

scholarly journals Trimethylamine-N-Oxide (TMAO) Is Not Associated with Average Daily Intake of Red Meat or TMAO-Precursor Foods in a Generally Healthy Population

2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 37-37
Author(s):  
Kristen James ◽  
Erik Gertz ◽  
Charles Stephensen ◽  
Brian Bennett
Keyword(s):  
Energy Intake ◽  
Cystatin C ◽  
Daily Intake ◽  
Red Meat ◽  
Dietary Factors ◽  
Human Nutrition ◽  
Healthy Population ◽  
Fasting Plasma ◽  
Nutrition Research ◽  
Human Nutrition Research

Abstract Objectives The microbial metabolite trimethylamine n-oxide (TMAO) is associated with cardiovascular and renal disease. The dietary factors contributing to plasma TMAO concentrations are not well characterized in a generally healthy population unmedicated for metabolic diseases. The objective of this study was to assess the relationships among TMAO-precursor foods, TMAO, and classic cardiometabolic markers in a generally healthy population stratified for age, sex, and BMI. Methods Fasting plasma TMAO was quantified using liquid chromatography-mass spectrometry in 356 participants (n = 188 female, 18–65 yr, 18–40 BMI) enrolled in the cross-sectional Nutritional Phenotyping Study conducted as the USDA Western Human Nutrition Center. Diet was assessed by averaging 2 weekday and 1 weekend ASA-24hr recalls cleaned by NCBI guidelines. Fasting plasma analytes such as glucose, insulin, triglycerides, and cholesterol were measured using the Cobas Integra 400 Plus. Variables were transformed to conform to the normal distribution. Regression models assessing health parameters and TMAO were adjusted for age, sex, and the kidney function marker, cystatin C. Models assessing TMAO and diet variables were adjusted for age, sex, and energy intake. Composite variables describing average intake of red meat and TMAO-precursor foods were created by summing the appropriate ASA24 variables. Results TMAO was associated with age (P = 0.001), but not sex or BMI. A significant interaction (P = 0.006) between sex and age was used in all models. Of the variables analyzed, only refined grains and total energy intake were significantly associated with TMAO (r = −0.11, P = 0.04; r = 0.12, P = 0.03, respectively). Reduced renal function as assessed by circulating cystatin C concentrations was associated with plasma TMAO (r = 0.18, P &lt; 0.001). Average daily red meat consumption as well as average daily TMAO-precursor consumption was not significantly associated with TMAO (P = 0.137, P = 0.554, respectively). In contrast, average daily fiber intake was marginally related to TMAO (B = −0.11, SE = 0.01, P = 0.07). Conclusions In this generally healthy population, no relationship between red meat or TMAO-precursor foods and TMAO was identified. Funding Sources The Beef Checkoff (R01HL128572); USDA/ARS/Western Human Nutrition Research Center project funds (2032–51,000-025–00D).

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