Perfectionism is the refusal to accept any standard short of perfect. Perfectionist students might strive for ‘faultless performance, meticulous attention to detail and high levels of competency' (Humphris & Kaney, 1998). In a field as complex and advanced as medicine, faultless performance is unrealistically expected. This chapter will discuss how the rigours of medical school promote perfectionistic behaviours in students. What is perfectionism? How does perfectionism in medical school affect students? How can educators and administrators identify perfectionism, provide psychoeducation, or address maladaptive perfectionism? How can students address perfectionism? It is essential to recognise perfectionism in medical students as research has shown that maladaptive perfectionism has been correlated to physician suicide (Scutti, 2014). The chapter concludes with recommendations on how students and medical educators can employ strategies to promote sound mental health and wellbeing during medical school.