Association with polymorphic marmoset cytochrome P450 2C19 of in vivo hepatic clearances of chirally separated R-omeprazole and S-warfarin using individual marmoset physiologically based pharmacokinetic models

Cytochrome P450 2C19 ◽

Efavirenz clearances in vitro and in vivo in six cynomolgus monkeys associated with polymorphic cytochrome P450 2C9 and simulated by individual physiologically based pharmacokinetic models

Biopharmaceutics & Drug Disposition ◽

10.1002/bdd.2084 ◽

2017 ◽

Vol 38 (7) ◽

pp. 439-442 ◽

Cited By ~ 4

Author(s):

Masahiro Utoh ◽

Tomonori Miura ◽

Takashi Kusama ◽

Shotaro Uehara ◽

Makiko Shimizu ◽

...

Keyword(s):

Cytochrome P450 ◽

Pharmacokinetic Models ◽

Cytochrome P450 2C9 ◽

Cynomolgus Monkeys ◽

R-warfarin clearances from plasma associated with polymorphic cytochrome P450 2C19 and simulated by individual physiologically based pharmacokinetic models for 11 cynomolgus monkeys

Xenobiotica ◽

10.1080/00498254.2017.1288945 ◽

2017 ◽

Vol 48 (2) ◽

pp. 206-210 ◽

Cited By ~ 7

Author(s):

Masahiro Utoh ◽

Takashi Kusama ◽

Tomonori Miura ◽

Marina Mitsui ◽

Mirai Kawano ◽

...

Keyword(s):

Cytochrome P450 ◽

Pharmacokinetic Models ◽

Cynomolgus Monkeys ◽

Cytochrome P450 2C19 ◽

In Vitro to In Vivo Extrapolation of Metabolic Rate Constants for Physiologically Based Pharmacokinetic Models

Toxicokinetics and Risk Assessment ◽

10.1201/b14275-9 ◽

2016 ◽

pp. 185-210

Author(s):

Gregory L. Kedderis

Keyword(s):

Metabolic Rate ◽

Rate Constants ◽

Pharmacokinetic Models ◽

Physiologically Based ◽

In Vivo Extrapolation

Prediction of Pharmacokinetics Prior to In Vivo Studies. II. Generic Physiologically Based Pharmacokinetic Models of Drug Disposition

Journal of Pharmaceutical Sciences ◽

10.1002/jps.10128 ◽

2002 ◽

Vol 91 (5) ◽

pp. 1358-1370 ◽

Cited By ~ 208

Author(s):

Patrick Poulin ◽

Frank-Peter Theil

Keyword(s):

Drug Disposition ◽

In Vivo Studies ◽

Pharmacokinetic Models ◽

Combination of a biopharmaceutic classification system and physiologically based pharmacokinetic models to predict absorption properties of baicalein in vitro and in vivo

Journal of Traditional Chinese Medical Sciences ◽

10.1016/j.jtcms.2021.07.006 ◽

2021 ◽

Author(s):

Yang Liu ◽

Jing Sun ◽

Lin Ying Zhong ◽

Yu Li ◽

A Na Er ◽

...

Keyword(s):

Classification System ◽

Pharmacokinetic Models ◽

Absorption Properties ◽

Biopharmaceutic Classification System

Physiologically Based ◽

Using Physiologically-Based Pharmacokinetic Models to Incorporate Chemical and Non-Chemical Stressors into Cumulative Risk Assessment: A Case Study of Pesticide Exposures

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph9051971 ◽

2012 ◽

Vol 9 (5) ◽

pp. 1971-1983 ◽

Cited By ~ 7

Author(s):

Susan C. Wason ◽

Thomas J. Smith ◽

Melissa J. Perry ◽

Jonathan I. Levy

Keyword(s):

Risk Assessment ◽

Cumulative Risk ◽

Pharmacokinetic Models ◽

Pesticide Exposures ◽

Response to “The Link Between Pharmacodynamics and Physiologically Based Pharmacokinetic Models”

Clinical Pharmacology & Therapeutics ◽

10.1038/clpt.2012.216 ◽

2012 ◽

Vol 93 (2) ◽

pp. 152-152 ◽

Cited By ~ 5

Author(s):

A Rostami-Hodjegan

Keyword(s):

Pharmacokinetic Models ◽

Pharmacokinetic/Physiologically Based Pharmacokinetic Models in Integrated Risk Information System Assessments

Toxicokinetics and Risk Assessment ◽

10.1201/b14275-16 ◽

2006 ◽

pp. 301-348 ◽

Cited By ~ 2

Author(s):

Robert De Woskin ◽

Chadwick Thompson ◽

Weihsueh Chiu ◽

Paul Schlosser ◽

Carolyn Smallwood ◽

...

Keyword(s):

Information System ◽

Risk Information ◽

Pharmacokinetic Models ◽

Integrated Risk ◽

Are Physiologically Based Pharmacokinetic Models Reporting the Right Cmax? Central Venous Versus Peripheral Sampling Site

The AAPS Journal ◽

10.1208/s12248-015-9796-7 ◽

2015 ◽

Vol 17 (5) ◽

pp. 1268-1279 ◽

Cited By ~ 9

Author(s):

Helen Musther ◽

Katherine L. Gill ◽

Manoranjenni Chetty ◽

Amin Rostami-Hodjegan ◽

Malcolm Rowland ◽

...

Keyword(s):

Sampling Site ◽

Pharmacokinetic Models ◽

Central Venous ◽

Physiologically Based ◽

The Right

Physiologically Based Pharmacokinetic Models in Reproductive and Developmental Toxicology

Reproductive and Developmental Toxicology ◽

10.1016/b978-0-12-804239-7.00004-4 ◽

2017 ◽

pp. 51-65

Author(s):

Kannan Krishnan ◽

Sandrine Fleur Chebekoue

Keyword(s):

Pharmacokinetic Models ◽

Developmental Toxicology ◽