scholarly journals Early radiological progression remains associated with long-term joint damage in real-world rheumatoid arthritis patients treated to the target of remission

Author(s):  
GA Versteeg ◽  
LMM Steunebrink ◽  
HE Vonkeman ◽  
PM Ten Klooster ◽  
AE Van Der Bijl ◽  
...  
Author(s):  
Kathryn Biddle ◽  
Nidhi Sofat

Pain is a debilitating feature of rheumatoid arthritis (RA) and is often described by patients as their most important symptom. Rheumatoid arthritis pain has traditionally been attributed solely to joint inflammation, however despite the advent of increasingly effective disease modifying agents, patients continue to report pain at long term follow up. The cause for ongoing pain is multifactorial and includes joint damage and pain sensitisation. In this book chapter, we will describe the mechanisms underlying the distinct components of pain which are manifest in rheumatoid arthritis and discuss why a thorough assessment of pain is vital to target treatments appropriately.


1986 ◽  
Vol 45 (5) ◽  
pp. 373-378 ◽  
Author(s):  
D L Scott ◽  
B L Coulton ◽  
A J Popert

2006 ◽  
Vol 13 (2-4) ◽  
pp. 295-297 ◽  
Author(s):  
Catalina Orozco ◽  
Nancy J. Olsen

Rheumatoid arthritis (RA) is the most common form of inflammatory arthritis that affects the adult population. Early diagnosis and treatment are the cornerstones to prevent joint damage and avoid long-term costs and disability. This article reviews the limitations of the currently available tools for the evaluation of patients with early arthritis, including clinical assessment, serologic markers and imaging modalities. It also discusses gene expression analysis, a newer and potentially promising approach to the early diagnosis of RA.


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