Nanon-Propylsulfonated Magnetic γ-Fe2O3as an Efficient and Reusable Catalyst for the SynthesisO-Isopropylidene Derivatives of Carbohydrates

2013 ◽  
Vol 32 (4) ◽  
pp. 249-258 ◽  
Author(s):  
Xiaoran Zhang ◽  
Changqiang Zhang
Keyword(s):  
Reusable Catalyst ◽  
Isopropylidene Derivatives ◽  
Derivatives Of

Synthesis and Antimicrobial activities of Some Polyphenol compounds by Nano ZnO-TBAB as a Heterogeneous Catalytic Media

2020 ◽  
Vol 17 ◽  
Author(s):  
Rahele Bargebid ◽  
Ali Khalafi-Nezhad ◽  
Kamiar Zomorodian ◽  
Leila Zamani ◽  
Ali Ahmadinejad ◽  
...  
Keyword(s):  
Antibacterial Activities ◽  
Antimicrobial Activities ◽  
Reusable Catalyst ◽  
Nano Zno ◽  
Antifungal Activities ◽  
Chemical Structures ◽  
Heterogeneous Catalytic ◽  
Solvent Free Conditions ◽  
New Compounds ◽  
Derivatives Of

Introduction: Mannich reaction is a typical example of a three-component condensation reaction and the chemistry of Mannich bases has been the matter of search by researchers. Here an efficient procedure for the synthesis of some new Mannich derivatives of simple phenols is described. Methods: In this procedure a microwave-assisted and solvent less condensation were done between different phenols, secondary amines and paraformaldehyde. The reactions proceed in the presence of catalytic amount of nano ZnO and tetrabutylammonium bromide (TBAB) in excellent yields. 10 new compounds were synthesized (A1-A10). Chemical structures of all new compounds were confirmed by different spectroscopic methods. We optimized the chemical reactions in different conditions. Optimization reactions were done in the presence of different mineral oxides, different amount of TBAB and also different solvents. Nano ZnO and TBAB in catalytic amounts and solvent free conditions were the best conditions. All the synthesized compounds were screened for their antimicrobial activities. Antifungal and antibacterial activities of the synthesized compounds were evaluated against some Candida, filaments fungi, gram positive and gram negative bacteria by broth micro dilution method as recommended by CLSI. Results: The result showed that compounds A2, A3 and A4 against most of the tested Candida species and compounds A5 and A7 against C. parapsilosis and C. tropicalis, exhibited considerable antifungal activities. Also Compounds A8 and A10 showed desirable antifungal activities against C. neoformance and C. parapsilosis, respectively. The antibacterial activities of the synthesized compounds were also evaluated. Compounds A6 - A10 against E. Fecalis and compounds A5, A7, A9 and A10 against P. aeruginosa showed desirable antibacterial activities. Discussion: We have synthesized some new Mannich adducts of poly-hydroxyl phenols in the presence of nano-ZnO as a reusable catalyst, with the hope of discovering new lead compounds serving as potent antimicrobial agents. The advantages of this method are generality, high yields with short reaction times, simplicity, low cost and matching with green chemistry protocols. The antimicriobial studies of Mannich derivatives of phenols showed desirable results in vitro.

Cyclic phosphites based on O-isopropylidene derivatives of D-mannitol

1970 ◽  
Vol 19 (7) ◽  
pp. 1580-1582
Author(s):  
O. V. Voskresenskaya ◽  
P. A. Kirpichnikov ◽  
�. T. Mukmenev
Keyword(s):  
Isopropylidene Derivatives ◽  
Derivatives Of

426. Aspects of stereochemistry. Part XI. Isopropylidene derivatives of L-arabitol and ribitol

1963 ◽  
pp. 2291 ◽  
Author(s):  
M. A. Bukhari ◽  
A. B. Foster ◽  
J. Lehmann ◽  
J. M. Webber ◽  
J. H. Westwood
Keyword(s):  
Isopropylidene Derivatives ◽  
Derivatives Of

Some O-isopropylidene derivatives of D-ribose diethyl dithioacetal

1969 ◽  
Vol 47 (15) ◽  
pp. 2889-2891 ◽  
Author(s):  
D. G. Lance ◽  
W. A. Szarek ◽  
J. K. N. Jones
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Copper Sulfate ◽  
Spectroscopic Methods ◽  
Isopropylidene Derivatives ◽  
Derivatives Of ◽  
Nuclear Magnetic

Acetonation of D-ribose diethyl dithioacetal using anhydrous copper sulfate as catalyst gives predominantly 2,4- and 4,5-O-isopropylidene derivatives. The structures of the compounds were established by chemical and nuclear magnetic resonance spectroscopic methods.

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