(-)-Grandiflorimine, a new dibenzopyrrocoline alkaloid with cholinesterase inhibitory activity from Illigera grandiflora

2019 ◽  
pp. 1-7
Author(s):  
Xuejiao Li ◽  
Jianwei Dong ◽  
Dong Gan ◽  
Dijiao Zhou ◽  
Xueyun Cai ◽  
...  
Keyword(s):  
Inhibitory Activity ◽  
Cholinesterase Inhibitory Activity

7-Amine-spiro[chromeno[4,3-b]quinoline-6,1′-cycloalkanes]: Synthesis and cholinesterase inhibitory activity of structurally modified tacrines

2021 ◽  
Vol 108 ◽  
pp. 104649 ◽  
Author(s):  
Letícia B. Silva ◽  
Pablo A. Nogara ◽  
Paula T. Halmenschelager ◽  
Jéssica C. Alvim ◽  
Fernanda D'A. Silva ◽  
...  
Keyword(s):  
Inhibitory Activity ◽  
Cholinesterase Inhibitory Activity

scholarly journals Isolation and Cholinesterase Inhibitory Activity of Narcissus Extracts and Amaryllidaceae Alkaloid

2013 ◽  
Vol 8 (6) ◽  
pp. 1934578X1300800 ◽  
Author(s):  
Lucie Cahlíková ◽  
Miroslav Ločárek ◽  
Nina Benešová ◽  
Radim Kučera ◽  
Jakub Chlebek ◽  
...  
Keyword(s):  
Biological Activity ◽  
Inhibitory Activity ◽  
Mass Spectra ◽  
Dependent Manner ◽  
Inhibition Activity ◽  
Narcissus Poeticus ◽  
Cholinesterase Inhibitory Activity ◽  
Alkaloid Extracts ◽  
Dose Dependent ◽  
Retention Indexes

Alkaloid extracts of eleven Narcissus (Amaryllidaceae) species and varieties were studied with respect to their acetylcholinesterase (HuAChE) and butyrylcholinesterase (HuBuChE) inhibitory activity and alkaloid patterns. Forty-two alkaloids were determined by GC/MS, and thirty of them identified from their mass spectra, retention times and retention indexes. Promising HuAChE inhibition activity was demonstrated by nine Narcissus taxa and HuBuChE inhibition by Narcissus poeticus cv. Pink Parasol with an IC50 value of 3.3 ± 0.5 μg/mL. The alkaloid identified as (11C- S)-homolycorine was isolated in pure form from Narcissus Sir W. Churchill using preparative TLC and was tested for its biological activity. Homolycorine inhibited HuAChE and HuBuChE in a dose-dependent manner with IC50 values of 63.7±4.3 μM and 151.0±15.2 μM, respectively.

Synthesis and acetyl cholinesterase inhibitory activity of new oxazole, 1, 2, 4 - triazole derivatives bearing carbamazepine as nucleus

2020 ◽  
Author(s):  
Amjad Gali Eliwi ◽  
Zainab Zuhair Mohammad Ali ◽  
Fouad A. AL-Saady ◽  
Shaemaa Hadi Abdulsada ◽  
Abdul Jabar Khlaf Atia
Keyword(s):  
Inhibitory Activity ◽  
Acetyl Cholinesterase ◽  
Triazole Derivatives ◽  
Cholinesterase Inhibitory Activity

Synthesis, molecular docking and cholinesterase inhibitory activity of hydroxylated 2-phenylbenzofuran derivatives

2019 ◽  
Vol 84 ◽  
pp. 302-308 ◽  
Author(s):  
Antonella Fais ◽  
Amit Kumar ◽  
Rosaria Medda ◽  
Francesca Pintus ◽  
Francesco Delogu ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Inhibitory Activity ◽  
Cholinesterase Inhibitory Activity

The behaviour and cholinesterase inhibitory activity of fenthion and its products by light and chlorination

2008 ◽  
Vol 57 (3) ◽  
pp. 143-151 ◽  
Author(s):  
Maiko Tahara ◽  
Reiji Kubota ◽  
Hiroshi Tokunaga ◽  
Hiroyuki Nakazawa ◽  
Tetsuji Nishimura
Keyword(s):  
Inhibitory Activity ◽  
Cholinesterase Inhibitory Activity

2-Arylbenzofurans from Artocarpus lakoocha and methyl ether analogs with potent cholinesterase inhibitory activity

2018 ◽  
Vol 143 ◽  
pp. 1301-1311 ◽  
Author(s):  
Umalee Namdaung ◽  
Anan Athipornchai ◽  
Thongchai Khammee ◽  
Mayuso Kuno ◽  
Sunit Suksamrarn
Keyword(s):  
Methyl Ether ◽  
Inhibitory Activity ◽  
Cholinesterase Inhibitory Activity

Salvia leriifolia Benth (Lamiaceae) extract demonstrates in vitro antioxidant properties and cholinesterase inhibitory activity

2010 ◽  
Vol 30 (12) ◽  
pp. 823-830 ◽  
Author(s):  
Monica R. Loizzo ◽  
Rosa Tundis ◽  
Filomena Conforti ◽  
Federica Menichini ◽  
Marco Bonesi ◽  
...  
Keyword(s):  
Inhibitory Activity ◽  
Antioxidant Properties ◽  
Cholinesterase Inhibitory Activity

Synthesis and cholinesterase inhibitory activity of new 2-benzofuran carboxamide-benzylpyridinum salts

2018 ◽  
Vol 80 ◽  
pp. 180-188 ◽  
Author(s):  
Fahimeh Abedinifar ◽  
S. Morteza F. Farnia ◽  
Mohammad Mahdavi ◽  
Hamid Nadri ◽  
Alireza Moradi ◽  
...  
Keyword(s):  
Inhibitory Activity ◽  
Cholinesterase Inhibitory Activity

scholarly journals A Facile Ionic Liquid Promoted Synthesis, Cholinesterase Inhibitory Activity and Molecular Modeling Study of Novel Highly Functionalized Spiropyrrolidines

Molecules ◽  
2015 ◽  
Vol 20 (2) ◽  
pp. 2296-2309 ◽  
Author(s):  
Abdulrahman Almansour ◽  
Raju Kumar ◽  
Natarajan Arumugam ◽  
Alireza Basiri ◽  
Yalda Kia ◽  
...  
Keyword(s):  
Ionic Liquid ◽  
Molecular Modeling ◽  
Inhibitory Activity ◽  
Molecular Modeling Study ◽  
Cholinesterase Inhibitory Activity ◽  
Modeling Study
Sign in / Sign up

Export Citation Format

Share Document