Confirmatory Factor Analysis of the Quality of Life in Alzheimer’s Disease Scale in Patients with Alzheimer’s Disease

2014 ◽  
Vol 40 (3) ◽  
pp. 266-279 ◽  
Author(s):  
María Gómez-Gallego ◽  
Juan Gomez-García ◽  
Manuel Ato-García
Keyword(s):  
Quality Of Life ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Factor Analysis ◽  
Confirmatory Factor Analysis ◽  
Confirmatory Factor

scholarly journals Evaluating the measurement properties of the 26-item Expanded Prostate Cancer Index Composite (EPIC-26) with a multicenter cohort

2019 ◽  
Vol 14 (4) ◽  
Author(s):  
R. Trafford Crump ◽  
Alex Peterson ◽  
Camille Charbonneau ◽  
Kevin V. Carlson ◽  
Jason M. Sutherland ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Prostate Cancer ◽  
Factor Analysis ◽  
Confirmatory Factor Analysis ◽  
Construct Validity ◽  
Localized Prostate Cancer ◽  
Measurement Properties ◽  
Confirmatory Factor ◽  
Ceiling Effects

Introduction: We aimed to evaluate the psychometric properties of the 26-item Expanded Prostate Cancer Index Composite (EPIC-26) for measuring the quality of life in patients treated for localized prostate cancer. The EPIC-26 is a patient-reported outcome instrument recommended for use with patients treated for localized prostate cancer. Methods: This study is based on data collected prospectively between September 2014 and February 2017 in Alberta, Canada. Men were treated with either radical prostatectomy or radiation therapy and administered the EPIC-26. Responses to the EPIC-26 were the primary outcome. Construct validity was measured using confirmatory factor analysis. Reliability was measured using Chronbach’s alpha and item-total correlation. Ceiling and floor effects were also investigated. Results: EPIC-26 response data from 205 participants (prostatectomy =138; radiation=60; both=7) were used in this analysis. The EPIC-26 was administered an average of 33.8 weeks after treatment. The confirmatory factor analysis model did not meet the threshold for adequate fit. Several items had near-zero factor loadings and were non-significant. Four out of the EPIC- 26’s five domains met the acceptable reliability threshold based on Cronbach’s alpha. Ceiling effects were observed in four out of five domains. Conclusions: The EPIC-26 demonstrated poor construct validity, adequate reliability, and large ceiling effects. Several issues were observed, suggesting that the instrument’s five domains were not well-defined by their respective items. The original EPIC’s conceptual framework should be reviewed and the shortened instrument revised to improve its performance for measuring post-treatment quality of life.

Neuropsychiatric symptom clusters of Alzheimer's disease in Hong Kong Chinese: prevalence and confirmatory factor analysis of the Neuropsychiatric Inventory

2012 ◽  
Vol 24 (9) ◽  
pp. 1465-1473 ◽  
Author(s):  
Sheung-Tak Cheng ◽  
Timothy Kwok ◽  
Linda C. W. Lam
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Factor Analysis ◽  
Confirmatory Factor Analysis ◽  
Factor Model ◽  
Community Dwelling ◽  
Symptom Clusters ◽  
Neuropsychiatric Inventory ◽  
Measurement Models ◽  
Confirmatory Factor

ABSTRACTBackground: The aim of this study was to investigate the clustering of symptoms on the Neuropsychiatric Inventory (NPI) and the relative prevalence of symptom clusters in mild and moderate Alzheimer's disease (AD).Methods: Confirmatory factor analysis (CFA) was performed on the polychoric correlation matrix of 12 NPI items (scored yes or no) using the weighted least squares with mean and variance adjustment (WLSMV) estimator in Mplus (N = 224 community-dwelling Chinese persons with mild/moderate AD). Severity of AD was determined by Clinical Dementia Rating scores. The relative model fit of three competing measurement models (also known as factor structures) was tested using a modified χ2 difference test. Prevalence rates across mild and moderate stages were compared using χ2 tests. Furthermore, the measurement model of choice was cross-validated in an independent sample of 181 community-dwelling persons with dementia.Results: CFA supported a four-factor model, namely behavioral problems (agitation/aggressiveness, disinhibition, irritability, and aberrant motor behavior), psychosis (delusions and hallucinations), mood disturbance (depression, anxiety, sleep, appetite, and apathy), and euphoria (a stand-alone item that is equivalent to the factor). The most prevalent symptom clusters were behavioral (72%) and mood (69%) disturbances, followed by psychosis (45%). Euphoria was rare (6%). All syndromes were more prevalent in moderate than in mild stage, except for euphoria. In addition, the four-factor model was replicated in the cross-validation sample.Conclusions: The four syndromes provide a parsimonious conceptualization of neuropsychiatric symptoms corresponding to clinical observations and neurochemical changes of the disease. The independent replication in the second sample supports generalization of the four-factor model in Chinese persons with AD.

