In vitro activity of plazomicin against quinolone-resistant gram-negative bacteria isolated from catheter-associated urinary tract infections

2021 ◽  
pp. 1-7
Author(s):  
Marwa Mohamed Ezzat Abd-Elmonsef ◽  
Salah Nagla ◽  
Mohamed Elsayed Afandy ◽  
Sara Youssef Maxwell
2018 ◽  
Vol 5 (7) ◽  
Author(s):  
Jeanne B Forrester ◽  
Lisa L Steed ◽  
Barbara A Santevecchi ◽  
Patrick Flume ◽  
Gloria E Palmer-Long ◽  
...  

Abstract Ceftolozane/tazobactam (C/T) was tested and compared against 93 nonfermenting, Gram-negative clinical isolates from cystic fibrosis specimens. Based on current breakpoints for intra-abdominal and urinary tract infections (which may not be appropriate for pulmonary infections), C/T was found to be the most active agent against P. aeruginosa (95.7% susceptible), followed by piperacillin/tazobactam (89.4% susceptible). For other Gram-negative pathogens included, C/T had varying activity.


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