Evaluation of bone mineral density and 25-(OH) vitamin D levels in middle-aged and elderly women with recurrent benign paroxysmal positional vertigo

2019 ◽  
Vol 140 (2) ◽  
pp. 89-93 ◽  
Author(s):  
Zhibin Wang ◽  
Guanghui Yao ◽  
Xiangming Tao ◽  
Jincui Zhang ◽  
Ting Zhang ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Vitamin D ◽  
Bone Mineral ◽  
Benign Paroxysmal Positional Vertigo ◽  
Elderly Women ◽  
Mineral Density ◽  
Positional Vertigo ◽  
Vitamin D Levels ◽  
25 Oh Vitamin D ◽  
Paroxysmal Positional Vertigo

scholarly journals Comparison of Bone Mineral Density with Biochemical Parameters and Prevalence of Osteopenia and Osteoporosis in South Indian Population

2018 ◽  
Vol 11 (4) ◽  
pp. 2209-2214
Author(s):  
P. Modagan ◽  
Santhi Silambanan ◽  
P. Gopinath Menon ◽  
P. Arunalatha
Keyword(s):  
Bone Mineral Density ◽  
Vitamin D ◽  
Bone Mineral ◽  
Serum Calcium ◽  
Biochemical Markers ◽  
South Indian Population ◽  
Mineral Density ◽  
Group I ◽  
Vitamin D Levels ◽  
25 Oh Vitamin D

Osteoporosis is identifying based on the bone mineral density (BMD). The bone mineral mass or BMD exposes the amount of minerals present in a particular region of bone tissue. BMD measurement by DEXA is consideredas gold standard, but it is very expensive. The people of developing countriesare not interested to check BMD until the occurrence offracture. Therefore present study focusing any association of routine biochemical markers with BMD in osteoporosis and also planning to identify disease distribution status in south India. We examined 773 participants BMD by DEXA scan and grouped into three, Group I (Normal bone mass, n=237), group II (Osteopenia, n=345) and group III (Osteoporosis, n=191). The serum calcium, phosphorous and alkaline phosphatase (ALP) were estimated by automated chemistry analyzer., and Serum 25(OH) vitamin D was analyzed by immunoassay system analyser. The prevalence of normal BMD, osteopenia and osteoporosis was 30.7%, 44.6%and 24.7% respectively.Between 60 and 69 years aged men having more prevalence of osteopenia and in women 50 to 59 years of age. While osteoporosis in men 50 to 59 years and in women’s were 60 to 69 years of age. The serum calcium, ALP and 25 (OH) vitamin D levels were statistically significant (p< 0.001) between the three groups.The higher percentage of low bone mineral density (osteopenia) is the alarming signalto the bone health and this could be continued leads to osteoporosis, which affects the quality of life. This study suggests to determining BMD along with biochemical markers are useful to identify osteoporosis in earlier stage. Therefore routine screening of BMD may prevent the risk of osteoporosis.

scholarly journals Hypovitaminosis D, Low Bone Mineral Density, and Diabetes Mellitus as Probable Risk Factors for Benign Paroxysmal Positional Vertigo in the Elderly

2019 ◽  
Vol 24 (03) ◽  
pp. e272-e277 ◽  
Author(s):  
Jessica Aparecida Bazoni ◽  
Daiane Soares Almeida Ciquinato ◽  
Audrey de Souza Marquez ◽  
Viviane de Souza Pinho Costa ◽  
Glória de Moraes Marchiori ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Bone Mineral Density ◽  
Vitamin D ◽  
Bone Mineral ◽  
Hypovitaminosis D ◽  
The Elderly ◽  
Mineral Density ◽  
Positional Vertigo ◽  
Significant Difference ◽  
Paroxysmal Positional Vertigo

Abstract Introduction Studies have found that elderly patients with benign paroxysmal positional vertigo (BPPV) may present low levels of vitamin D (25 (OH) D), changes in bone mineral density, and diabetes mellitus (DM). Objective: To investigate the possible association between BPPV, bone mineral density, hypovitaminosis D, 25 (OH) D and DM. Methods The sample consisted of 109 elderly subjects. The BPPV was verified by a standardized questionnaire and the Dix-Hallpike maneuver. Blood samples were collected for the investigation of 25 (OH) D serum levels. The bone mineral density was evaluated by means of a densitometer. Diabetes mellitus verification was performed using a self-reported questionnaire. Results Of the 109 participants, 17 had BPPV. There was a statistically significant difference between BPPV and gender (p = 0.027, phi = 0.222), with female representing 88.2% of those with BPPV. In the group with BPPV, there was a statistically significant difference for the amount of vitamin D found (p = 0.001) and for age (p = 0.001). In the elderly group with DM and BPPV, a difference was found for the standard deviation of the femur (p = 0.022) with posthoc Dunn, identifying the difference between diabetics with and without BPPV (p = 0.047). Conclusion Although no association was found (25 (OH) D levels) with BPPV in the general population of this study, it was observed that there was an association with bone mineral density in the elderly group with DM and BPPV, and, in the group with BPPV, there was an association between the amount of vitamin D and age.

