A randomized crossover study to assess the pharmacokinetics of a novel amphetamine extended-release orally disintegrating tablet in healthy adults

2016 ◽  
Vol 128 (7) ◽  
pp. 648-655 ◽  
Author(s):  
Jeffrey G. Stark ◽  
Dorothy Engelking ◽  
Russ McMahen ◽  
Carolyn Sikes
Keyword(s):  
Crossover Study ◽  
Extended Release ◽  
Healthy Adults ◽  
Orally Disintegrating Tablet ◽  
Randomized Crossover Study

scholarly journals Effect of a Nutritional Supplement on Posaconazole Pharmacokinetics following Oral Administration to Healthy Volunteers

2006 ◽  
Vol 50 (5) ◽  
pp. 1881-1883 ◽  
Author(s):  
Angela Sansone-Parsons ◽  
Gopal Krishna ◽  
Angela Calzetta ◽  
David Wexler ◽  
Bhavna Kantesaria ◽  
...  
Keyword(s):  
Oral Administration ◽  
Crossover Study ◽  
Healthy Volunteers ◽  
Maximum Concentration ◽  
Nutritional Supplement ◽  
Healthy Adults ◽  
Time Curve ◽  
Fasted State ◽  
Concentration Time ◽  
Randomized Crossover Study

ABSTRACT We conducted a randomized, crossover study in healthy adults to examine the effects of a nutritional supplement (Boost Plus) on posaconazole pharmacokinetics. In this study, coadministration of posaconazole with Boost Plus increased the maximum concentration of posaconazole in serum and area under the concentration-time curve from 0 to 72 h values 3.4- and 2.6-fold, respectively, compared to those for the fasted state.

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