Antioxidant, xanthine oxidase and lipoxygenase inhibitory activities and phenolics ofBauhinia rufescensLam. (Caesalpiniaceae)

2012 ◽  
Vol 26 (11) ◽  
pp. 1069-1074 ◽  
Author(s):  
M. Compaoré ◽  
C.E. Lamien ◽  
A. Lamien-Meda ◽  
L. Vlase ◽  
M. Kiendrebeogo ◽  
...  
2020 ◽  
Vol 24 (14) ◽  
pp. 1610-1642 ◽  
Author(s):  
Ahmed El-Mekabaty ◽  
Hassan A. Etman ◽  
Ahmed Mosbah ◽  
Ahmed A. Fadda

Barbituric, thiobarbituric acids and their related analogs are reactive synthons for the synthesis of drugs and biologically, and pharmaceutically active pyrimidines. The present review aimed to summarize the recent advances in the synthesis of different alkylsubstituted, fused cycles, spiro-, and binary heterocycles incorporated pyrimidine skeleton based on barbituric derivatives. In this sequence, the eco-friendly techniques under catalytic conditions were used for the diverse types of multicomponent reactions under different conditions for the synthesis of various types of heterocycles. Nano-catalysts are efficient for the synthesis of these compounds in high yields and effective catalyst reusability. The compounds are potent antibacterial, cytotoxic, xanthine oxidase inhibitory activities, and attend as urease inhibitors. The projected mechanisms for the synthesis of pyranopyrimidines, benzochromenopyrimidines, chromeno-pyranopyrimidines, spiroxyindoles, oxospiro-tricyclic furopyrimidines, pyrimidine-based monoand bicyclic pyridines were discussed. The potent and diverse biological activities for instance, antioxidant, antibacterial, cytotoxic, and xanthine oxidase inhibitory activities, as well as urease inhibitors, are specified.


2018 ◽  
Vol 18 (8) ◽  
pp. 468-474
Author(s):  
Basim Jasim Hameed ◽  
Falah Hassan Shari ◽  
Usama Hamid Ramadhan

2010 ◽  
Vol 13 (8) ◽  
pp. 362-368 ◽  
Author(s):  
N.T.R. Meda ◽  
A. Lamien-Med ◽  
M. Kiendrebeo ◽  
C.E. Lamien ◽  
A.Y. Coulibaly ◽  
...  

RSC Advances ◽  
2011 ◽  
Vol 1 (1) ◽  
pp. 135 ◽  
Author(s):  
Yan Hua Qin ◽  
Jie Zhang ◽  
Jiang Tao Cui ◽  
Zhi Kai Guo ◽  
Nan Jiang ◽  
...  

Molecules ◽  
2011 ◽  
Vol 16 (5) ◽  
pp. 3580-3596 ◽  
Author(s):  
Xiao-Dong Li ◽  
Shuai-Tao Kang ◽  
Guo-Yu Li ◽  
Xian Li ◽  
Jin-Hui Wang

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