Impact of chronic medications in the perioperative period -mechanisms of action and adverse drug effects (part i)

2021 ◽  
Author(s):  
Ofelia L. Elvir-Lazo ◽  
Paul F White ◽  
Hillenn Cruz Eng ◽  
Firuz Yumul ◽  
Raissa Chua ◽  
...  
Keyword(s):  
Drug Effects ◽  
Perioperative Period ◽  
Mechanisms Of Action ◽  
Adverse Drug Effects ◽  
Chronic Medications

scholarly journals How Antidepressant Drugs Affect the Antielectroshock Action of Antiseizure Drugs in Mice: A Critical Review

2021 ◽  
Vol 22 (5) ◽  
pp. 2521
Author(s):  
Kinga K. Borowicz-Reutt
Keyword(s):  
Antiepileptic Drugs ◽  
Neurotrophic Factor ◽  
Antidepressant Drugs ◽  
Drug Effects ◽  
Mechanisms Of Action ◽  
Maximal Electroshock ◽  
Anticonvulsant Action ◽  
Mes Test ◽  
Seizure Model ◽  
Glial Derived Neurotrophic Factor

Depression coexists with epilepsy, worsening its course. Treatment of the two diseases enables the possibility of interactions between antidepressant and antiepileptic drugs. The aim of this review was to analyze such interactions in one animal seizure model—the maximal electroshock (MES) in mice. Although numerous antidepressants showed an anticonvulsant action, mianserin exhibited a proconvulsant effect against electroconvulsions. In most cases, antidepressants potentiated or remained ineffective in relation to the antielectroshock action of classical antiepileptic drugs. However, mianserin and trazodone reduced the action of valproate, phenytoin, and carbamazepine against the MES test. Antiseizure drug effects were potentiated by all groups of antidepressants independently of their mechanisms of action. Therefore, other factors, including brain-derived neurotrophic factor (BDNF) and glial-derived neurotrophic factor (GDNF) modulation, should be considered as the background for the effect of drug combinations.

Incidence rate of adverse drug effects in a hospital emergency unit and its associated factors

2010 ◽  
Vol 34 (6) ◽  
pp. 271-278
Author(s):  
S. Ramos Linares ◽  
P. DíazRuiz ◽  
J. Mesa Fumero ◽  
S. Núñez Díaz ◽  
M. Suárez González ◽  
...  
Keyword(s):  
Incidence Rate ◽  
Associated Factors ◽  
Drug Effects ◽  
Emergency Unit ◽  
Adverse Drug Effects ◽  
Hospital Emergency

scholarly journals Machine learning-based prediction of adverse drug effects: An example of seizure-inducing compounds

2017 ◽  
Vol 133 (2) ◽  
pp. 70-78 ◽  
Author(s):  
Mengxuan Gao ◽  
Hideyoshi Igata ◽  
Aoi Takeuchi ◽  
Kaoru Sato ◽  
Yuji Ikegaya
Keyword(s):  
Machine Learning ◽  
Drug Effects ◽  
Adverse Drug Effects

Impact of chronic medications in the perioperative period –anesthetic implications (Part II)

2021 ◽  
pp. 1-19
Author(s):  
Ofelia Loani Elvir-Lazo ◽  
Paul F White ◽  
Hillenn Cruz Eng ◽  
Firuz Yumul ◽  
Raissa Chua ◽  
...  
Keyword(s):  
Perioperative Period ◽  
Chronic Medications

Pharmacognostic, Phytochemical and Therapeutic Overview of three Allied Herbs used in Dentistry

2021 ◽  
Vol 11 (2) ◽  
pp. 121-125
Author(s):  
Deepak Prashar ◽  
Khushboo Jasra
Keyword(s):  
Chemical Composition ◽  
Drug Effects ◽  
Present Review ◽  
Adverse Drug Effects ◽  
Therapeutic Role

The dental herbs are very much essential for the treatment of many dental problems. They can be used as such or in the form of dental formulations. These dental formulations of the herbs have enormous economical importance too. Apart from the pharmaco-therapeutic role the pharmacognostic and it’s chemical composition is also essential. These parameters help to modify the formulations and to overcome the adverse drug effects associated with these. The present review work tries to highlight the Pharmacognostic and Phytochemical aspects of three dental herbs.

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