Components of quality of life in a sample of patients with lupus: a confirmatory factor analysis and Rasch modeling of the LupusQoL

2017 ◽  
Vol 36 (8) ◽  
pp. 1789-1795 ◽  
Author(s):  
Ana-Belén Meseguer-Henarejos ◽  
Juan-José Gascón-Cánovas ◽  
José-Antonio López-Pina
Keyword(s):  
Quality Of Life ◽  
Factor Analysis ◽  
Confirmatory Factor Analysis ◽  
Rasch Modeling ◽  
Confirmatory Factor

scholarly journals The Unique Relationship between Quality of Life and Consumer Trust in Market-Related Institutions among Financially Constrained Consumers in a Developing Country

2009 ◽  
Vol 28 (1) ◽  
pp. 56-70 ◽  
Author(s):  
Ahmet Ekici ◽  
Mark Peterson
Keyword(s):  
Quality Of Life ◽  
Factor Analysis ◽  
Confirmatory Factor Analysis ◽  
Developing Country ◽  
Poverty Line ◽  
Consumer Trust ◽  
Subjective Quality Of Life ◽  
Confirmatory Factor ◽  
Unique Relationship

This study focuses on how relationships among constructs representing (1) consumer trust in market-related institutions (CTMRI), (2) distrust for individuals (DFI), and (3) subjective quality of life (QOL) differ across groups separated by the poverty line in a developing country (Turkey). A comparison of models across the two groups using multisample confirmatory factor analysis indicates that there is a correlation only between CTMRI and QOL for consumers below the poverty line (r = .43); there are no correlations between any of the three constructs for consumers above the poverty line. Accordingly, there is a unique relationship between QOL and CTMRI among financially constrained consumers in a developing country. Below the poverty line, consumers with lower trust in market-related institutions tend to report lower QOL, while those with higher trust in market-related institutions tend to report higher QOL.

scholarly journals Familism Scale: Confirmatory Factor Analysis in a Sample of Caregivers of Older Adults

2019 ◽  
Vol 29 ◽  
Author(s):  
Deusivania Vieira da Silva Falcão ◽  
Daniel Paulson ◽  
Manuel Herrera Legon ◽  
Carolina Irurita-Ballesteros
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Factor Analysis ◽  
Confirmatory Factor Analysis ◽  
Factor Structure ◽  
Depression Scale ◽  
Epidemiological Studies ◽  
Filial Obligation ◽  
Satisfaction Scale ◽  
Confirmatory Factor

Abstract The objective of this study was to translate and confirm the factor structure of the Familism Scale in the Brazilian Portuguese version. The sample included 716 Brazilian caregivers providing care to their own aging parents with Alzheimer’s Disease. The measures included the Familism Scale, the Filial Obligation Scale, the Life Satisfaction scale and the Center for Epidemiological Studies-Depression scale (CES-D). The questionnaire was individually filled online with use of the survey software package Qualtrics. Confirmatory Factor Analysis was used to examine the factor structure. The modified model demonstrated adequate fit (RMSEA = .063, CFI = .912). The hypotheses concerning convergence and divergence of validity from relevant variables were corroborated. These results support the use of the modified Familism Scale including twelve items and two factors with acceptable psychometric properties in a sample of Brazilian caregivers with Alzheimer’s Disease.

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