Lurking below: massive choroidal invasion under a calcified tumor after attempted conservative therapy for retinoblastoma

The objective: to еxplore the relationship between the activity of endometrial proliferation and the state of the local immune response in the uterus in the conditions berprestasi process. Patients and methods. Examined 228 women of reproductive and perimenopausal age with endometrial pathology using ultrasound and then performing hysteroresectoscopy. Determination of the concentrations of the cytokines IL-1, IL-2, IL-6 and TNF was performed by solid phase ELISA. Results. Found a trend that confirms the loss of sensitivity to hormones at the stage of malignancy of the endometrium and can be used as diagnostic determinants in determining the nature of intrauterine pathology and criterion of the effectiveness of conservative therapy. Conclusion. Improving etiopatogenetice approach to the therapy of hyperplastic proce.sses of endometrium with determination of receptor phenotype of the endometrium is a research direction in modern gynecology, which will help to improve the results of treatment and prevention of intrauterine pathology. Key words: endometrial hyperplasia,the receptors for progesterone and estrogen, immunohistochemical method.

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Conservative Therapy through Adequate Doctor Patient Interaction Improves outcomes in Patients Suffering from Mild and Moderate Knee Osteoarthritis

International Journal of Healthcare Education & Medical Informatics ◽

10.24321/2455.9199.201712 ◽

2018 ◽

Vol 04 (04) ◽

pp. 1-2

Author(s):

M Sharma ◽

Keyword(s):

Knee Osteoarthritis ◽

Conservative Therapy ◽

Patient Interaction

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Cesarean scar defects: diagnosis and treatment in non-pregnant women

GYNECOLOGY ◽

10.26442/20795696.2020.3.200189 ◽

2020 ◽

Vol 22 (3) ◽

pp. 6-10

Author(s):

Sergey A. Martynov

Keyword(s):

Magnetic Resonance Imaging ◽

Surgical Treatment ◽

Magnetic Resonance ◽

Genital Tract ◽

Conservative Therapy ◽

Clinical Manifestations ◽

Subsequent Pregnancy ◽

Resonance Imaging ◽

Diagnostic Features ◽

Pregnancy And Childbirth

The aim of the review was to summarize information on clinical manifestations, diagnostic features, as well as methods for correction of scar defects after cesarean section (CS) outside pregnancy. Lack of the scar after CS, niche, isthmocele are a myometrium defect in the area of scar after CS, which is most often detected by ultrasound, sonohysterography or magnetic resonance imaging and is manifested by postmenstrual bleeding from the genital tract. In some cases, it can cause menorrhagia, dyspareunia, pelvic pain, infertility, uterine rupture during subsequent pregnancy and childbirth. Conservative therapy or surgical treatment with laparoscopy, laparotomy or vaginal approach is carried out depending on the symptoms, size of the defect, the thickness of the residual myometrium, as well as the womans reproductive plans.

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Efficacy of conservative therapy in older people with nonspecific low back pain: A systematic review with meta-analysis and GRADE recommendations

Archives of Gerontology and Geriatrics ◽

10.1016/j.archger.2020.104177 ◽

2020 ◽

Vol 90 ◽

pp. 104177 ◽

Cited By ~ 2

Author(s):

Lorena K.B. Amaral ◽

Mateus B. Souza ◽

Mariana G.M. Campos ◽

Vanessa A. Mendonça ◽

Alessandra Bastone ◽

...

Keyword(s):

Systematic Review ◽

Low Back Pain ◽

Back Pain ◽

Older People ◽

Conservative Therapy ◽

Meta Analysis ◽

Low Back

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Conservative Therapy for Peyronie’s Disease: a Contemporary Review of the Literature

Current Urology Reports ◽

10.1007/s11934-020-01024-8 ◽

2021 ◽

Vol 22 (2) ◽

Author(s):

Ayad Yousif ◽

Caleb Natale ◽

Wayne J. G. Hellstrom

Keyword(s):

Conservative Therapy ◽

Peyronie’S Disease ◽

Review Of The Literature ◽

Peyronie's Disease

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Successful Treatment of Massive Choroidal Invasion in Retinoblastoma with Intraarterial Chemotherapy (Ophthalmic Artery Chemosurgery)

Ophthalmology Retina ◽

10.1016/j.oret.2020.12.018 ◽

2020 ◽

Author(s):

David H. Abramson ◽

Y. Pierre Gobin ◽

Ira J. Dunkel ◽

Jasmine H. Francis

Keyword(s):

Successful Treatment ◽

Ophthalmic Artery ◽

Intraarterial Chemotherapy ◽

Choroidal Invasion

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Management of Spontaneous Isolated Mesenteric Artery Dissection: A Systematic Review

Scandinavian Journal of Surgery ◽

10.1177/14574969211000546 ◽

2021 ◽

pp. 145749692110005

Author(s):

