Pathogenesis: A New Therapist Personality Dimension Related to Therapeutic Effectiveness

1971 ◽  
Vol 35 (3) ◽  
pp. 252-260 ◽  
Author(s):  
Gary R. Vanden Bos ◽  
Bertram P. Karon
1998 ◽  
Vol 3 (1) ◽  
pp. 37-50 ◽  
Author(s):  
Thomas H. Rammsayer

Recent research suggests that individual differences in brain dopamine (DA) functioning may be related to the personality dimension of extraversion. The present study was designed to further elucidate the biological mechanisms underlying behavioral differences between extraverts and introverts. For this purpose, the differential effects of a pharmacologically induced blockade of mesolimbocortical DA D2 receptors on reaction-time performance were investigated in 24 introverted and 24 extraverted subjects. Introverts were found to be much more susceptible to pharmacologically induced changes in D2 receptor activity than extraverts. This finding provides additional experimental evidence for the notion that individual differences in D2 receptor responsivity may represent a neurobiological substratum for the personality dimension of extraversion.


2011 ◽  
Vol 73 (3) ◽  
pp. 260-265
Author(s):  
Toshinori BITO ◽  
Shun OHMORI ◽  
Mayuko YOSHIZAWA ◽  
Sanehito HARUYAMA ◽  
Yu SAWADA ◽  
...  

2020 ◽  
Vol 12 (1) ◽  
pp. 55-66
Author(s):  
Frans Laka Lazar

Everybody expects to become a mature person. The characteristic of mature persons are the ability to know and understand him/herself, to develop his/her pontentialities, to control his/her emotion, and to dealt with conflict and suffering. In order to reach the aim of religious formation, every formation house of religious congregation could develop good formation programs. The result of the study pointed out that some formation houses did not develop yet formation programs fully especially personality formation. The reality speaks to us that there are some religious men or women who are emotional, giving up as facing the difficulties and challenges, and less self-confidence. Therefore, the study could urge formation houses of religious congregation to be serious to develop personality dimension of relirious men or women.


2020 ◽  
Vol 27 (1) ◽  
pp. 154-169 ◽  
Author(s):  
Claudiu N. Lungu ◽  
Bogdan Ionel Bratanovici ◽  
Maria Mirabela Grigore ◽  
Vasilichia Antoci ◽  
Ionel I. Mangalagiu

Lack of specificity and subsequent therapeutic effectiveness of antimicrobial and antitumoral drugs is a common difficulty in therapy. The aim of this study is to investigate, both by experimental and computational methods, the antitumoral and antimicrobial properties of a series of synthesized imidazole-pyridine derivatives. Interaction with three targets was discussed: Dickerson-Drew dodecamer (PDB id 2ADU), G-quadruplex DNA string (PDB id 2F8U) and DNA strain in complex with dioxygenase (PDB id 3S5A). Docking energies were computed and represented graphically. On them, a QSAR model was developed in order to further investigate the structure-activity relationship. Results showed that synthesized compounds have antitumoral and antimicrobial properties. Computational results agreed with the experimental data.


2020 ◽  
Vol 318 (5) ◽  
pp. H1325-H1336
Author(s):  
Jaime Eugenín ◽  
Carolina Larraín ◽  
Patricio Zapata

Unilateral carotid body denervation has been proposed as treatment for sympathetic hyperactivity-related human disorders. Its therapeutic effectiveness for maintaining a persistent decrease in the sympathetic outflow activity will depend on the absence of compensatory chemoreflex plasticity in the remnant carotid and aortic afferents. Here, we suggest that the integrity of central afferents after carotid body denervation is essential to prevent the emergence of plastic functional changes on the contralateral “intact” carotid nerve.


2021 ◽  
Vol 9 (6) ◽  
Author(s):  
So Shimamura ◽  
Masafumi Saiki ◽  
Shuichiro Ide ◽  
Kazuki Masuda ◽  
Yoshinori Uchida ◽  
...  

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