OP0073 High Risk Fracture in Sarcoidosis Patients Despite Not Lowered Bone Mineral Density: Implication of Serum 25(OH) Vitamin D Levels

2013 ◽  
Vol 72 (Suppl 3) ◽  
pp. A75.1-A75
Author(s):  
N. Saidenberg-Kermanac’h ◽  
L. semerano ◽  
H. Nunes ◽  
D. Sadoun ◽  
X. Guillot ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Vitamin D ◽  
High Risk ◽  
Bone Mineral ◽  
Mineral Density ◽  
Vitamin D Levels ◽  
25 Oh Vitamin D

scholarly journals P114 Effect of vitamin D on parathyroid hormone, serum calcium and bone mineral density in patients with primary hyperparathyroidism being managed conservatively

Rheumatology ◽  
2021 ◽  
Vol 60 (Supplement_1) ◽  
Author(s):  
Mahrukh Khalid ◽  
Vismay Deshani ◽  
Khalid Jadoon
Keyword(s):  
Bone Mineral Density ◽  
Vitamin D ◽  
Parathyroid Hormone ◽  
Primary Hyperparathyroidism ◽  
Bone Mineral ◽  
Serum Calcium ◽  
Mineral Density ◽  
Neck Of Femur ◽  
Vitamin D Levels ◽  
Significant Difference

Abstract Background/Aims  Vitamin D deficiency is associated with more severe presentation of primary hyperparathyroidism (PTHP) with high parathyroid hormone (PTH) levels and reduced bone mineral density (BMD). We analyzed data to determine if vitamin D levels had any impact on PTH, serum calcium and BMD at diagnosis and 3 years, in patients being managed conservatively. Methods  Retrospective analysis of patients presenting with PHPT. Based on vitamin D level at diagnosis, patients were divided into two groups; vitamin D sufficient (≥ 50 nmol/L) and vitamin D insufficient (≤ 50 nmol/L). The two groups were compared for age, serum calcium and PTH levels at diagnosis and after mean follow up of 3 years. BMD at forearm and neck of femur (NOF) was only analyzed in the two groups at diagnosis, due to lack of 3 year’s data. Results  There were a total of 93 patients, 17 males, mean age 70; range 38-90. Mean vitamin D level was 73.39 nmol/L in sufficient group (n = 42) and 34.48 nmol/L in insufficient group (n = 40), (difference between means -38.91, 95% confidence interval -45.49 to -32.33, p &lt; 0.0001). There was no significant difference in age, serum calcium and PTH at the time of diagnosis. After three years, there was no significant difference in vitamin D levels between the two groups (mean vitamin D 72.17 nmol/L in sufficient group and 61.48 nmol/L in insufficient group). Despite rise in vitamin D level in insufficient group, no significant change was observed in this group in PTH and serum calcium levels. BMD was lower at both sites in vitamin D sufficient group and difference was statistically significant at NOF. Data were analyzed using unpaired t test and presented as mean ± SEM. Conclusion  50% of patients presenting with PHPT were vitamin D insufficient at diagnosis. Vitamin D was adequately replaced so that at 3 years there was no significant difference in vitamin D status in the two groups. Serum calcium and PTH were no different in the two groups at diagnosis and at three years, despite rise in vitamin D levels in the insufficient group. Interestingly, BMD was lower at forearm and neck of femur in those with sufficient vitamin D levels and the difference was statistically significant at neck of femur. Our data show that vitamin D insufficiency does not have any significant impact on PTH and calcium levels and that vitamin D replacement is safe in PHPT and does not impact serum calcium and PTH levels in the short term. Lower BMD in those with adequate vitamin D levels is difficult to explain and needs further research. Disclosure  M. Khalid: None. V. Deshani: None. K. Jadoon: None.

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