The development of network technology to integrate network health information resources, regulate commerce, associations and other web services and form a diversified public health network information services has a significant meaning for public health network information guidance. This paper proposed the concept of public health information resources service system based on the cloud computing technology and described the location of public health information resources cloud services and cloud deployment model. And we also build an overall framework of information resource cloud service system in which the characteristics and processes of information resource layer, service layer, user layer and evaluation layer were designed.