Quantitation of Ofloxacin, Tinidazole, Terbinafine Hydrochloride, and Clobetasol propionate in topical cream formulation by chromatographic methods

2021 ◽  
pp. 1-13
Author(s):  
Kunjan B. Bodiwala ◽  
Pinal M. Rana ◽  
Nidhi T. Patel ◽  
Dipen K. Sureja ◽  
Anuradha K. Gajjar
Keyword(s):  
Clobetasol Propionate ◽  
Terbinafine Hydrochloride ◽  
Topical Cream ◽  
Chromatographic Methods ◽  
Cream Formulation

A Tutorial for Developing a Topical Cream Formulation Based on the Quality by Design Approach

2018 ◽  
Vol 107 (10) ◽  
pp. 2653-2662 ◽  
Author(s):  
Ana Simões ◽  
Francisco Veiga ◽  
Carla Vitorino ◽  
Ana Figueiras
Keyword(s):  
Quality By Design ◽  
Design Approach ◽  
Topical Cream ◽  
Cream Formulation ◽  
Quality By Design Approach

scholarly journals Role of clobetasol propionate 0.025% topical therapy in various dermatoses

2021 ◽  
Author(s):  
Vishalakshi Vishwanath ◽  
Arvind Chaudhary ◽  
Ankit Agarwal ◽  
Bhukya Jyothi ◽  
C. Chitharanjan ◽  
...  
Keyword(s):  
Topical Therapy ◽  
Case Series ◽  
Serum Levels ◽  
Hand Eczema ◽  
Clobetasol Propionate ◽  
Cream Formulation ◽  
Chronic Hand Eczema ◽  
Therapeutic Benefits ◽  
Skin Conditions

The anti-inflammatory and vasoconstrictive properties of topical corticosteroids (TCs) contribute in providing therapeutic benefits in several skin conditions, including atopic eczema, localized vitiligo, psoriasis, and chronic hand eczema. Clobetasol propionate (CP) is the most common topical agent used for psoriasis management and demonstrates an efficacy superior to other TCs. A new CP 0.025% cream formulation has demonstrated hypoallergenic effects due to the absence of known contact allergens, such as propylene glycol, short-chain alcohols, and sorbitol-based emulsifiers. Lower CP serum levels and less hypothalamic–pituitary–adrenal axis suppression with CP 0.025% cream formulation than with CP 0.05% ensure better safety. The present case series discusses the clinical experience of using CP 0.025% cream in various dermatological conditions.

scholarly journals Development and validation of different spectrophotometric and chromatographic methods for determination of clotrimazole and hydrocortisone in a topical cream

2017 ◽  
Vol 8 (4) ◽  
pp. 371-377 ◽  
Author(s):  
Michel Yousry Fares ◽  
Maha Mohamed Abdelrahman ◽  
Hamdy Mohamed Abdel-Rahman ◽  
Nada Sayed Abdelwahab
Keyword(s):  
Topical Cream ◽  
Chromatographic Methods ◽  
Development And Validation

scholarly journals Voriconazole topical cream formulation: evidence for stability and antifungal activity

2020 ◽  
Vol 56 (3) ◽  
pp. 106083
Author(s):  
Camille Bouchand ◽  
David Nguyen ◽  
Philippe-Henri Secretan ◽  
Fabrice Vidal ◽  
Romain Guery ◽  
...  
Keyword(s):  
Antifungal Activity ◽  
Topical Cream ◽  
Cream Formulation

scholarly journals Management of diabetic foot ulcers: a 25% lidocaine topical cream formulation design, physicochemical and microbiological assessments

2018 ◽  
Vol 27 (3) ◽  
pp. 162-167
Author(s):  
Hassane Sadou Yayé ◽  
Antoine Faucheron ◽  
Léa Dupont ◽  
Fadwa El Kouari ◽  
Arnaud Fekkar ◽  
...  
Keyword(s):  
Diabetic Foot ◽  
Foot Ulcers ◽  
Diabetic Foot Ulcers ◽  
Formulation Design ◽  
Topical Cream ◽  
Cream Formulation

Development of an HPLC method for the analysis of Apomine in a topical cream formulation

2006 ◽  
Vol 40 (4) ◽  
pp. 975-980 ◽  
Author(s):  
Philip J. Kuehl ◽  
B. Steven Angersbach ◽  
Steven P. Stratton ◽  
Paul B. Myrdal
Keyword(s):  
Hplc Method ◽  
Topical Cream ◽  
Cream Formulation

In vitro–in vivocorrelation study for the dermatopharmacokinetics of terbinafine hydrochloride topical cream

2012 ◽  
Vol 39 (9) ◽  
pp. 1372-1377 ◽  
Author(s):  
Suwadee Saeheng ◽  
Wichit Nosoongnoen ◽  
Supenya Varothai ◽  
Korbtham Sathirakul
Keyword(s):  
Terbinafine Hydrochloride ◽  
Topical Cream

scholarly journals Optimization And Evaluation Of Polyherbal Topical Cream

2021 ◽  
Vol 12 (1) ◽  
pp. 940-946
Author(s):  
Sameer Shafi ◽  
Shendarkar G R
Keyword(s):  
Plant Extracts ◽  
Skin Diseases ◽  
Ocimum Sanctum ◽  
Antimicrobial Spectrum ◽  
Topical Cream ◽  
Cream Formulation ◽  
Herbal Plants ◽  
Improve Patient ◽  
Evaluation Parameters ◽  
Potential Antimicrobial Activity

Herbal plants and their combination report therapeutic as a well synergistic effect that has been recognized in medicine. So, taking into account this factor, the polyherbal topical cream formulation was prepared by using plant extracts to improve patient compliance, enhance antimicrobial spectrum and enhance aesthetic properties. The study focused on the topical polyherbal cream formulation for delivery of the active constituents present in plants to improve skin diseases. The plant extracts of Ocimum sanctum (OS), Rubia cordifolia (RC), Glycyrrhiza glabra (GG) were utilized for the preparation of cream. The formulated cream was subjected to different evaluation parameters and the results depicted that the spreadability of the formulation was low (17.80 ± 1.10g. cm/sec) and that indicates trouble-free spreading, free from grittiness. In rheological properties all the cream formulations also exhibited the same non-Newtonian behaviour. Polyherbal topical cream showed potential antimicrobial activity against all selected microorganisms. Polyherbal topical cream (PHC-5) was ideal in terms of viscosity than other formulations and showed good drug release. Thus, the formulated polyherbal cream was found to be stable in terms of all physicochemical properties.

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