R-warfarin clearances from plasma associated with polymorphic cytochrome P450 2C19 and simulated by individual physiologically based pharmacokinetic models for 11 cynomolgus monkeys

Xenobiotica ◽  
2017 ◽  
Vol 48 (2) ◽  
pp. 206-210 ◽  
Author(s):  
Masahiro Utoh ◽  
Takashi Kusama ◽  
Tomonori Miura ◽  
Marina Mitsui ◽  
Mirai Kawano ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Pharmacokinetic Models ◽  
Cynomolgus Monkeys ◽  
Physiologically Based Pharmacokinetic Models ◽  
Physiologically Based Pharmacokinetic ◽  
Cytochrome P450 2C19 ◽  
Physiologically Based

scholarly journals Are Physiologically Based Pharmacokinetic Models Reporting the Right Cmax? Central Venous Versus Peripheral Sampling Site

2015 ◽  
Vol 17 (5) ◽  
pp. 1268-1279 ◽  
Author(s):  
Helen Musther ◽  
Katherine L. Gill ◽  
Manoranjenni Chetty ◽  
Amin Rostami-Hodjegan ◽  
Malcolm Rowland ◽  
...  
Keyword(s):  
Sampling Site ◽  
Pharmacokinetic Models ◽  
Central Venous ◽  
Physiologically Based Pharmacokinetic Models ◽  
Physiologically Based Pharmacokinetic ◽  
Physiologically Based ◽  
The Right
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