S. Acosta ◽

F. B. Gonçalves

Keyword(s):

Risk Factors ◽

Systematic Review ◽

Superior Mesenteric Artery ◽

Mesenteric Artery ◽

Conservative Therapy ◽

Case Series ◽

Celiac Artery ◽

Artery Dissection ◽

Covered Stents ◽

Bowel Infarction

Background and Aims: There are increasing reports on case series on spontaneous isolated mesenteric artery dissection, that is, dissections of the superior mesenteric artery and celiac artery, mainly due to improved diagnostic capacity of high-resolution computed tomography angiography performed around the clock. A few case–control studies are now available, while randomized controlled trials are awaited. Material and Methods: The present systematic review based on 97 original studies offers a comprehensive overview on risk factors, management, conservative therapy, morphological modeling of dissection, and prognosis. Results and Conclusions: Male gender, hypertension, and smoking are risk factors for isolated mesenteric artery dissection, while the frequency of diabetes mellitus is reported to be low. Large aortomesenteric angle has also been considered to be a factor for superior mesenteric artery dissection. The overwhelming majority of patients can be conservatively treated without the need of endovascular or open operations. Conservative therapy consists of blood pressure lowering therapy, analgesics, and initial bowel rest, whereas there is no support for antithrombotic agents. Complete remodeling of the dissection after conservative therapy was found in 43% at mid-term follow-up. One absolute indication for surgery and endovascular stenting of the superior mesenteric artery is development of peritonitis due to bowel infarction, which occurs in 2.1% of superior mesenteric artery dissections and none in celiac artery dissections. The most documented end-organ infarction in celiac artery dissections is splenic infarctions, which occurs in 11.2%, and is a condition that should be treated conservatively. The frequency of ruptured pseudoaneurysm in the superior mesenteric artery and celiac artery dissection is very rare, 0.4%, and none of these patients were in shock at presentation. Endovascular therapy with covered stents should be considered in these patients.

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Hiflex Foot Gear improves Quality of life in patients with osteoarthritis of the ankle

Foot & Ankle Orthopaedics ◽

10.1177/2473011418s00529 ◽

2018 ◽

Vol 3 (3) ◽

pp. 2473011418S0052

Author(s):

Akiyama Yui ◽

Takaaki Hirano ◽

Hisateru Niki

Keyword(s):

Quality Of Life ◽

Physical Function ◽

Conservative Therapy ◽

Japanese Society ◽

Daily Life ◽

Social Functions ◽

Ankle Osteoarthritis ◽

Custom Made ◽

Perception Of Health

Category: Ankle Arthritis Introduction/Purpose: There are few reports describing conservative therapy for ankle osteoarthritis. Hiflex Foot Gear (HFG) is a custom-made polyethylene ankle–foot orthosis developed to permit slight mobility of the ankle while providing adequate ankle support. The purpose of this study was to validate the hypothesis that HFG improves the quality of life (QOL) in patients with ankle osteoarthritis.Subjects and methods. Methods: Ten ankles from eight patients (one man, seven women) diagnosed with ankle osteoarthritis at this hospital, prescribed an HFG, and observed for follow-up for at least 3 months were included in this study. The patients’ mean age was 69.9 (range: 46?85) years. Patients were classified as Takakura–Tanaka stage IIIa (2 ankles), stage IIIb (2 ankles), stage IV (6 ankles), with a mean observation period of 8.9 (range: 3?13) months. Clinical evaluations were made before and 3 months after wearing the orthosis. The ankle/hindfoot scale of the Japanese Society for Surgery of the Foot (JSSF) Standard Rating System and the Self-Administered Foot Evaluation Questionnaire (SAFE-Q) subscale of the Japanese Orthopaedic Association/Japanese Society for Surgery of the Foot, respectively, were used for making evaluations. Scores were compared using a paired t-test. Results: JSSF scores improved from 55.1 points at baseline to 71.4 points after wearing the HFG (p < 0.001). According to the SAFE-Q subscales, changes after wearing the HFG were as follows: 28.9 to 61.9 points for items related to pain (p < 0.001), 36.9 to 53.7 points for those related to physical function and daily life (p = 0.001), 31.3 to 58.9 points for those related to social functions (p = 0.002), and from 31.3 to 65.0 points for those related to overall perception of health (p < 0.001); items related to shoes showed no substantial change (from 52.1 to 53.6 points). Conclusion: Our results revealed that wearing the HFG improved pain in patients with severe ankle osteoarthritis. Retained flexibility in the ankle range of motion was believed to be the factor underlying improvements in physical function and daily life, social functions, and overall perception of health. HFG is a potential option for conservative therapy in patients who cannot obtain sufficient pain control during the preoperative waiting period or in those who do not wish to undergo surgery.

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