Short Communication RESIDENCE TIME DISTRIBUTION IN THE EXTRA CAPILLARY SPACE OF HOLLOW FIBER BIOREACTORS

1995 ◽  
Vol 138 (1) ◽  
pp. 239-247
Author(s):  
CYNTHIA B. ELIASI ◽  
MILIND S. PATOLE ◽  
ANANT Y. PATKAR ◽  
RAGHUNATH A. MASHELKAR
Author(s):  
Matthew Coblyn ◽  
Agnieszka Truszkowska ◽  
Goran Jovanovic

Current hemodialysis techniques rely on hollow-fiber tubes in a tube-and-shell operating approach. The method works satisfactorily; but, technological advantages of this method are already exhausted for a long time. Additional improvements are needed which could provide a way towards improving patient health and quality of life. Patients with renal failure undergo intense filtration sessions approximately three times a week leaving them fatigued. Large oscillations in concentration of various solutes within blood cause detrimental consequences on the overall health of patients.


2021 ◽  
Vol 32 (2) ◽  
pp. 611-618
Author(s):  
Atena Dehghani Kiadehi ◽  
Mikel Leturia ◽  
Franco Otaola ◽  
Aissa Ould-Dris ◽  
Khashayar Saleh

Metals ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 430
Author(s):  
Changyou Ding ◽  
Hong Lei ◽  
Hong Niu ◽  
Han Zhang ◽  
Bin Yang ◽  
...  

The residence time distribution (RTD) curve is widely applied to describe the fluid flow in a tundish, different tracer mass concentrations and different tracer volumes give different residence time distribution curves for the same flow field. Thus, it is necessary to have a deep insight into the effects of the mass concentration and the volume of tracer solution on the residence time distribution curve. In order to describe the interaction between the tracer and the fluid, solute buoyancy is considered in the Navier–Stokes equation. Numerical results show that, with the increase of the mass concentration and the volume of the tracer, the shape of the residence time distribution curve changes from single flat peak to single sharp peak and then to double peaks. This change comes from the stratified flow of the tracer. Furthermore, the velocity difference number is introduced to demonstrate the importance of the density difference between the tracer and the fluid.


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