Temperature and pH-Responsive Polyacrylamide/Poly(Acrylic Acid) Interpenetrating Polymer Network Nanoparticles

2016 ◽  
Vol 55 (11) ◽  
pp. 1086-1098 ◽  
Author(s):  
Abraham G. Alvarado ◽  
Jorge Cortés ◽  
Lourdes A. Pérez-Carrillo ◽  
Martin Rabelero ◽  
Jesús Arellano ◽  
...  
Keyword(s):  
Acrylic Acid ◽  
Polymer Network ◽  
Interpenetrating Polymer Network ◽  
Ph Responsive ◽  
Poly Acrylic Acid

Synthesis and Characteristics of Interpenetrating Polymer Network Hydrogels Based on Konjac Glucomannan with Different Molecular Weights and Poly(acrylic acid)

2011 ◽  
Vol 393-395 ◽  
pp. 1004-1007
Author(s):  
Xue Yao ◽  
Xue Gang Luo ◽  
Ben Chao Han
Keyword(s):  
Acrylic Acid ◽  
Enzymatic Degradation ◽  
Drug Carrier ◽  
Polymer Network ◽  
Konjac Glucomannan ◽  
Interpenetrating Polymer Network ◽  
Swelling Ratio ◽  
Molecular Weights ◽  
Ft Ir ◽  
Poly Acrylic Acid

Konjac glucomannan with different molecular weights/poly(acrylic acid) hydrogels were prepared in this paper. The structure of the IPN hydrogels was characterized by FT-IR and SEM. The swelling ratio of these hydrogels showed they had pH-sensitive properties and the enzymatic degradation tests showed the hydrogels retain the enzymatic degradation character of KGM. Furthermore, hydrogel composed of native KGM degraded sharply in enzymatic degradation test and it had bigger swelling ratio and weight loss ratio than those hydrogels which composed of lower molecular weights KGM. Therefore, hydrogels composed of lower molecular weight might release drug more stable when they were used as drug carrier.

Water Behavior of Poly(acrylic acid)/ Poly (acrylonitrile) Semi-Interpenetrating Polymer Network Hydrogels

2004 ◽  
Vol 16 (4) ◽  
pp. 625-635 ◽  
Author(s):  
Seon Jeong Kim ◽  
Ki Jung Lee ◽  
Sang Min Lee ◽  
In Young Kim ◽  
Sun I. Kim
Keyword(s):  
Acrylic Acid ◽  
Polymer Network ◽  
Interpenetrating Polymer Network ◽  
Water Behavior ◽  
Poly Acrylonitrile ◽  
Poly Acrylic Acid

Optimal response surface design of Gum tragacanth-based poly[(acrylic acid)-co-acrylamide] IPN hydrogel for the controlled release of the antihypertensive drug losartan potassium

RSC Advances ◽  
2014 ◽  
Vol 4 (75) ◽  
pp. 39822-39829 ◽  
Author(s):  
Saruchi Saruchi ◽  
B. S. Kaith ◽  
Rajeev Jindal ◽  
Vaneet Kumar ◽  
Manpreet S. Bhatti
Keyword(s):  
Controlled Release ◽  
Acrylic Acid ◽  
Polymer Network ◽  
Interpenetrating Polymer Network ◽  
Losartan Potassium ◽  
Surface Design ◽  
Gum Tragacanth ◽  
Ph Conditions ◽  
Poly Acrylic Acid

The present study proposes the development and optimization of a new interpenetrating polymer network (IPN), consisting of Gum tragacanth, poly(acrylic acid) (PAA), and poly(acrylamide) (PAAm), for the in situ controlled release of losartan potassium under different pH conditions at 37 °C.

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