scholarly journals Treatment of climacteric symptoms with an ammonium succinate-based dietary supplement: a randomized, double-blind, placebo-controlled trial

2016 ◽  
Vol 32 (sup2) ◽  
pp. 64-68 ◽  
Author(s):  
V. E. Radzinskii ◽  
I. V. Kuznetsova ◽  
Y. B. Uspenskaya ◽  
N. B. Repina ◽  
Y. K. Gusak ◽  
...  
Keyword(s):  
Dietary Supplement ◽  
Controlled Trial ◽  
Climacteric Symptoms ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Ammonium Succinate

scholarly journals Effect of a dietary supplement containing kurozu (a Japanese traditional health drink) concentrate on several obesity-related parameters in obese Japanese adults: a randomized, double-blind, placebo-controlled trial

2013 ◽  
Vol 3 (8) ◽  
pp. 310 ◽  
Author(s):  
Naobumi Hamadate ◽  
Ken-ichiro Nakamura ◽  
Motoko Hirai ◽  
Tetsuro Yamamoto ◽  
Hideyo Yamaguchi ◽  
...  
Keyword(s):  
Placebo Group ◽  
Dietary Supplement ◽  
Controlled Trial ◽  
Subcutaneous Fat ◽  
Abdominal Fat ◽  
Double Blind ◽  
Visceral Fat Area ◽  
Double Blind Placebo ◽  
Traditional Health ◽  
Total Fat

Objective: This study was undertaken to examine the Kurozu concentrate (KC) based dietary supplement on several obesity-related parameters in obese Japanese male and female adults.Background: Kurozu, which is a specific type of rice vinegar produced by fermentation of unpolished brown rice, has long been used as a traditional health food and folk medicine in Japan. A recent animal study and our preliminary human study suggest that the KC supplement has potential for use in the management of obesity.Materials and Methods: A 12-week, randomized, double-blind, placebo-controlled trial was conducted involving 48 Japanese adult subjects (28 males and 20 females) with obesity. Subjects were either assigned to the group consuming the KC supplement for 12 weeks (870mg/day; 480 mg/day as KC) (n=24; 14 males and 10 females) or the placebo group (n=24; 14 males and 10 females). All test participants were assessed using several obesity-related parameters, including body weight, BMI, waist circumference, and abdominal fat computed tomography (CT) sections. These measurements took place at baseline and at week 12. Results: At week 12, a significant decrease in body weight (P<0.043) and nearly significant decreased values of BMI (P=0.052) were observed in the KC group compared to the placebo group. The reduction in waist circumference at week 12 within the KC group was not significantly greater than the placebo group. Examination of abdominal CT sections around the navel indicated that, although most of the values of the total fat area, subcutaneous fat area, and visceral fat area for both of the placebo and KC groups significantly increased during the 12-week intervention, the magnitude of increase in the total fat area for all subjects and that of the total fat area, subcutaneous fat area, and visceral fat area for females on one or more of three CT sections were significantly lower in the KC group than the placebo group (P<0.05).Conclusion: Although the results are not definitive, KC supplementation may have potential for improving some obesity-related parameters in obese subjects, particularly females.Key words: Kurozu concentrate (KC), KC-based dietary supplement (KC supplement), abdominal obesity-related parameters, body mass index (BMI), computed tomography (CT), abdominal fat

scholarly journals The Relieving Effects of BrainPower Advanced, a Dietary Supplement, in Older Adults with Subjective Memory Complaints: A Randomized, Double-Blind, Placebo-Controlled Trial

2016 ◽  
Vol 2016 ◽  
pp. 1-16 ◽  
Author(s):  
Jingfen Zhu ◽  
Rong Shi ◽  
Su Chen ◽  
Lihua Dai ◽  
Tian Shen ◽  
...  
Keyword(s):  
Older Adults ◽  
Dietary Supplement ◽  
Controlled Trial ◽  
Memory Function ◽  
Memory Loss ◽  
Subjective Memory Complaints ◽  
Subjective Memory ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Memory Complaints

