miR-22-3p regulates muscle fiber-type conversion through inhibiting AMPK/SIRT1/PGC-1α pathway

2020 ◽  
pp. 1-8
Author(s):  
Wanxue Wen ◽  
Xiaoling Chen ◽  
Zhiqing Huang ◽  
Daiwen Chen ◽  
Ping Zheng ◽  
...  
2013 ◽  
Vol 10 (1) ◽  
pp. 46 ◽  
Author(s):  
Kosaku Higashino ◽  
Tetsuya Matsuura ◽  
Katsuyoshi Suganuma ◽  
Kiminori Yukata ◽  
Toshihiko Nishisho ◽  
...  

2019 ◽  
Vol 16 (1) ◽  
Author(s):  
Luting Wu ◽  
Li Ran ◽  
Hedong Lang ◽  
Min Zhou ◽  
Li Yu ◽  
...  

2016 ◽  
Vol 480 (4) ◽  
pp. 669-674 ◽  
Author(s):  
Fei Ying ◽  
Liang Zhang ◽  
Guowei Bu ◽  
Yuanzhu Xiong ◽  
Bo Zuo

Biologia ◽  
2019 ◽  
Vol 74 (6) ◽  
pp. 709-715 ◽  
Author(s):  
Xiaoling Chen ◽  
Gang Jia ◽  
Hua Zhao ◽  
Guangmang Liu ◽  
Zhiqing Huang

2013 ◽  
Vol 634-638 ◽  
pp. 1263-1267
Author(s):  
Lin Su ◽  
Hui Li ◽  
Xue Xin ◽  
Yan Duan ◽  
Xiao Qing Hua ◽  
...  

Muscle fiber is the basic unit of muscle tissue, this paper summarized the types of muscle fiber of animals, the influence factors of muscle fiber type distribution and the muscle fiber type conversion in the process of growth constantly. Discuss the important effect of muscle fiber type on meat quality.


2014 ◽  
Vol 207 (6) ◽  
pp. 753-766 ◽  
Author(s):  
Duo Zhang ◽  
Xiaoyun Wang ◽  
Yuying Li ◽  
Lei Zhao ◽  
Minghua Lu ◽  
...  

It is known that thyroid hormone (TH) is a major determinant of muscle fiber composition, but the molecular mechanism by which it does so remains unclear. Here, we demonstrated that miR-133a1 is a direct target gene of TH in muscle. Intriguingly, miR-133a, which is enriched in fast-twitch muscle, regulates slow-to-fast muscle fiber type conversion by targeting TEA domain family member 1 (TEAD1), a key regulator of slow muscle gene expression. Inhibition of miR-133a in vivo abrogated TH action on muscle fiber type conversion. Moreover, TEAD1 overexpression antagonized the effect of miR-133a as well as TH on muscle fiber type switch. Additionally, we demonstrate that TH negatively regulates the transcription of myosin heavy chain I indirectly via miR-133a/TEAD1. Collectively, we propose that TH inhibits the slow muscle phenotype through a novel epigenetic mechanism involving repression of TEAD1 expression via targeting by miR-133a1. This identification of a TH-regulated microRNA therefore sheds new light on how TH achieves its diverse biological activities.


2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Luting Wu ◽  
Li Ran ◽  
Hedong Lang ◽  
Min Zhou ◽  
Li Yu ◽  
...  

An amendment to this paper has been published and can be accessed via the original article.


2020 ◽  
Vol 77 ◽  
pp. 108297 ◽  
Author(s):  
Wanxue Wen ◽  
Xiaoling Chen ◽  
Zhiqing Huang ◽  
Daiwen Chen ◽  
Hong Chen ◽  
...  

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