The Cobas Amplicor MTB Test for Detection of Mycobacterium tuberculosis Complex from Respiratory and Non-respiratory Clinical Specimens

2003 ◽  
Vol 35 (6-7) ◽  
pp. 372-377 ◽  
Author(s):  
Bodil Jönsson ◽  
Malin Ridell
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Mycobacterium Tuberculosis Complex ◽  
Tuberculosis Complex ◽  
Clinical Specimens

scholarly journals Detection of Mycobacterium tuberculosis complex and non-tuberculous mycobacteria by multiplex polymerase chain reactions

1999 ◽  
Vol 5 (1) ◽  
pp. 61-70
Author(s):  
A. S. Mustafa
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Mycobacterium Tuberculosis Complex ◽  
Clinical Isolates ◽  
Tuberculosis Complex ◽  
Clinical Specimens ◽  
Chain Reactions ◽  
Polymerase Chain Reactions ◽  
Polymerase Chain

The ability of two-band and three-band multiplex polymerase chain reactions to detect and differentiate Mycobacterium tuberculosis complex from non-tuberculous mycobacteria was evaluated. The polymerase chain reactions differentiated between M. tuberculosis and non-tuberculous mycobacteria when standard strains and clinical isolates of mycobacteria were tested. The sensitivity of the two-band and three-band techniques to detect M. tuberculosis in clinical specimens, compared with smear and/or culture, was 88% and 75% respectively. Although both techniques showed 100% specificity, the superior sensitivity of the two-band technique suggests that it could be more useful in the diagnosis of tuberculosis and in differentiating M. tuberculosis complex from non-tuberculous mycobacteria

Sign in / Sign up

Export Citation Format

Share Document