Subjective memory complaints (SMCs) are common in older adults that can often predict further cognitive impairment. No proven effective agents are available for SMCs. The effect of BrainPower Advanced, a dietary supplement consisting of herbal extracts, nutrients, and vitamins, was evaluated in 98 volunteers with SMCs, averaging 67 years of age (47–88), in a randomized, double-blind, placebo-controlled trial. Subjective hypomnesis/memory loss (SML) and attention/concentration deficits (SAD) were evaluated before and after 12-week supplementation of BrainPower Advanced capsules (n=47) or placebo (n=51), using a 5-point memory questionnaire (1 = no/slight, 5 = severe). Objective memory function was evaluated using 3 subtests of visual/audio memory, abstraction, and memory recall that gave a combined total score. The BrainPower Advanced group had more cases of severe SML (severity⩾3) (44/47) and severe SAD (43/47) than the placebo group (39/51 and 37/51, < 0.05, < 0.05, resp.) before the treatment. BrainPower Advanced intervention, however, improved a greater proportion of the severe SML (29.5%)(13/44) (P<0.01) and SAD (34.9%)(15/43)(P<0.01) than placebo (5.1% (2/39) and 13.5% (5/37), resp.). Thus, 3-month BrainPower Advanced supplementation appears to be beneficial to older adults with SMCs.

Dietary supplement increases anagen hair rate in women with telogen effluvium: results of a double-blind, placebo-controlled trial

Therapy ◽  
2007 ◽  
Vol 4 (1) ◽  
pp. 59-65 ◽  
Author(s):  
Nadine Lengg ◽  
Barbara Heidecker ◽  
Burkhardt Seifert ◽  
Ralph M Trüeb
Keyword(s):  
Dietary Supplement ◽  
Controlled Trial ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Anagen Hair

Effect of a Mangosteen Dietary Supplement on Human Immune Function: A Randomized, Double-Blind, Placebo-Controlled Trial

2009 ◽  
Vol 12 (4) ◽  
pp. 755-763 ◽  
Author(s):  
Yu-Ping Tang ◽  
Peng-Gao Li ◽  
Miwako Kondo ◽  
Hong-Ping Ji ◽  
Yan Kou ◽  
...  
Keyword(s):  
Immune Function ◽  
Dietary Supplement ◽  
Controlled Trial ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Human Immune

scholarly journals Reduction of common cold symptoms by encapsulated juice powder concentrate of fruits and vegetables: a randomised, double-blind, placebo-controlled trial

2010 ◽  
Vol 105 (1) ◽  
pp. 118-122 ◽  
Author(s):  
Stephanie Roll ◽  
Marc Nocon ◽  
Stefan N. Willich
Keyword(s):  
Dietary Supplement ◽  
Common Cold ◽  
Fruits And Vegetables ◽  
Healthcare Professionals ◽  
Controlled Trial ◽  
University Hospital ◽  
Primary Analysis ◽  
Double Blind ◽  
Double Blind Placebo ◽  
The Mean

Dietary supplements have been suggested in the prevention of the common cold, but previous investigations have been inconsistent. The present study was designed to determine the preventive effect of a dietary supplement from fruits and vegetables on common cold symptoms. In a randomised, double-blind, placebo-controlled trial, healthcare professionals (mainly nursing staff aged 18–65 years) from a university hospital in Berlin, Germany, were randomised to four capsules of dietary supplement (Juice Plus+®) or matching placebo daily for 8 months, including a 2-month run-in period. The number of days with moderate or severe common cold symptoms within 6 months (primary outcome) was assessed by diary self-reports. We determined means and 95 % CI, and differences between the two groups were analysed by ANOVA. A total of 529 subjects were included into the primary analysis (Juice Plus+®: 263, placebo: 266). The mean age of the participants was 39·9 (sd 10·3) years, and 80 % of the participants were female. The mean number of days with moderate or severe common cold symptoms was 7·6 (95 % CI 6·5, 8·8) in the Juice Plus+® group and 9·5 (8·4, 10·6) in the placebo group (P = 0·023). The mean number of total days with any common cold symptoms was similar in the Juice Plus+® and in the placebo groups (29·4 (25·8, 33·0) v. 30·7 (27·1, 34·3), P = 0·616). Intake of a dietary supplement from fruits and vegetables was associated with a 20 % reduction of moderate or severe common cold symptom days in healthcare professionals particularly exposed to patient contact.

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