Chemical composition, anti-inflammatory, molluscicidal and free-radical scavenging activities of the leaves ofFicus radicans‘Variegata’ (Moraceae)

2012 ◽  
Vol 26 (4) ◽  
pp. 323-330 ◽  
Author(s):  
Maria Augusta Naressi ◽  
Marcos Alessandro dos Santos Ribeiro ◽  
Ciomar Aparecida Bersani-Amado ◽  
Maria Lucilia M. Zamuner ◽  
Willian Ferreira da Costa ◽  
...  
2021 ◽  
Vol 69 (2) ◽  
Author(s):  
Muhammed M. Hürkul ◽  
Sezen Yilmaz Sarialtin ◽  
Ayşegül Köroğlu ◽  
Tülay Çoban

Avocado (Persea americana Mill.) is a member of Lauraceae with one-seeded berry fruit and cultivated in all tropical, subtropical regions in the world and in the Southern coast region of Turkey. Oxidative damage caused by UV can trigger inflammation, resulting in serious inflammatory skin diseases including eczema, seborrheic dermatitis, hyperpigmentation and ageing. Enzyme inhibitors involved in melanogenesis, such as tyrosinase, have been used recently for hyperpigmentation and skin diseases in cosmetic products. Objective: This study aimed to evaluate the antioxidant, anti-inflammatory, anti-tyrosinase activities and total polyphenolic contents of the different parts of P. americana fruit. Methods: The fruit was divided into exocarp, mesocarp, seed, and then methanol and n-hexane extracts were prepared. DPPH and ABTS free radical scavenging capacities and inhibitory potentials on lipid peroxidation were determined to investigate the antioxidant potentials of the extracts. Anti-inflammatory activities of the extracts were evaluated by measuring the stabilization level of the human red blood cell membrane. The tyrosinase inhibitory activities of the samples were determined using mushroom tyrosinase. Results: In general methanol extracts possessed remarkable higher DPPH free radical scavenging activities than n-hexane extracts. The highest activity was determined in methanol extracts of seed (4.17 ± 0.04 mg/mL) followed by exocarp (5.25 ± 0.05 mg/mL). Overall methanol extracts possessed higher ABTS free radical scavenging activities than n-hexane extracts. The greatest ABTS free radical scavenging activity was obtained in methanol extracts of seed (0.03 ± 0.01 mg/mL). In the anti-lipid peroxidation assay, the greatest activity was noticed in methanol extracts of seed (7.71 ± 0.36 µg/mL) followed by exocarp (12.12 ± 0.34 µg/mL), while all n-hexane extracts were inactive. Overall methanol extracts exhibited higher anti-inflammatory and antioxidant properties than n-hexane extracts. However, the maximum anti-tyrosinase activity was determined in n-hexane extracts of exocarp (0.40 ± 0.01 mg/mL) followed by seed (0.46 ± 0.01 mg/mL). Conclusions: These extracts are promising candidates for use as natural products-based antioxidant and anti-inflammatory properties in inflammation-related disease, and also anti-tyrosinase properties in dermatological applications.


2014 ◽  
Vol 9 (10) ◽  
pp. 1934578X1400901
Author(s):  
Zihao Zhou ◽  
Jun Tang ◽  
Xueping Song

The chemical composition of the essential oil from roots and rhizomes of Ligularia hodgsonii was analyzed by gas chromatography (GC) and GC-mass spectrometry (MS). Forty-seven components were identified, representing 77.0% of the total oil. The main constituents were l-(+)-ascorbic acid 2,6-dihexadecanoate (15.7%), selina-6-en-4-ol (8.4%) and 9,10-dimethyl-1,2,3,4,5,6,7,8-octahydroanthracene (6.6%). The free radical scavenging activities of the essential oil, aqueous extract, ethanolic extract, and crude polysaccharides of L. hodgsonii, as well as some of their major components, were investigated using DPPH and ABTS assays. The essential oil displayed a lower capacity to quench free radicals than the extracts; the ethanolic and aqueous extracts showed considerably higher antioxidant potential that deserves further study.


Phytomedicine ◽  
2014 ◽  
Vol 21 (11) ◽  
pp. 1298-1302 ◽  
Author(s):  
V.T. de Lima ◽  
M.C. Vieira ◽  
C.A.L. Kassuya ◽  
C.A.L. Cardoso ◽  
J.M. Alves ◽  
...  

2018 ◽  
Vol 28 ◽  
pp. 69-75 ◽  
Author(s):  
Paul Djouonzo Toukam ◽  
Maurice Fotsing Tagatsing ◽  
Lauve Rachel Tchokouaha Yamthe ◽  
Gakul Baishya ◽  
Nabin Chandra Barua ◽  
...  

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